Diclowin PLUS Uses

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Diclowin PLUS indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or Paracetamol (Diclowin PLUS) is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of Paracetamol (Diclowin PLUS). A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Articular syndrome (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout), degenerative and chronic inflammatory diseases of musculoskeletal system (osteochondrosis, osteoarthritis, periartropatii), post-traumatic inflammation of soft tissue and musculoskeletal system (sprains, bruises). Pain in the spine, neuralgia, myalgia, arthralgia, pain and inflammation after surgery or injury, pain in gout, migraine, algomenorrhea, pain with Bursitis, proctitis, colic (biliary and renal), pain in infectious and inflammatory diseases of ENT organs.

For local use: the inhibition of miosis during surgery for cataract prevention of cystoid macular edema associated with removal and lens implantation, inflammatory eye non-infectious nature, post-traumatic inflammation in penetrating and nonpenetrating wound of the eyeball.

Diclowin PLUS description

A biguanide hypoglycemic agent with actions and uses similar to those of metformin. Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)

Diclowin PLUS dosage

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For oral use for adult single dose is 25-50 mg 2-3 times / 24 h. Frequency of admission depends on the dosage form employed, the severity of the disease and is 1-3 times / 24 h, rectally - 1 times / 24 h, for the treatment of acute conditions or the exacerbation of chronic edema use intramuscular in dose of 75 mg.

For children older than 6 years and adolescents daily dose is 2 mg / kg.

Topical applied at a dose of 2-4 g (depending on the size of painful area) on the affected area 3-4 times / 24 h.

When used in ophthalmology frequency and duration of administration are determined individually.

The maximum oral daily dose for adults is 150 mg.

Diclowin PLUS interactions

The use of NSAIDs in patients who are receiving ACE inhibitors may potentiate renal disease states.

In vitro studies have shown that naproxen anion, because of its affinity for protein, may displace from their binding sites other drugs which are also albumin-bound.

Theoretically, the naproxen anion itself could likewise be displaced. Short-term controlled studies failed to show that taking the drug significantly affects prothrombin times when administered to individuals on coumarin-type anticoagulants. Caution is advised nonetheless, since interactions have been seen with other nonsteroidal agents of this class. Similarly, patients receiving the drug and a hydantoin, sulfonamide or sulfonylurea should be observed for signs of toxicity to these drugs.

Concomitant administration of naproxen and aspirin is not recommended because naproxen is displaced from its binding sites during the concomitant administration of aspirin, resulting in lower plasma concentrations and peak plasma levels.

The natriuretic effect of furosemide has been reported to be inhibited by some drugs of this class. Inhibition of renal lithium clearance leading to increases in plasma lithium concentrations has also been reported. Diclowin PLUS and other NSAIDs can reduce the antihypertensive effect of propranolol and other beta-blockers.

Probenecid given concurrently increases naproxen anion plasma levels and extends its plasma half-life significantly.

Caution should be used if naproxen is administered concomitantly with methotrexate. Diclowin PLUS, naproxen sodium and other NSAIDs have been reported to reduce the tubular secretion of methotrexate in an animal model, possibly increasing the toxicity of methotrexate.

Drug/Laboratory Test Interactions

Diclowin PLUS may decrease platelet aggregation and prolong bleeding time. This effect should be kept in mind when bleeding times are determined. The administration of naproxen may result in increased urinary values for 17-ketogenic steroids because of an interaction between the drug and/or its metabolites with m-dinitrobenzene used in this assay. Although 17-hydroxy-corticosteroid measurements (Porter-Silber test) do not appear to be artifactually altered, it is suggested that therapy with naproxen be temporarily discontinued 72 hours before adrenal function tests are performed if the Porter-Silber test is to be used.

Diclowin PLUS may interfere with some urinary assays of 5-hydroxy indoleacetic acid (5HIAA).

Diclowin PLUS side effects

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GI disturbances; headache, dizziness, rash; GI bleeding, peptic ulceration; abnormalities of kidney function. Pain and tissue damage at Inj site (IM); local irritation (rectal); transient burning and stinging (ophthalmic).

Potentially Fatal: Stevens-Johnson syndrome, exfoliative dermatitis, toxic epidermal necrolysis.

Diclowin PLUS contraindications

Diclowin PLUS should not be administered to patients who have previously exhibited hypersensitivity to it.

Active ingredient matches for Diclowin PLUS:

Diclofenac/Paracetamol

Caffeine/Diclofenac/Paracetamol

Diclofenac sodium/paracetamol in India.


Unit description / dosage (Manufacturer)Price, USD
200's$ 4.44
500's$ 11.11
Diclowin Plus Paracetamol 500 mg, Diclofenacsodium 50 mg. TAB / 200$ 4.44
Diclowin Plus Paracetamol 500 mg, Diclofenacsodium 50 mg. TAB / 500$ 11.11
Diclowin Plus 50+500 Tablet$ 0.03
DICLOWIN PLUS 50 MG/325 MG TABLET 1 strip / 10 tablets each (Wings Pharmaceuticals Pvt Ltd)$ 0.28
DICLOWIN PLUS tab 20's (Wings Pharma)$ 0.44
Diclowin Plus Paracetamol 500 mg, Diclofenacsodium 50 mg. TAB / 200$ 4.44
Diclowin Plus Paracetamol 500 mg, Diclofenacsodium 50 mg. TAB / 500$ 11.11
Diclowin Plus PR Tablet (Wings Biotech Ltd)$ 0.03

List of Diclowin PLUS substitutes (brand and generic names):

Diclozed Plus Diclofenac Sodium50mg, Paracetamol 500mg TAB / 10 (Atoz Pharmaceuticals (Zota Healthcare Pvt Ltd))$ 0.19
10's (Atoz Pharmaceuticals (Zota Healthcare Pvt Ltd))$ 0.19
Diclozed Plus Diclofenac sodium 50 mg, Paracetamol 500 mg. TAB / 10 (Atoz Pharmaceuticals (Zota Healthcare Pvt Ltd))$ 0.19
Diclozed Plus 50+500 Tablet (Atoz Pharmaceuticals (Zota Healthcare Pvt Ltd))$ 0.02
Diclozed Plus Diclofenac Sodium50mg, Paracetamol 500mg TAB / 10 (Atoz Pharmaceuticals (Zota Healthcare Pvt Ltd))$ 0.19
DICLOZED PLUS tab 10's (Atoz Pharmaceuticals (Zota Healthcare Pvt Ltd))$ 0.19
Diclozen-P Diclofenac Sodium50mg, Paracetamol 500mg TAB / 10$ 0.32
Diclozen-P Diclofenac Sodium50mg, Paracetamol 500mg TAB / 10$ 0.32
DICNAC P 50MG/325MG TABLET 1 strip / 10 tablets each (Almet Corporation Ltd)$ 0.51
Dicnac P 50 mg/325 mg Tablet (Almet Corporation Ltd)$ 0.05
10's (Almet)$ 0.25
Dicnac-P Diclofenac 50 mg, Paracetamol325 mg. TAB / 10 (Almet)$ 0.25
DICNAC-P tab 10's (Almet)$ 0.25
Dicnac-P Diclofenac 50 mg, Paracetamol325 mg. TAB / 10 (Almet)$ 0.25
3ml (Shince)$ 0.29
Dicnacx-P Diclofenac sodium 25 mg, Paracetamol 75 mg. INJ / 3ml (Shince)$ 0.29
DICNACX-P inj 3ml (Shince)$ 0.29
Dicnacx-P Diclofenac sodium 25 mg, paracetamol 75 mg. INJ / 3ml (Shince)$ 0.29
Dicnap Diclofenac Sodium50mg, Paracetamol 500mg TAB / 4x5x10 (Osmed Formulations (P) Ltd.)
200's (Osmed Formulations (P) Ltd.)
Dicnap Diclofenac sodium 50 mg, paracetamol 500 mg. TAB / 200 (Osmed Formulations (P) Ltd.)
Dicnap 50+500 Tablet (Osmed Formulations (P) Ltd.)$ 0.02
Dicnap Diclofenac Sodium50mg, Paracetamol 500mg TAB / 4x5x10 (Osmed Formulations (P) Ltd.)
DICNAP tab 10's (Osmed Formulations (P) Ltd.)
Dico-P Diclofenac Sodium50mg, Paracetamol 500mg TAB / 10 (Finecure)
200's (Finecure)
Dico-P Diclofenac sodium 50 mg, paracetamol 500 mg. TAB / 200 (Finecure)
Dico-P Diclofenac Sodium50mg, Paracetamol 500mg TAB / 10 (Finecure)
DICO-P tab 10's (Finecure)$ 0.19
Dicol -Plus Diclofenac Na 50mg, Paracetamol 500mg TAB / 10$ 0.10
Dicol -S Diclofenac Na 50mg, Serratiopeptidase 10mg TAB / 10$ 0.87
10's (Ind-Swift Limited)$ 0.10
Dicol Plus 50+500 Tablet (Ind-Swift Limited)$ 0.01
DICOL PLUS tab 10's (Ind-Swift Limited)$ 0.10
Dicoliv -MR Diclofenac K 50mg, Paracetamol325mg, Chlorzoxazone 250mg TAB / 10$ 1.11
Dicoliv Plus Paracetamol 500mg, DiclofenacNa 50mg TAB / 10 (Ind-Swift Limited)$ 0.22
10's (Ind-Swift Limited)$ 0.22
Dicoliv Plus 50+500 Tablet (Ind-Swift Limited)$ 0.02
DICOLIV PLUS 50MG/500MG TABLET 1 strip / 10 tablets each (Ind-Swift Limited)$ 0.07
DICOLIV PLUS tab 10's (Ind-Swift Limited)$ 0.22
Dicoliv Plus 50 mg/500 mg Tablet (Ind-Swift Limited)$ 0.01

References

  1. DailyMed. "DICLOFENAC EPOLAMINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "diclofenac". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Diclowin PLUS are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Diclowin PLUS. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Diclowin PLUS drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive1
100.0%


2 consumers reported time for results

To what extent do I have to use Diclowin PLUS before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 week and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Diclowin PLUS. To get the time effectiveness of using Diclowin PLUS drug by other patients, please click here.
Users%
1 week1
50.0%
1 day1
50.0%


8 consumers reported age

Users%
16-294
50.0%
30-452
25.0%
> 602
25.0%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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