Dextromethorphan HBr Uses

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What is Dextromethorphan HBr?

Dextromethorphan HBr is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Dextromethorphan HBr is used to treat a cough.

Dextromethorphan HBr will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan HBr may also be used for purposes not listed in this medication guide.

Dextromethorphan HBr indications

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used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (e.g., sinusitis, bronchitis). Dextromethorphan HBr is a cough suppressant that affects a certain part of the brain (cough center), reducing the urge to cough. Decongestants help relieve stuffy nose symptoms. Antihistamines relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.

How should I use Dextromethorphan HBr?

Use Dextromethorphan HBr as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Dextromethorphan HBr.

Uses of Dextromethorphan HBr in details

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This medication is used for temporary relief of coughs without phlegm that are caused by certain infections of the air passages (e.g., sinusitis, common cold). This product should not usually be used for an ongoing cough from smoking or long-term breathing problems (e.g., chronic bronchitis, emphysema) unless directed by your doctor. This product contains Dextromethorphan HBr. It is a cough suppressant that works by decreasing the feeling of needing to cough.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How to use Dextromethorphan HBr

Take this medication by mouth, usually every 4 to 12 hours as needed or as directed by your doctor. If stomach upset occurs, take with food or milk. Use a medication-measuring device to measure your dose of liquid medication. Do not use a household spoon because you may not get the correct dose. If you are taking a suspension, shake the product well before measuring out your dose.

Dosage is based on the product you are taking and your age, medical condition, and response to treatment. If you are using this medication for self-treatment (without a prescription from your doctor), follow the specific dosing instructions on the packaging to find the correct dose for your age.

If your doctor directs you to take this medication daily, take it regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Improper use of this medication (abuse) may result in serious harm (e.g., brain damage, seizure, death). Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed.

Tell your doctor if your symptoms persist or worsen after more than 1 week or if you also have fever, chills, headache, or rash. These may be signs of a more serious condition.

Dextromethorphan HBr description

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The d-isomer of the codeine analog of levorphanol. Dextromethorphan HBr shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (receptors, N-methyl-D-aspartate) and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.

Dextromethorphan HBr dosage

For adults and children over 12 years Dextromethorphan HBr prescribed on 15 mg 4 times / day, children aged 6 years - 7.5 mg 4 times / day.

Dextromethorphan HBr interactions

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What other drugs will affect Dextromethorphan HBr?

MAO inhibitors (including furazolidone, procarbazine, selegiline) when administered simultaneous with Dextromethorphan HBr may cause adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, lethargy, nausea, cramps, tremor. In combination with tricyclic antidepressants (amitriptyline, etc.) Dextromethorphan HBr may appeal serotonin syndrome and possible subsequent death. Amiodarone, fluoxetine, quinidine, inhibiting system cytochrome P450, may increase the drug concentration in the blood. Tobacco smoke can lead to increased secretion of glands in the background of inhibition of cough reflex. Some inhibitors of CYP450 (such as quinidine) increase and extended effects of this medicine.

Dextromethorphan HBr side effects

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What are the possible side effects of Dextromethorphan HBr?

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Slight drowsiness/dizziness, nausea, or vomiting may occur. Rarely, some people may experience severe drowsiness/dizziness with normal doses. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Dextromethorphan HBr contraindications

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What is the most important information I should know about Dextromethorphan HBr?

Respiratory depression, obstructive airway disease, asthma. Acute alcoholism, convulsive disorders, head injuries, comatose patients, raised intracranial pressure. Pregnancy (prolonged use or high doses at term).

Active ingredient matches for Dextromethorphan HBr:

Dextromethorphan HBr


List of Dextromethorphan HBr substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Dextrometorphan 30 mg
Dextrophan 10 10 mg x 30 Tablet
Dexycron 15 mg x 10 Blister x 10 Tablet
Dexycron 30 mg x 10 Blister x 10 Tablet
Drill ho khan 450 mg x 150 mL
Drill ho khan 150 mg x 150 mL
Drill ho khan 150 mg x 1 Bottle 150 mL vôùi 1 muoãng löôøng 5 mL
Drill ho khan 450 mg x 1 Bottle 150 mL vôùi 1 muoãng löôøng 5 mL
Ersylan 60 mL$ 0.85
Ersylan 120 mL$ 1.06
Extendryl-DM / Strawberry flavor 10 mg/5 mL x 60 mL$ 1.27
Flemonex-DXM 10 mg/5 mL x 60 mL$ 1.24
Fuyuan Dextromethorphan 30 mg x 1 Bottle 100 Tablet
Halmezin 100 mL x 1's (Coronet)$ 1.86
Ko Ko Sou 1 gal
Mersidryl 75 mL (Mersifarma TM)$ 0.87
Methorfar 10 mg x 10 Blister x 10 Tablet
Methorfar 10 mg x 1 Bottle x 180 Tablet
Mytusan DM 10 mg/5 mL x 60 mL (Am-europharma)$ 1.22
PediaTussin 1 Bottle 118 mL
pms-Dexipharm 5 mg x 1 Bottle 200 Tablet
pms-Dexipharm 15 mg x 20 Blister x 10 Tablet
pms-Dexipharm 15 mg x 1 Bottle 200 Tablet
Robitussin Honey 2 mg/1 mL x 1's
Robitussin Honey 1's
Topsil cough 5 mg x 2 Blister x 12 Tablet
Tuseran Pedia DMP 60 mL x 1's$ 1.55
YSP Nospan 30 mg x 10 Blister x 10 Tablet

References

  1. DailyMed. "DEXTROMETHORPHAN HYDROBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "dextromethorphan". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "dextromethorphan". http://www.drugbank.ca/drugs/DB00514 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Dextromethorphan HBr are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dextromethorphan HBr. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Dextromethorphan HBr drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful1
100.0%


Consumer reported price estimates

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1 consumer reported age

Users%
1-51
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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