How times a day do you take this medicine?
What is Dovobet Ointment?
Dovobet Ointment contains a combination of Betamethasone (Dovobet Ointment) and calcipotriene. Betamethasone (Dovobet Ointment) is a steroid. It prevents the release of substances in the body that cause inflammation. Calcipotriene is a form of vitamin D. It works by decreasing the rate of skin cell reproduction.
Dovobet Ointment topical (for the skin) is a combination medicine used to treat plaque psoriasis.
Adults may use the suspension (liquid) form of this medicine on the skin or the scalp. The liquid may be used only on the scalp in children who are at least 12 years old.
Dovobet Ointment topical ointment should be used only on the skin and only by adults.
Dovobet Ointment indications
Dovobet Ointment® (calcipotriene and Betamethasone (Dovobet Ointment) dipropionate) Ointment is indicated for the topical treatment of psoriasis vulgaris in adults 18 years of age and above for up to 4 weeks. The maximum weekly dose should not exceed 100 g. Treatment of more than 30% body surface area is not recommended.
Dovobet Ointment® (calcipotriene and Betamethasone (Dovobet Ointment) dipropionate) Ointment should not be applied to the face, axillae or groin.
How should I use Dovobet Ointment?
Use Dovobet Ointment exactly as it was prescribed for you. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Do not use Dovobet Ointment to treat any condition that has not been checked by your doctor.
Do not take Dovobet Ointment by mouth.
Topical medicine is for use only on the skin. Do not use in the vagina.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Wash your hands before and after applying this medicine, unless you are using the medicine to treat the skin on your hands.
Shake the Dovobet Ointment suspension (liquid) just before using it.
Apply Dovobet Ointment once daily to the affected skin and rub it in gently. Do not spread the medicine over a large skin area. Do not apply to areas of thinner skin (face, underarms, groin) unless your doctor tells you to.
Do not cover the treated skin area. Covering skin treated with a topical steroid can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects.
If you use Dovobet Ointment liquid:
Adults should not use more than 100 grams (1 full bottle) of the liquid in 1 week.
Children age 12 and older should not use more than 60 grams of the liquid in 1 week.
If you use Dovobet Ointment ointment: Do not use more than 100 grams (1 large tube) of the ointment in 1 week. Avoid treating an area that is larger than 30% or one-third of your entire body.
Ask your pharmacist if you have questions about how much to apply each time you use the medicine.
Dovobet Ointment ointment can be applied daily for up to 4 weeks. The liquid can be used daily for up to 8 weeks. Follow your doctor's instructions about your individual treatment schedule.
Call your doctor if your skin condition does not improve after several days of treatment, or if it gets worse while using this medicine.
If you use Dovobet Ointment long-term, you may need frequent medical tests.
Store at room temperature away from moisture and heat. Keep the bottle or tube tightly closed when not in use.
Stop using Dovobet Ointment when your skin clears up, unless your doctor tells you otherwise.
Dovobet Ointment description
Each gram of ointment contains Calcipotriol (Dovobet Ointment) 50 mcg and Betamethasone (Dovobet Ointment) dipropionate 0.5 mg.
Each gram of Dovobet Ointment gel contains Calcipotriol (Dovobet Ointment) monohydrate 50 mcg and Betamethasone (Dovobet Ointment) dipropionate 0.5 mg. It also contains the following excipients: Liquid paraffin, butylhydroxytoluene (E321), polyoxypropylene-15 stearyl ether, all-rac-α-tocopherol, hydrogenated castor oil.
Dovobet Ointment dosage
Instruct patients to shake can prior to using Dovobet Ointment® Foam and to wash their hands after applying the product.
Apply Dovobet Ointment® Foam to affected areas once daily for up to 4 weeks. Rub in Dovobet Ointment® Foam gently. Discontinue use when control is achieved.
Instruct patients not to use more than 60 g every 4 days.
Dovobet Ointment® Foam should not be used with occlusive dressings unless directed by a physician. Dovobet Ointment® Foam is not for oral, ophthalmic, or intravaginal use.
Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site.
Dosage Forms And Strengths
Dovobet Ointment® Foam is a white to off-white opalescent liquid in a pressurized aluminum spray can with a continuous valve and actuator. At administration the product is a white to off-white foam after evaporation of the propellants. Each gram of Dovobet Ointment® Foam contains 52.2 mcg calcipotriene hydrate (equivalent to 50 mcg of calcipotriene) and 0.643 mg of Betamethasone (Dovobet Ointment) dipropionate (equivalent to 0.5 mg of Betamethasone (Dovobet Ointment)).
Storage And Handling
Dovobet Ointment® Foam is a white to off-white opalescent liquid in a pressurized aluminum spray can with a continuous valve and actuator. At administration the product is a white to off-white foam after evaporation of the propellants.
Dovobet Ointment® Foam is available in aluminum cans of:
1 x 60 g (NDC 50222-302-60)
2 x 60 g (NDC 50222-302-66)
- Store Dovobet Ointment® Foam at 20 °- 25°C (68° -77°F); excursions pe rmitted between 15 °-30°C (59°-86°F).
- Contents under pressure. Do not puncture or incinerate. Do not expose to heat or store at temperatures above 120°F (49°C). Do not freeze.
- The product should be used within six m onths after it has been opened.
- Dovobet Ointment® Foam is flammable; avoid heat, flame or smoking when using this product.
Manufactured by: Colep Laupheim GmbH & Co. KG Fockestra
Dovobet Ointment interactions
No interaction studies have been performed.
Incompatibilities: In the absence of compatibility studies, Dovobet Ointment gel must not be mixed with other medicinal products.
Dovobet Ointment side effects
The trial programme for Dovobet Ointment ointment has so far included >2500 patients for Dovobet Ointment ointment and >4,700 patients for Dovobet Ointment Gel and has shown that approximately 10% and 8% of patients can be expected to experience a non-serious undesirable effect for Dovobet Ointment Gel and Ointment, respectively.
Based on data from clinical trials and post-market use, the common undesirable effects are pruritus, rash and burning sensation of skin. Uncommon undesirable effects are skin pain or irritation, dermatitis, erythema, exacerbation of psoriasis, folliculitis and application site pigmentation changes. Pustular psoriasis is a rare undesirable effect.
The individual undesirable effects are listed as follows, starting with the most frequently reported:
Skin and Subcutaneous Tissue Disorders: Common (>1/100 and <1/10): Pruritus, rash, burning sensation of skin. Uncommon (>1/1000 and <1/100): Skin pain or irritation, dermatitis, erythema, exacerbation of psoriasis, folliculitis, application site pigmentation changes. Rare (>1/10,000 and <1/1000): Pustular psoriasis.
Undesirable effects observed for Calcipotriol (Dovobet Ointment) and Betamethasone (Dovobet Ointment), respectively:
Calcipotriol (Dovobet Ointment): Undesirable effects include application site reactions, pruritus, skin irritation, burning and stinging sensations, dry skin, erythema, rash, dermatitis, eczema, aggravated psoriasis, photosensitivity and hypersensitivity reactions including very rare cases of angioedema and facial oedema. Systemic effects after topical use may appear very rarely causing hypercalcaemia or hypercalciuria.
Betamethasone (Dovobet Ointment) (as Dipropionate): Dovobet Ointment contains a potent corticosteroid.
Local reactions can occur after topical use, especially during prolonged application, including skin atrophy, telangiectasia, striae, folliculitis, hypertrichosis, perioral dermatitis, allergic contact dermatitis, depigmentation and colloid milia. When treating psoriasis, there may be a risk of generalised pustular psoriasis.
Systemic effects due to topical use of corticosteroids are rare in adults, however they can be severe. Adrenocortical suppression, cataract, infections and increase of intraocular pressure can occur, especially after long-term treatment. Systemic effects occur more frequently when applied under occlusion (plastic, skin folds), when applied on large areas and during long-term treatment.
Dovobet Ointment contraindications
Hypersensitivity to Calcipotriol (Dovobet Ointment) monohydrate or Betamethasone (Dovobet Ointment) dipropionate gel or to any of the excipients of Dovobet Ointment.
Due to the content of Calcipotriol (Dovobet Ointment), Dovobet Ointment gel is contraindicated in patients with known disorders of calcium metabolism.
Due to the content of corticosteroid, Dovobet Ointment gel is contraindicated in the following conditions: Viral (eg, herpes or varicella) lesions of the skin, fungal or bacterial skin infections, parasitic infections, skin manifestations in relation to tuberculosis or syphilis, perioral dermatitis, atrophic skin, striae atrophicae, fragility of skin veins, ichthyosis, acne vulgaris, acne rosacea, rosacea, ulcers and wounds.
Dovobet Ointment gel is contraindicated in guttate, erythrodermic, exfoliative and pustular psoriasis. It is also contraindicated in patients with severe renal insufficiency or severe hepatic disorders.
Active ingredient matches for Dovobet Ointment:
Betamethasone/calcipotriol in United Kingdom.
List of Dovobet Ointment substitutes (brand and generic names)
|Sort by popularity|
|Unit description / dosage (Manufacturer)||Price, USD|
|Daivobet (Australia, Bahrain, Bangladesh, Bulgaria, China, Colombia, Costa Rica, Czech Republic, Denmark, Dominican Republic, Ecuador, El Salvador, Estonia, Finland, France, Georgia, Germany, Guatemala, Honduras, Hong Kong, Iceland, India, Indonesia, Israel, Latvia, Lithuania, Malaysia, Malta, Norway, Panama, Philippines, Poland, Portugal, Romania, Russian Federation, Singapore, Slovenia, South Korea, Spain, Sweden, Switzerland, Taiwan, Tunisia, Uruguay, Vietnam)|
|Daivobet 15 g x 1's (Win Medicare Pvt Ltd)||$ 23.93|
|Daivobet 30 g (Win Medicare Pvt Ltd)||$ 38.37|
|Daivobet 1 tube 15 g (Win Medicare Pvt Ltd)|
|15g (Win Medicare Pvt Ltd)||$ 12.91|
|Daivobet Skin 15 gm Ointment (Win Medicare Pvt Ltd)||$ 0.82|
|Daivobet oint 15 g x 1's (Win Medicare Pvt Ltd)||$ 22.91|
|Daivobet oint 30 g x 1's (Win Medicare Pvt Ltd)||$ 41.18|
|Daivobet gel 15 g x 1's (Win Medicare Pvt Ltd)|
|Daivobet gel 30 g x 1's (Win Medicare Pvt Ltd)||$ 41.98|
|Daivobet gel 60 g x 1's (Win Medicare Pvt Ltd)|
|DAIVOBET oint 15g (Win Medicare Pvt Ltd)||$ 12.29|
|Daivobet 50 µg/0.5 mg/g (Hungary)|
|Daivobet 50 µg/g + 0,5 mg/g (Austria, Germany)|
|Daivobet 50/500 (Australia, New Zealand)|
|Daivobet D.A.C. (Iceland)|
|Dyvon Plus (Bangladesh)|
|Enstilar (United States)|
|Enstilar 50 μg/g + 0.5 mg/g (Austria)|
|Enstilum (Belgium, Romania)|
|Enstilum 50mcg/0.5mg (Luxembourg)|
|Psorcutan Beta (Germany, Turkey)|
|Taclonex (Argentina, United States)|
|Ointment; Topical; Betamethasone Dipropionate 0.064%; Calcipotriol Hydrate 0.005% (Warner chilcott)|
|100 gram in 1 tube (Warner chilcott)|
|3 gram in 1 tube (Warner chilcott)|
|60 gram in 1 tube (Warner chilcott)|
|Xamiol (Austria, Belgium, Bulgaria, Canada, Denmark, Estonia, Finland, France, Germany, Greece, Iceland, Italy, Latvia, Lithuania, Luxembourg, Malta, Norway, Oman, Philippines, Portugal, Slovenia, Sweden, Switzerland, Taiwan, Tunisia)|
|Gel; Topical; Betamethasone Dipropionate 0.5 mg; Calcipotriol Monohydrate 50 mcg / g (LEO Pharma)|
|Xamiol 30 g (LEO Pharma)||$ 41.98|
|Xamiol 15 g x 1's (LEO Pharma)|
|Xamiol 15 g (LEO Pharma)|
|Xamiol topical gel 30 g x 1's (LEO Pharma)||$ 41.98|
|Xamiol topical gel 15 g x 1's (LEO Pharma)|
|Xamiol 50 Mikrogramm/g + 0,5 mg/g (Germany)|
|Xamiol 50µg/0.5mg/g (Hungary, Luxembourg)|
- DailyMed. "CALCIPOTRIENE HYDRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "BETAMETHASONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "betamethasone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
ReviewsThe results of a survey conducted on ndrugs.com for Dovobet Ointment are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dovobet Ointment. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
Consumer reported usefulNo survey data has been collected yet
Consumer reported price estimatesNo survey data has been collected yet
Consumer reported time for resultsNo survey data has been collected yet
Consumer reported ageNo survey data has been collected yet
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Information checked by Dr. Sachin Kumar, MD Pharmacology