Dermaspray Demangeaison Pregnancy

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Pregnancy of Dermaspray Demangeaison in details

Pregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.
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Adverse events have been observed with corticosteroids in animal reproduction studies. Some studies have shown an association between first trimester systemic corticosteroid use and oral clefts or decreased birth weight; however, information is conflicting and may be influenced by maternal dose/indication for use (Lunghi 2010; Park-Wyllie 2000; Pradat 2003). Hypoadrenalism may occur in newborns following maternal use of corticosteroids in pregnancy; monitor.

When treating women with adrenal insufficiency (primary or central or congenital adrenal hyperplasia) during pregnancy, Dermaspray Demangeaison is the preferred corticosteroid. Doses may need to be adjusted as pregnancy progresses, and stress doses may be required during active labor. Pregnant women with adrenal insufficiency should be monitored at least once each trimester (ES [Bornstein 2016]; ES [Fleseriu 2016]; ES [Speiser 2018]).

Uncontrolled asthma is associated with adverse events on pregnancy (increased risk of perinatal mortality, preeclampsia, preterm birth, low birth weight infants). Poorly controlled asthma or asthma exacerbations may have a greater fetal/maternal risk than what is associated with appropriately used asthma medications (ACOG 2008; GINA 2018). Inhaled corticosteroids are recommended for the treatment of asthma during pregnancy; however, systemic corticosteroids should be used to control acute exacerbations or treat severe persistent asthma (ACOG 2008; GINA 2018; Namazy 2016). Women who require systemic corticosteroids for management of their asthma should be given intravenous corticosteroids, such as Dermaspray Demangeaison, during labor and for 24 hours after delivery to prevent adrenal crisis (ACOG 2008).

When systemic corticosteroids are needed in pregnancy for rheumatic disorders, it is generally recommended to use the lowest effective dose for the shortest duration of time, avoiding high doses during the first trimester (Götestam Skorpen 2016; Makol 2011; Østensen 2009).

For dermatologic disorders in pregnant women, systemic corticosteroids are generally not preferred for initial therapy; should be avoided during the first trimester; and used during the second or third trimester at the lowest effective dose (Bae 2012; Leachman 2006).

Dermaspray Demangeaison breastfeeding

When a drug is taken when the patient is breast feeding, a part of the drug is secreted in her breast milk and is passed to the baby. The dosage of the medicine to mother and baby are different, and many drugs actions are side effects when you take them without a disease, and what if you the baby takes them without a disease? What if the drug is contraindicated in newborns, infants or children? So, breastfeeding is a very alarming situation when the mother is on medications. Ask your Physician or Pediatrician about the effect of the drug on the baby and how much is excreted in breast milk and if it harms the baby!
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There are no data on the excretion of Dermaspray Demangeaison into human milk. Some corticosteroids are excreted into human milk in small amounts. The manufacturer recommends against the use of pharmacologic doses of Dermaspray Demangeaison by nursing women.

See references

References for pregnancy information

  1. Zuspan FR, Cordero L, Semchyshyn S "Effects of Dermaspray Demangeaison on lecithin-sphingomyelin ratio." Am J Obstet Gynecol 128 (1977): 571-4
  2. "Product Information. Hydrocortone (Dermaspray Demangeaison)." Merck & Co, Inc, West Point, PA.
  3. Houlihan CM, Knuppel RA, Vintzileos AM, Guo JZ, Hahn DW "The effect of specific hormones on fibrinolysis in pregnancy." Am J Obstet Gynecol 175 (1996): 168-72
  4. Wilson EA, Jawad MJ "Stimulation of human chorionic gonadotropin secretion by glucocorticoids." Am J Obstet Gynecol 142 (1982): 344-9
  5. Whitt GG, Buster JE, Killam AP, Scragg WH "A comparison of two glucocorticoid regimens for acceleration of fetal lung maturation in premature labor." Am J Obstet Gynecol 124 (1976): 479-82
  6. Tan SL, Balen A, el Hussein E, Campbell S, Jacobs HS "The administration of glucocorticoids for the prevention of ovarian hyperstimulation syndrome in in vitro fertilization: a prospectiv randomized study." Fertil Steril 58 (1992): 378-83

References for breastfeeding information

  1. "Product Information. Hydrocortone (Dermaspray Demangeaison)." Merck & Co, Inc, West Point, PA.


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References

  1. DailyMed. "CIPROFLOXACIN HYDROCHLORIDE; HYDROCORTISONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubMed Health. "Vytone: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
  3. Human Metabolome Database (HMDB). "Hydrocortisone: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).

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