Diclac ID Dosage
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Dosage of Diclac ID in details
The dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
As a general recommendation, the dose should be individually adjusted. Adverse effects may be minimized by using the lowest effective dose for the shortest duration necessary to control symptoms.
Gastro-Resistant Tablet: The recommended initial daily dose is 100 to 150 mg. In milder cases, as well as for long-term therapy, 75 to 100 mg daily is usually sufficient.
The total daily dose should generally be divided into 2 to 3 doses. To suppress nocturnal pain and morning stiffness, treatment with tablets during the day can be supplemented by the administration of a suppository at bedtime (up to a total maximum daily dose of 150 mg).
In primary dysmenorrhea, the daily dose should be individually adjusted and is generally 50 to 150 mg. A dose of 50 to 100 mg should be given initially and, if necessary, increased over the course of several menstrual cycles up to a maximum of 200 mg/day. Treatment should be started on appearance of the first symptoms and, depending on the symptomatology, continued for a few days.
SR Tablet: The recommended initial daily dose is 100 mg.
In milder cases, as well as for long-term therapy, 100 mg daily is usually sufficient.
Where the symptoms are most pronounced during the night or in the morning, the tablet should preferably be taken in the evening.
Children: Gastro-Resistant Tablet: Children aged 1 year or over and adolescents should be given 0.5 to 2 mg/kg body weight daily in 2 to 3 separate doses, depending on the severity of the disorder. For treatment of juvenile rheumatoid arthritis, the daily dose can be raised up to a maximum of 3 mg/kg daily, given in separate doses.
The maximum daily dose of 150 mg should not be exceeded.
Because of their dosage strength, Diclac ID 50 mg gastro-resistant tablets are not recommended for use in children and adolescents below 14 years of age; Diclac ID 25 mg gastro-resistant tablets could be used in these patients.
SR Tablet: Not suitable for children and adolescents because of the dosage strength.
Elderly (Patients aged 65 or above): No adjustment of the starting dose is required for elderly patients.
Established Cardiovascular Disease or Significant Cardiovascular Risk Factors: Treatment with Diclac ID is generally not recommended in patients with established cardiovascular disease or uncontrolled hypertension. If needed, patients with established cardiovascular disease, uncontrolled hypertension, or significant risk factors for cardiovascular disease should be treated with Diclac ID only after careful consideration and only at doses ≤100 mg daily if treated for more than 4 weeks.
Renal Impairment: Diclac ID is contraindicated in patients with renal failure. No specific studies have been carried out in patients with renal impairment, therefore, no specific dose adjustment recommendations can be made. Caution is advised when administering Diclac ID to patients with mild to moderate renal impairment.
Hepatic Impairment: Diclac ID is contraindicated in patients with hepatic failure.
No specific studies have been carried out in patients with hepatic impairment, therefore, no specific dose adjustment recommendations can be made. Caution is advised when administering Diclac ID to patients with mild to moderate hepatic impairment.
Administration: SR Tablet: Tablets should be swallowed whole with liquid, preferably before meals and must not be divided or chewed.
Injection: Diclac ID injection should not be given for >2 days; if necessary, treatment can be continued with Diclac ID tablets or suppositories.
Injection: IM: The following directions for IM injection must be followed in order to avoid damage to a nerve or other tissue at the injection site.
Dosage is generally 1 75 mg ampoule daily, injected deep intragluteally into the upper outer quadrant. In severe cases (eg, colic), the daily dose can exceptionally be increased to 2 injections, separated by an interval of a few hours (1 into each buttock). Alternatively, it is possible to combine 1 ampoule with other dosage forms of Diclac ID (eg, tablets) up to a maximum daily dosage of 150 mg.
In migraine attacks, clinical experience is limited to initial use of 1 ampoule of 75 mg administered as soon as possible, followed by suppositories up to 100 mg on the same day if required. The total dose should not exceed 175 mg on the 1st day.
IV Infusion: Diclac ID must not be given as an IV bolus injection.
Immediately before starting an IV infusion, Diclac ID must be diluted with saline 0.9% or glucose 5% infusion solution buffered with sodium bicarbonate according to the instructions given in Instructions for Use and Handling under Cautions for Usage.
Two (2) alternative dosage regimens of Diclac ID are recommended.
For the treatment of moderate to severe postoperative pain, 75 mg should be infused continuously over a period of 30 min to 2 hrs. If necessary, treatment may be repeated after a few hours, but the dosage should not exceed 150 mg within any period of 24 hrs.
For the prevention of postoperative pain, a loading dose of 25-50 mg should be infused after surgery over 15 min to 1 hr, followed by a continuous infusion of about 5 mg/hr up to a maximum daily dose of 150 mg.
What other drugs will affect Diclac ID?
Ask your doctor before using Diclac ID if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may cause you to bruise or bleed easily.
Tell your doctor about all your current medicines and any you start or stop using, especially:
This list is not complete. Other drugs may interact with Diclac ID, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Diclac ID interactions
Interactions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Diclac ID, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
Table 2: Clinically Significant Drug Interactions with Diclac ID
ReviewsThe results of a survey conducted on ndrugs.com for Diclac ID are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Diclac ID. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
Consumer reported frequency of useNo survey data has been collected yet
Consumer reported dosesNo survey data has been collected yet
Information checked by Dr. Sachin Kumar, MD Pharmacology