What happens if I overdose Dexclorfeniramina?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; and vomiting.
Proper storage of Dexclorfeniramina controlled-release tablets:
Store Dexclorfeniramina controlled-release tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dexclorfeniramina controlled-release tablets out of the reach of children and away from pets.
Overdose of Dexclorfeniramina in details
Antihistamine overdosage reactions may vary from central nervous system depression to stimulation. Stimulation is particularly likely in children. Atropine-like signs and symptoms—dry mouth, fixed, dilated pupils, flushing, and gastrointestinal symptoms may also occur.
If vomiting has not occurred spontaneously the patient should be induced to vomit. This is best done by having the patient drink a glass of water or milk after which the patient should be made to gag. Precautions against aspiration must be taken, especially in infants and children.
Saline cathartics, such as milk of magnesia, draw water into the bowel by osmosis and therefore, are valuable for their action in rapid dilution of bowel content.
Stimulants should not be used.
Vasopressors may be used to treat hypotension.
What should I avoid while taking Dexclorfeniramina?
Use caution when driving, operating machinery, or performing other hazardous activities. Dexclorfeniramina may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Dexclorfeniramina.
Dexclorfeniramina warnings
Antihistamines should be used with considerable caution in patients with:
- Narrow angle glaucoma
- Stenosing peptic ulcer
- Pyloroduodenal obstruction
- Symptomatic prostatic hypertrophy
- Bladder neck obstruction
Use in Children
In infants and children, especially, antihistamines in overdosage may cause hallucinations, convulsions, or death.
As in adults, antihistamines may diminish mental alertness in children. In the young child, particularly, they may produce excitation.
Use in Pregnancy:
Experience with this drug in pregnant women is inadequate to determine whether there exists a potential for harm to the developing fetus.
Use with CNS Depressants:
Dexclorfeniramina Maleate, USP has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, etc.).
Use in Activities Requiring Mental Alertness:
Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating appliances, machinery, etc.
Use in the Elderly (approximately 60 years or older):
Antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients.
What should I discuss with my healthcare provider before taking Dexclorfeniramina?
For all patients taking Dexclorfeniramina (Dexclorfeniramina):
- If you have an allergy to Dexclorfeniramina or any other part of Dexclorfeniramina (Dexclorfeniramina).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have asthma.
- If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days. Taking Dexclorfeniramina (Dexclorfeniramina) within 14 days of those drugs can cause very bad high blood pressure.
- If you are breast-feeding. Do not breast-feed while you take Dexclorfeniramina (Dexclorfeniramina).
Children:
- If your child is a premature baby or is a newborn. Do not give Dexclorfeniramina (Dexclorfeniramina) to a premature baby or a newborn.
This is not a list of all drugs or health problems that interact with Dexclorfeniramina (Dexclorfeniramina).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Dexclorfeniramina (Dexclorfeniramina) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
Dexclorfeniramina precautions
Dexclorfeniramina Maleate, USP has an atropine-like action and, therefore, should be used with caution in patients with:
- History of bronchial asthma
- Increased intraocular pressure
- Hyperthyroidism
- Cardiovascular disease
- Hypertension
Drug Interaction:
MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines.
What happens if I miss a dose of Dexclorfeniramina?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
References
- DrugBank. "Dexchlorpheniramine". http://www.drugbank.ca/drugs/DB13679 (accessed September 17, 2018).
- MeSH. "Histamine H1 Antagonists". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
