Duo Plus Tablet Uses

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What is Duo Plus Tablet?

Duo Plus Tablet (acetaminophen) is a pain reliever and a fever reducer. The exact mechanism of Duo Plus Tablet of is not known.

Duo Plus Tablet is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Duo Plus Tablet may also be used for other purposes not listed in this medication guide.

Duo Plus Tablet indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or Duo Plus Tablet is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of Duo Plus Tablet. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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For systemic use of Duo Plus Tablet Sante Naturelle: prevention and treatment of hypo- and avitaminosis of vitamin C; providing increased need for vitamin C during growth, pregnancy, lactation, with heavy loads, fatigue and during recovery after prolonged severe illness; in winter with an increased risk of infectious diseases.

For intravaginal use: chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis) caused by the anaerobic flora (due to changes in pH of the vagina) in order to normalize disturbed vaginal microflora.

How should I use Duo Plus Tablet?

Use Duo Plus Tablet exactly as directed on the label, or as prescribed by your doctor.

Do not use more of this medication than is recommended. An overdose of Duo Plus Tablet can cause serious harm. The maximum amount for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Using more Duo Plus Tablet could cause damage to your liver. If you drink more than three alcoholic beverages per day, talk to your doctor before taking Duo Plus Tablet and never use more than 2 grams (2000 mg) per day. If you are treating a child, use a pediatric form of Duo Plus Tablet. Carefully follow the dosing directions on the medicine label. Do not give the medication to a child younger than 2 years old without the advice of a doctor.

Measure the liquid form of Duo Plus Tablet with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. You may need to shake the liquid before each use. Follow the directions on the medicine label.

The Duo Plus Tablet chewable tablet must be chewed thoroughly before you swallow it.

Make sure your hands are dry when handling the Duo Plus Tablet disintegrating tablet. Place the tablet on your tongue. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

To use the Duo Plus Tablet effervescent granules, dissolve one packet of the granules in at least 4 ounces of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Do not take a Duo Plus Tablet rectal suppository by mouth. It is for use only in your rectum. Wash your hands before and after inserting the suppository.

Try to empty your bowel and bladder just before using the Duo Plus Tablet suppository. Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.

For best results from the suppository, lie down and insert the suppository pointed tip first into the rectum. Hold in the suppository for a few minutes. It will melt quickly once inserted and you should feel little or no discomfort while holding it in. Avoid using the bathroom just after inserting the suppository.

Stop using Duo Plus Tablet and call your doctor if:

Urine glucose tests may produce false results while you are taking Duo Plus Tablet. Talk to your doctor if you are diabetic and you notice changes in your glucose levels during treatment.

Store Duo Plus Tablet at room temperature away from heat and moisture. The rectal suppositories can be stored at room temperature or in the refrigerator.

Uses of Duo Plus Tablet in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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This drug is used to treat mild to moderate pain (from headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and pains) and to reduce fever.

How to use Duo Plus Tablet

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

There are many brands and forms of acetaminophen available. Read the dosing instructions carefully for each product because the amount of acetaminophen may be different between products. Do not take more acetaminophen than recommended.

If you are giving acetaminophen to a child, be sure you use a product that is meant for children. Use your child's weight to find the right dose on the product package. If you don't know your child's weight, you can use their age.

For suspensions, shake the medication well before each dose. Some liquids do not need to be shaken before use. Follow all directions on the product package. Measure the liquid medication with the provided dose-measuring spoon/dropper/syringe to make sure you have the correct dose. Do not use a household spoon.

For rapidly-dissolving tablets, chew or allow to dissolve on the tongue, then swallow with or without water. For chewable tablets, chew thoroughly before swallowing.

Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

For effervescent tablets, dissolve the dose in the recommended amount of water, then drink.

Pain medications work best if they are used as the first signs of pain occur. If you wait until the symptoms have worsened, the medication may not work as well.

Do not take this medication for fever for more than 3 days unless directed by your doctor. For adults, do not take this product for pain for more than 10 days (5 days in children) unless directed by your doctor. If the child has a sore throat (especially with high fever, headache, or nausea/vomiting), consult the doctor promptly.

Tell your doctor if your condition persists or worsens or if you develop new symptoms. If you think you may have a serious medical problem, get medical help right away.

Duo Plus Tablet description

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Duo Plus Tablet is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. Duo Plus Tablet exists as small alkaline deliquescent crystals with a saline tasteacinol was introduced to medicine as a solvent for uric acid. When taken into the body the drug is partly oxidized and partly eliminated unchanged. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successfulacinol was first introduced as an anthelmintic in 1953. A large number of piperazine compounds have anthelmintic Duo Plus Tablet. Their mode of Duo Plus Tablet is generally by paralysing parasites, which allows the host body to easily remove or expel the invading organism.

Duo Plus Tablet dosage

Usual Adult Duo Plus Tablet Dose for Fever:

General Dosing Guidelines: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours orally or rectally.

Duo Plus Tablet 500mg tablets: Two 500 mg tablets orally every 4 to 6 hours

Usual Adult Duo Plus Tablet Dose for Pain:

General Dosing Guidelines: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours orally or rectally.

Duo Plus Tablet 500mg tablets: Two 500 mg tablets orally every 4 to 6 hours

Usual Pediatric Dose for Fever:

Oral or Rectal:

<=1 month: 10 to 15 mg/kg/dose every 6 to 8 hours as needed.

>1 month to 12 years: 10 to 15 mg/kg/dose every 4 to 6 hours as needed (Maximum: 5 doses in 24 hours)

Fever: 4 months to 9 years: Initial Dose: 30 mg/kg (Reported by one study (n=121) to be more effective in reducing fever than a 15 mg/kg maintenance dose with no difference regarding clinical tolerance.)

>=12 years: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours.

Usual Pediatric Dose for Pain:

Oral or Rectal:

<=1 month: 10 to 15 mg/kg/dose every 6 to 8 hours as needed.

>1 month to 12 years: 10 to 15 mg/kg/dose every 4 to 6 hours as needed (Maximum: 5 doses in 24 hours)

Fever: 4 months to 9 years: Initial Dose: 30 mg/kg (Reported by one study (n=121) to be more effective in reducing fever than a 15 mg/kg maintenance dose with no difference regarding clinical tolerance.)

>=12 years: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours.

Duo Plus Tablet interactions

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What other drugs will affect Duo Plus Tablet?

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With the simultaneous use with inducers of microsomal liver enzymes, means having hepatotoxic effect, increasing the risk of hepatotoxic Duo Plus Tablet of Duo Plus Tablet.

With the simultaneous use of anticoagulants may be slight to moderate increase in prothrombin time.

With the simultaneous use of anticholinergics may decrease absorption of Duo Plus Tablet.

With the simultaneous use of oral contraceptives accelerated excretion of Duo Plus Tablet from the body and may reduce its analgesic Duo Plus Tablet.

With the simultaneous use with urological means reduced their effectiveness.

With the simultaneous use of activated charcoal reduced bioavailability of Duo Plus Tablet.

When Duo Plus Tablet Guardian applied simultaneously with diazepam may decrease excretion of diazepam.

There have been reports about the possibility of enhancing mielodepression effect of zidovudine while applying with Duo Plus Tablet. A case of severe toxic liver injury.

Described cases of toxic effects of Duo Plus Tablet, while the use of isoniazid.

When applied simultaneously with carbamazepine, phenytoin, phenobarbital, primidonom decreases the effectiveness of Duo Plus Tablet, which is caused by an increase in its metabolism and excretion from the body. Cases of hepatotoxicity, while the use of Duo Plus Tablet and phenobarbital.

In applying cholestyramine a period of less than 1 h after administration of Duo Plus Tablet may decrease of its absorption.

At simultaneous application with lamotrigine moderately increased excretion of lamotrigine from the body.

With the simultaneous use of metoclopramide may increase absorption of Duo Plus Tablet and its increased concentration in blood plasma.

When applied simultaneously with probenecid may decrease clearance of Duo Plus Tablet, with rifampicin, sulfinpyrazone - may increase clearance of Duo Plus Tablet due to increasing its metabolism in the liver.

At simultaneous application of Duo Plus Tablet Guardian with ethinylestradiol increases absorption of Duo Plus Tablet from the gut.

Enhances the effect of indirect anticoagulants (coumarin derivatives and indandione). Antipyretic and analgesic activity of caffeine increases, reduce - rifampicin, phenobarbital and alcohol (accelerated biotransformation, inducing microsomal liver enzymes).

Duo Plus Tablet side effects

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What are the possible side effects of Duo Plus Tablet?

Effects due to the presence of acetylsalicylic acid.

Accidents awareness with respiratory or skin reactions (angioedema, urticaria, asthma, anaphylactic shock);

Cross hypersensitivity reactions with NSAIDs and with tartrazine;

At low doses recommended for the use of Duo Plus Tablet, side effects of aspirin are generally limited to some irritation of the gastro-intestinal tract.

At higher doses, side effects include gastrointestinal mucosal erosions, gastric ulcer or duodenal ulcer, occult blood loss, melena.

Acetylsalicylic acid may also increase the tendency to bleeding and bleeding time (the lengthening of bleeding continues 4-6 days after stopping the drug).

It may also worsen renal function including cases of pre-existing condition (the long-term use can cause chronic kidney disease).

The signs of salicylic overdose described under.

Effects due to the presence of Duo Plus Tablet.

At the doses and duration of recommended treatment, side effects are usually negligible, but the prolonged use of Duo Plus Tablet in therapeutic doses large (2-4 g per day, or 10-20 tablets Duo Plus Tablet) may cause the appearance chronic hepatitis. This justifies the recommendations of caution especially in patients with liver disease prior.

Very rarely, it can produce thrombocytopenia.

The acute liver toxicity in overdose massive (doses greater than 8 g of Duo Plus Tablet) is described in paragraph overdose.

Duo Plus Tablet contraindications

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What is the most important information I should know about Duo Plus Tablet?

Duo Plus Tablet should not be used in patients who have previously exhibited hypersensitivity to aspirin and/or nonsteroidal antiinflammatory agents. Duo Plus Tablet should not be given to patients with a recent history of gastrointestinal bleeding or in patients with bleeding disorders (e.g., hemophilia).

Active ingredient matches for Duo Plus Tablet:

Paracetamol


Unit description / dosage (Manufacturer)Price, USD
Duo Plus Tablet$ 0.03

List of Duo Plus Tablet substitutes (brand and generic names):

Duodoase P 500+50+15 Tablet (ORN Remedies Pvt. Ltd.)$ 0.10
Duva CX 325+250+50 Tablet (Dallas Pharmaceuticals)$ 0.04
DVN Forte 80+500 Tablet (Overseas Health Care Pvt. Ltd.)$ 0.09
DVN FORTE 80MG/500MG TABLET 1 strip / 10 tablets each (Overseas Health Care Pvt. Ltd.)$ 1.20
Dvn Forte 80 mg/500 mg Tablet (Overseas Health Care Pvt. Ltd.)$ 0.12
Dykay MR 325+250+50 Tablet (Neo Remedies)$ 0.05
Dykay SP 325+50+10 Tablet (Remedies Pharmaceuticals (India) Ltd.)$ 0.07
Dyklox 325+250+50 Tablet (Medicot Lifesciences)$ 0.07
Dymeclone Plus 20+500 Tablet (Medi Products Pvt.Ltd.)$ 0.02
Dyna P 50+500 Tablet (Santo Formulations)$ 0.03
Dynalid P 100+500 Tablet (Unimax Laboratories)$ 0.03
Dynaparspas 325+50+20 Tablet (Troikaa Parenterals Pvt. Ltd.)$ 0.03
Dyrect P 50+500 Tablet (Ozone Pharmaceuticals Ltd.)$ 0.10
DYRECT P 50 MG/500 MG/10 MG TABLET 1 strip / 10 tablets each (Ozone Pharmaceuticals Ltd.)$ 1.25
Dyrect P 50 mg/500 mg/10 mg Tablet (Ozone Pharmaceuticals Ltd.)$ 0.13
Dyspasm 20+500 Tablet (Chemo Drugs)$ 0.02
Dyspasm 15 ml Drop (Chemo Drugs)$ 0.02
E Dol Plus 500+50 Tablet (Elfin Drugs Pvt. Ltd. (Elfin Pharma Pvt Ltd))$ 0.08
E Fen 50+500 Tablet (Marline Biocare (Zota Healthcare Pvt Ltd))$ 0.02
Eboo 500mg Tablet (Exotic Laboratories Pvt Ltd)$ 0.02
Eboo Plus 500mg Tablet (Exotic Laboratories Pvt Ltd)$ 0.21
Eboo Spaz 500mg Tablet (Exotic Laboratories Pvt Ltd)$ 0.04
EBOO 500 MG TABLET 1 strip / 10 tablets each (Exotic Laboratories Pvt Ltd)$ 0.62
EBOO KID 500 MG TABLET 1 strip / 10 tablets each (Exotic Laboratories Pvt Ltd)$ 0.17
EBOO PLUS 500 MG TABLET 1 strip / 10 tablets each (Exotic Laboratories Pvt Ltd)$ 2.07
EBOO SPAZ 500 MG TABLET 1 strip / 10 tablets each (Exotic Laboratories Pvt Ltd)$ 0.43
Effe-NIC 80 mg x 12 Packs
Effe-NIC 150 mg x 12 Packs
Effebaby 80 mg x 10 Packs x 1.5 g
Effebaby 80 mg x 25 Packs x 1.5 g
Effebaby 150 mg x 10 Packs x 1.5 g
Effebaby 150 mg x 25 Packs x 1.5 g

References

  1. PubChem. "DUO". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. Wikipedia. "4-hydroxy-2,8-dimethyl-1-oxo-6-(4,5,6-trimethoxy-1H-indole-2-carbonyl)-1,2,3,6,7,8-hexahydro-3,6-diaza-as-indacene-2-carboxylic acid methyl ester: Link to the compound information in Wikipedia.". https://www.wikidata.org/wiki/Q27459... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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