Dumin Side effects

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What are the possible side effects of Dumin?

Get emergency medical help if you have any of these signs of an allergic reaction to Dumin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you suffer a serious side effect from Dumin such as:

Less serious Dumin side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Side effects of Dumin in details

A side effect of any drug can be defined as the unwanted or undesired effect produced by the drug. The side effect can be major or in few medications minor that can be ignored. Side effects not only vary from drug to drug, but it also depends on the dose of the drug, the individual sensitivity of the person, brand or company which manufactures it. If side effects overweigh the actual effect of the medicine, it may be difficult to convince the patient to take the drug. Few patients get specific side effects to specific drugs; in that case, a doctor replaces the drug with another. If you feel any side effect and it troubles you, do not forget to share with your healthcare practitioner.
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Common Reactions: Adverse eactions have been observed in 19% of patients during clinical evaluation; however, only half of these were attributed to Dumin. Treatment was terminated in 5% of all patients due to adverse reactions.

Cardiovascular: Ectopic beats, tachycardia, anginal pain, palpitation, hypotension, vasoconstriction.

Gastrointestinal: Nausea, vomiting.

Nervous system: Headache.

Respiratory: Dyspnea.

Less Common Reactions: Biochemical Abnormalities: Azotemia.

Cardiovascular: Aberrant ventricular conduction, bradycardia, widened QRS complex, hypertension. Gangrene of the feet has occurred in a few patients with preexisting vascular disease. A few cases of peripheral cyanosis have been reported in patients receiving Dumin.

Nervous System: Piloerection, anxiety.

Serious or Life-Threatening Reactions: Gangrene of the feet has occurred following doses of 10-14 mcg/kg/min and higher in a few patients with preexisting vascular disease.

Fatal ventricular arrhythmias have been reported on rare occasions. Extravasation of Dumin may cause necrosis and sloughing of surrounding tissue.

What is the most important information I should know about Dumin?

Dumin contraindications

Contraindication can be described as a special circumstance or a disease or a condition wherein you are not supposed to use the drug or undergo particular treatment as it can harm the patient; at times, it can be dangerous and life threatening as well. When a procedure should not be combined with other procedure or when a medicine cannot be taken with another medicine, it is called Relative contraindication. Contraindications should be taken seriously as they are based on the relative clinical experience of health care providers or from proven research findings.
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If possible before you receive Dumin injection, tell your caregivers if you have pheochromocytoma (tumor of the adrenal gland).

Also tell your caregivers if you have hardened arteries, circulation problems, diabetes, frostbite, Buergers disease, asthma, sulfite allergy, or a history of blood clots.

Tell your doctor about all the prescription and over-the-counter medications you use, especially if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 21 days.

In an emergency situation it may not be possible before you are treated to tell your caregivers about your health conditions or if you are pregnant or breast feeding. Make sure any doctor caring for you afterward knows that you have received this medication.

References

  1. DTP/NCI. "dopamine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
  2. European Chemicals Agency - ECHA. "dopamine: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).
  3. HSDB. "DOPAMINE". https://toxnet.nlm.nih.gov/cgi-bin/s... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Dumin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dumin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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