Dravom is an antihistamine that reduces the effects of natural chemical histamine in the body.
Dravom is used to treat or prevent nausea, vomiting, and dizziness associated with motion sickness.
Dravom may also be used for purposes not listed in this medication guide.
Dravom indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Dravom Injection, USP is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
How should I use Dravom?
Use Dravom chewable tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Dravom chewable tablets may be taken with or without food.
Chew thoroughly before swallowing.
Use Dravom chewable tablets exactly as directed on the package, unless instructed differently by your doctor. If you are taking Dravom chewable tablets without a prescription, follow any warnings and precautions on the label.
Take the first dose at least 30 minutes before activity or travel.
If you miss a dose of Dravom chewable tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Dravom chewable tablets.
Uses of Dravom in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Dravom is an antihistamine used to prevent and treat nausea, vomiting and dizziness caused by motion sickness when medication cannot be given by mouth.
Dravom injection should not be used in newborns because of an increased risk of side effects.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
Dravom is also used to treat symptoms of other motion and balance problems such as feelings of dizziness/spinning (vertigo) and inner ear problems (e.g., Meniere's disease). It may also be used to treat nausea and vomiting due to surgery, radiation sickness, side effects of drug treatment, and other causes.
How to use Dravom injection
This medication is injected into a vein (IV), or it can be injected into a muscle by a health care professional, as directed by your doctor. Your dosage is based on your medical condition and response to therapy.
Tell your doctor if your condition persists or worsens.
Dravom description
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An alkaloid from Solanaceae, especially Datura metel L. and Scopola carniolica. Dravom and its quaternary derivatives act as antimuscarinics like atropine, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in urinary incontinence, in motion sickness, as an antispasmodic, and as a mydriatic and cycloplegic.
Dravom dosage
Dravom Dosage
Applies to the following strength(s): 50 mg/mL; 50 mg; 12.5 mg/5 mL; 12.5 mg/4 mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
Motion Sickness
Usual Pediatric Dose for:
Motion Sickness
Additional dosage information:
Renal Dose Adjustments
Liver Dose Adjustments
Precautions
Dialysis
Other Comments
Usual Adult Dose for Motion Sickness
-IM: 50 mg every 4 hours injected intramuscularly as needed; Maximum Dose: 100 mg every 4 hours
-IV: 50 mg every 4 hours injected intravenously over a period of 2 minutes; Maximum Dose: 100 mg every 4 hours
-Oral: 50 to 100 mg orally every 4 to 6 hours; Maximum Dose: 400 mg in 24 hours
Comments:
-For IV administration: Each mL (50 mg) must be diluted in 10 mL of 0.9% sodium chloride injection.
-The first dose should be taken one-half to one hour before starting activity.
-The injectable form is indicated when the oral form is impractical.
Use: Prevention and treatment of nausea, vomiting, dizziness, or vertigo associated with motion sickness.
Usual Pediatric Dose for Motion Sickness
IM: 1.25 mg/kg OR 37.5 mg/m2 injected intramuscularly 4 times a day; Maximum Dose: 300 mg/day
Oral:
-Age 2 to 5: 12.5 to 25 mg orally every 6 to 8 hours; Maximum Dose: 75 mg in 24 hours
-Age 6 to 11: 25 to 50 mg orally every 6 to 8 hours; Maximum Dose: 150 mg in 24 hours
-Age 12 and older: 50 to 100 mg orally every 4 to 6 hours; Maximum Dose: 400 mg in 24 hours
Comments:
-The first dose should be taken one-half to one hour before starting activity.
-The injectable form is indicated when the oral form is impractical.
Use: Prevention and treatment of nausea, vomiting, dizziness, or vertigo associated with motion sickness.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Do not use in patients younger than 2 years unless directed by a doctor.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration Advice:
-The solution form should not be injected intra-arterially.
Storage Requirements:
-This drug should be protected from moisture and stored at 20 to 25 degrees Celsius (68 to 77 Fahrenheit).
General:
-Overdosage: Convulsions, coma, respiratory depression, and drowsiness may occur with overdosage. There is no specific antidote; the manufacturer product information should be consulted for drugs that may be used to treat overdosage effects.
-In mice, the oral LD50 is 203 mg/kg and the intraperitoneal LD50 is 149 mg/kg; the LD50 in rats is 1,320 mg/kg.
-There is no human data indicating this drug is a carcinogen or mutagen.
Patient Advice:
-Avoid alcoholic drinks, sedatives, and tranquilizers while taking this drug.
-This drug may cause side effects such as drowsiness and dizziness that can affect your ability to perform certain activities; avoid driving and potentially hazardous activities such as operating machinery until you know how this drug affects you.
-If overdosage occurs, get immediate medical help or contact a Poison Control Center right away.
More about Dravom
Side Effects
During Pregnancy or Breastfeeding
Dosage Information
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Dravom
Dravom chewable tablets
Dravom tablets
Other brands: Dramamine, Dravom, Driminate, Travel-Eze
The absorption of oral medications may be decreased during the concurrent use of scopolamine because of decreased gastric motility and delayed gastric emptying.
Dravom should be used with care in patients taking other drugs that are capable of causing CNS effects such as sedatives, tranquilizers, or alcohol. Special attention should be paid to potential interactions with drugs having anticholinergic properties; e.g., other belladonna alkaloids, antihistamines (including meclizine), tricyclic antidepressants, and muscle relaxants.
Laboratory Test Interactions
Dravom will interfere with the gastric secretion test.
Applies to Dravom: oral solution, oral tablets, parenteral injection
Side effects include:
Drowsiness, headache, blurred vision, tinnitus, dryness of the mouth and respiratory passages, incoordination, palpitation, dizziness, hypotension.
Paradoxical CNS stimulation in pediatric patients and occasionally in adults.
With IM injection: Pain at the injection site.
Because Dravom (the active ingredient contained in Dravom) contains diphenhydramine, the possibility of other diphenhydramine-related adverse effects should also be considered.
Hypersensitivity to Dravom or any component of the formulation; neonates (injection contains benzyl alcohol)
Canadian labeling: Hypersensitivity to Dravom, its components (diphenhydramine or 8-chlorotheophylline) or any component of the formulation; concurrent use of or use within 14 days following therapy with a monoamine oxidase inhibitor; narrow angle glaucoma; chronic pulmonary disease; prostatic hypertrophy; patients <2 years of age
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