Irritable bowel syndrome & allied conditions eg, chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Symptomatic treatment of abdominal pain, cramps, nonspecific diarrhoea & flatulence. GI spasm secondary to organic diseases eg, diverticulitis, gastritis, duodenitis, oesophagitis, cholecystitis, Crohn's disease, ulcerative colitis, peptic ulcer, gallbladder disease, hiatus hernia, GIT inflammation.
Uses of Doloverina in details
Doloverina is used to treat irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits). It is also used to treat other conditions that involve spasm and pain related to small and large bowel.
Each capsule contains Mebeverine 200 mg.
Doloverina also contains the following excipients: Capsule Content (Granules): Magnesium stearate, polyacrylate dispersion 30%, talc, hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30% and glycerol triacetate. Capsule Shell: Gelatin, titanium dioxide (E171). Printing Ink: Shellac (E904), black iron oxide (E172), propylene glycol, concentrated ammonia solution, potassium hydroxide.
Adults: 1 capsule twice daily (1 in the morning and 1 in the evening).
Special Populations: Elderly, Renal and Hepatic Impairment: No posology studies in elderly, renal and/or hepatically impaired patients have been performed. However, no specific risk for elderly, renal and/or hepatically impaired patients could be identified from available post-marketing data. No dosage adjustment is deemed necessary in these patients.
Missed Dose: In case of ≥1 doses missed, continue with the next dose as prescribed; the missed doses are not to be taken in addition to the regular dose.
Administration: The capsules should be swallowed with a sufficient amount of water (at least 100 mL of water).
It should not be chewed because the coating is intended to ensure a prolonged release mechanism.
No interaction studies have been performed except with alcohol. In vitro and in vivo studies in animals have demonstrated the absence of any interaction between Doloverina and ethanol.
Incompatibilities: Not applicable.
Doloverina side effects
Although adverse effects appear rare, gastrointestinal disturbances, dizziness, headache, insomnia, anorexia and tachycardia have been reported in patients receiving Doloverina.
Hypersensitivity to Doloverina or to any of the excipients of Doloverina.
Active ingredient matches for Doloverina:
Mebeverine in Chile.
Mebeverine hydrochloride in Chile.
|Unit description / dosage (Manufacturer)||Price, USD|
|Tablet, Prolonged Release; Oral; Mebeverine Hydrochloride 200 mg|
List of Doloverina substitutes (brand and generic names):
|Dobecon 100 mg x 1000's|
|Duskonal Retard (Georgia)|
|Duspamen (Bahrain, Oman)|
|Duspatal (Chile, Germany, Italy, Netherlands, Portugal)|
|Capsule; Oral; Mebeverine Hydrochloride 200 mg (Grunenthal)|
|Dragee; Oral; Mebeverine Hydrochloride 135 mg (Grunenthal)|
|Tablet, Film-Coated; Oral; Mebeverine Hydrochloride 100 mg (Grunenthal)|
|Duspatal Retard (Chile, Portugal)|
|Capsule, Retard; Oral; Mebeverine Hydrochloride 200 mg|
|Duspatalin (Argentina, Bahrain, Bangladesh, Belgium, Brazil, Bulgaria, Colombia, Czech Republic, Denmark, Estonia, France, Georgia, Greece, Hong Kong, Hungary, Indonesia, Latvia, Lithuania, Luxembourg, Malaysia, Mexico, Myanmar, Oman, Peru, Philippines, Poland, Romania, Russian Federation, Singapore, Slovakia, Spain, Sri Lanka, Switzerland, Taiwan, Tunisia, Turkey, Venezuela)|
|Capsule, Prolonged Release; Oral; Mebeverine Hydrochloride 200 mg (Abbott Products)|
|Tablet, Film-Coated; Oral; Mebeverine Hydrochloride 100 mg (Abbott Products)|
|Duspatalin 200mg - 30 Capsule (Abbott Products)||$ 26.00|
|Duspatalin 135 mg x 1's (Abbott Products)|
|Duspatalin 135 mg x 5 Blister x 10 Tablet (Abbott Products)|
|Duspatalin 135 mg x 50's (Abbott Products)||$ 10.20|
|Duspatalin 200 mg x 30's (Abbott Products)|
|Duspatalin 100 mg x 50's (Abbott Products)|
|Duspatalin 100 mg x 100's (Abbott Products)||$ 32.49|
|Duspatalin coated tab 135 mg 50's (Abbott Products)|
|Duspatalin 135mg (Bulgaria)|
|Duspatalin 200 mg retard (Hungary)|
|Duspatalin 200mg (Bulgaria)|
|Duspatalin Farma 1000 (Italy)|
|Duspatalin Pediátrico (Mexico)|
|Duspatalin PR (Cyprus)|
|Duspatalin Programmi Sanitari (Italy)|
|Duspatalin Retard (Germany, Oman, Poland, Switzerland)|
|Capsule, Prolonged Release; Oral; Mebeverine Hydrochloride 200 mg (Abbott)|
|Tablet, Film-Coated; Oral; Mebeverine Hydrochloride 100 mg (Abbott)|
|Duspatalin Retard 200 mg x 30's (Abbott)|
|Duspatalin Retard cap 200 mg 30's (Abbott)|
|Duspatalin Retard 200mg (Switzerland)|
- PubChem. "mebeverine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Mebeverine". http://www.drugbank.ca/drugs/DB12554 (accessed September 17, 2018).
- MeSH. "Parasympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
ReviewsThe results of a survey conducted on ndrugs.com for Doloverina are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Doloverina. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
Consumer reported usefulNo survey data has been collected yet
Consumer reported price estimatesNo survey data has been collected yet
Consumer reported time for resultsNo survey data has been collected yet
Consumer reported ageNo survey data has been collected yet
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Information checked by Dr. Sachin Kumar, MD Pharmacology