Dexchlorpheniramine Uses

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What is Dexchlorpheniramine?

Dexchlorpheniramine (Dexchlorpheniramine) is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body.

Dexchlorpheniramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Dexchlorpheniramine may also be used for purposes other than those listed in this medication guide.

Dexchlorpheniramine indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Perennial and seasonal allergic rhinitis

Vasomotor rhinitis

Allergic conjunctivitis due to inhalant allergens and foods

Mild, uncomplicated allergic skin manifestations of urticaria and angioedema

Amelioration of allergic reactions to blood or plasma

Dermographism

As therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.

How should I use Dexchlorpheniramine?

Use Dexchlorpheniramine controlled-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Dexchlorpheniramine controlled-release tablets.

Uses of Dexchlorpheniramine in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Dexchlorpheniramine is used to relieve symptoms of sinus congestion, running nose, watery eyes, itching of the nose and throat, and sneezing due to upper respiratory infections (eg. colds), allergies due to food and insect bites and hay fever.

Dexchlorpheniramine description

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.

Dexchlorpheniramine dosage

Dexchlorpheniramine Dosage

Applies to the following strengths: 2 mg/5 mL; 4 mg; 6 mg; 2 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Allergic Reaction

Initial dose: 2 mg (1 teaspoonful) orally every 4 to 6 hours, or 4 to 6 mg of the timed-release preparation at bedtime or every 8 to 10 hours

Usual Adult Dose for Allergic Rhinitis

Initial dose: 2 mg (1 teaspoonful) orally every 4 to 6 hours, or 4 to 6 mg of the timed-release preparation at bedtime or every 8 to 10 hours

Usual Pediatric Dose for Allergic Reaction

2 years to 5 years: 0.5 mg (1/4 teaspoonful) every 4 to 6 hours for children 2 to 5 years old (do not use timed release)

6 years to 11 years: 1 mg (1/2 teaspoonful) every 4 to 6 hours, or 4 mg of the timed-release preparation at bedtime

Usual Pediatric Dose for Allergic Rhinitis

2 years to 5 years: 0.5 mg (1/4 teaspoonful) every 4 to 6 hours for children 2 to 5 years old (do not use timed release)

6 years to 11 years: 1 mg (1/2 teaspoonful) every 4 to 6 hours, or 4 mg of the timed-release preparation at bedtime

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Dosage should be individualized according to the needs and the response of the patient.

Precautions

Dexchlorpheniramine is contraindicated in newborns or premature infants and in nursing mothers.

As in adults, antihistamines may diminish mental alertness in children, in the young children particularly, they may produce excitation.

Because antihistamines may have potent anticholinergic properties, Dexchlorpheniramine meets Beers criteria as a medications that is potentially inappropriate for use in older adults.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about Dexchlorpheniramine

Consumer resources

Other brands: Dexchlorpheniramine

Professional resources

Related treatment guides

Dexchlorpheniramine interactions

See also:
What other drugs will affect Dexchlorpheniramine?

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MAOI may prolong & enhance antihistamine effects which can lead to severe hypotension. W/ alcohol, TCAs, barbiturate or other antidepressants may enhance sedative effect of Dexchlorpheniramine.

Dexchlorpheniramine side effects

See also:
What are the possible side effects of Dexchlorpheniramine?

Applies to Dexchlorpheniramine: controlled-release tablets, syrup

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur while taking Dexchlorpheniramine (the active ingredient contained in Dexchlorpheniramine)

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

Dexchlorpheniramine contraindications

See also:
What is the most important information I should know about Dexchlorpheniramine?

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Use in Newborn or Premature Infants:

This drug should not be used in newborn or premature infants.

Use in Nursing Mothers:

Because of the higher risk of antihistamines for infants generally and for newborns and prematures in particular, antihistamine therapy is contraindicated in nursing mothers.

Use in Lower Respiratory Disease:

Antihistamines should NOT be used to treat lower respiratory tract symptoms including asthma.

Antihistamines are also contraindicated in the following conditions:

Hypersensitivity to Dexchlorpheniramine or other antihistamines of similar chemical structure

Monoamine oxidase inhibitor therapy

Active ingredient matches for Dexchlorpheniramine:

Dexchlorpheniramine


Unit description / dosage (Manufacturer)Price, USD
Tablet; Oral; Dexchlorpheniramine Maleate 2 mg
Dexchlorpheniramine / Honten 2 mg x 1000's
Dexchlorpheniramine / B.C. 2 mg x 1000's

List of Dexchlorpheniramine substitutes (brand and generic names):

Dexchloramine tab 2 mg 100 x 10's (CCM Pharmaceuticals)
Dexchlorpheniramine BJ Benjaosoth 2 mg x 1, 000's
118 milliliter in 1 bottle
3785 milliliter in 1 bottle
473 milliliter in 1 bottle
DEXCPM 6 MG TABLET SR 1 strip / 10 tablet srs each (Yash Pharma Laboratories Pvt Ltd)$ 0.55
Dexcpm 6mg Tablet SR (Yash Pharma Laboratories Pvt Ltd)$ 0.05
Dexcpm SR 6 mg Tablet (Yash Pharma Laboratories Limited)$ 0.03
Dexferin 2 mg x 100's
Dexferin 2 mg x 500's
Dexferin 2 mg x 1000's
Dexil 2 mg Tablet (Oyster Labs Limited)$ 0.02
Dexodil SR 6 mg Tablet (Psychotropics India Limited)$ 0.04
DEXSIL tab 6 mg x 10's (Dermis)
Dextramine 2 mg x 100 x 10's (Camden)
Diominic 2 mg Tablet (Unison Pharmaceuticals)$ 0.01
DIOMINIC 2 MG TABLET 1 strip / 10 tablets each (Unison Pharmaceuticals)$ 0.15
DIOMINIC 6 MG TABLET 1 strip / 10 tablets each (Unison Pharmaceuticals)$ 0.15
DIOMINIC 6 MG TABLET SR 1 strip / 10 tablet srs each (Unison Pharmaceuticals)$ 0.34
Diominic 2mg Tablet (Unison Pharmaceuticals)$ 0.02
Diominic 6mg Tablet (Unison Pharmaceuticals)$ 0.02
Diominic 6mg Tablet SR (Unison Pharmaceuticals)$ 0.03
Diominic SR 6 mg Tablet (Unison Pharmaceuticals)$ 0.02
DIOWIN TABLET 1 strip / 10 tablets each (Theo Pharma Pvt Ltd)$ 0.25
Doneral 2 mg x 3 Blister x 20 Tablet
Doneral 2 mg x 5 Blister x 20 Tablet
Dopola 2 mg x 2 Blister x 15 Tablet
Dopola 2 mg x 1 Bottle 500 Tablet
Doz SR 6 mg Tablet (Daksh Pharma)$ 0.05
DPM 2 mg Tablet (Bio Sciences Pharmakon)$ 0.03
DPM 10 mg Tablet (Bio Sciences Pharmakon)$ 0.04
DPM TABLET 1 strip / 10 tablets each (Bio Sciences Pharmakon)$ 0.56

References

  1. DailyMed. "DEXCHLORPHENIRAMINE MALEATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "Dexchlorpheniramine maleate". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "DEXCHLORPHENIRAMINE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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