Duspatalin PR indications
Irritable bowel syndrome & allied conditions eg, chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Symptomatic treatment of abdominal pain, cramps, nonspecific diarrhoea & flatulence. GI spasm secondary to organic diseases eg, diverticulitis, gastritis, duodenitis, oesophagitis, cholecystitis, Crohn's disease, ulcerative colitis, peptic ulcer, gallbladder disease, hiatus hernia, GIT inflammation.
Uses of Duspatalin PR in details
Duspatalin PR is used to treat irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits). It is also used to treat other conditions that involve spasm and pain related to small and large bowel.
Duspatalin PR description
Each capsule contains Mebeverine HCl 200 mg.
Duspatalin PR also contains the following excipients: Capsule Content (Granules): Magnesium stearate, polyacrylate dispersion 30%, talc, hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30% and glycerol triacetate. Capsule Shell: Gelatin, titanium dioxide (E171). Printing Ink: Shellac (E904), black iron oxide (E172), propylene glycol, concentrated ammonia solution, potassium hydroxide.
Duspatalin PR dosage
Adults: 1 capsule twice daily (1 in the morning and 1 in the evening).
Special Populations: Elderly, Renal and Hepatic Impairment: No posology studies in elderly, renal and/or hepatically impaired patients have been performed. However, no specific risk for elderly, renal and/or hepatically impaired patients could be identified from available post-marketing data. No dosage adjustment is deemed necessary in these patients.
Missed Dose: In case of ≥1 doses missed, continue with the next dose as prescribed; the missed doses are not to be taken in addition to the regular dose.
Administration: The capsules should be swallowed with a sufficient amount of water (at least 100 mL of water).
It should not be chewed because the coating is intended to ensure a prolonged release mechanism.
Duspatalin PR interactions
No interaction studies have been performed except with alcohol. In vitro and in vivo studies in animals have demonstrated the absence of any interaction between Duspatalin PR and ethanol.
Incompatibilities: Not applicable.
Duspatalin PR side effects
Although adverse effects appear rare, gastrointestinal disturbances, dizziness, headache, insomnia, anorexia and tachycardia have been reported in patients receiving Duspatalin PR.
Duspatalin PR contraindications
Hypersensitivity to Duspatalin PR HCl or to any of the excipients of Duspatalin PR.
Active ingredient matches for Duspatalin PR:
Mebeverine in Cyprus.
List of Duspatalin PR substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Duspatalin Retard 200mg (Switzerland) | |
| Duspatin (Thailand) | |
| Duspatin 135 mg x 10 x 10's (Berlin Pharm) | |
| Duspatin tab 135 mg 10 x 10's (Berlin Pharm) | |
| Duspaverin (Turkey) | |
| Equilon (United Kingdom) | |
| Evadol XR (Chile) | |
| Capsule, Prolonged Release; Oral; Mebeverine Hydrochloride 200 mg | |
| Evarin (Bangladesh) | |
| Farlotac (Thailand) | |
| Farlotac tab 135 mg 10 x 10's (Farmaline) | |
| Fibrispa | |
| Fibrispa 135mg Tablet (Fibrica Healthcare Pvt Ltd) | $ 0.12 |
| Fomac (United Kingdom) | |
| Fybogel meberverine (Ireland) | |
| Fybogel Mebeverine (Malta) | |
| Gastromins (Greece) | |
| Gloverine (Pakistan) | |
| IBS Relief (United Kingdom) | |
| Irbosyd (Indonesia) | |
| Irbosyd 135 mg x 30's (Fahrenheit) | $ 9.30 |
| Iriban (Bangladesh) | |
| Iriban-SR (Bangladesh) | |
| Irisyn (Bangladesh) | |
| Lezpain (Malaysia) | |
| Lezpain 135 mg x 10's x 10 (Ysp) | |
| Libure (India) | |
| Libure 135mg TAB / 10 (Aamorb (Sioux)) | $ 0.72 |
| 135 mg x 10's (Aamorb (Sioux)) | $ 0.72 |
| LIBURE tab 135 mg x 10's (Aamorb (Sioux)) | $ 0.76 |
| Manil (Bangladesh) | |
| MATIZ | |
| 7.5 mg x 10's (Gentech HC) | $ 0.51 |
| 15 mg x 10's (Gentech HC) | $ 0.78 |
| 30 mg x 10's (Gentech HC) | $ 1.61 |
| Matiz 7.5mg TAB / 10 (Gentech HC) | $ 0.51 |
| Matiz 15mg TAB / 10 (Gentech HC) | $ 0.78 |
| Matiz 30mg TAB / 10 (Gentech HC) | $ 1.61 |
| MATIZ tab 7.5 mg x 10's (Gentech HC) | $ 0.51 |
| MATIZ tab 15 mg x 10's (Gentech HC) | $ 0.78 |
| MATIZ tab 30 mg x 10's (Gentech HC) | $ 1.61 |
| Matiz 7.5mg TAB / 10 (Gentech HC) | $ 0.51 |
| Matiz 15mg TAB / 10 (Gentech HC) | $ 0.78 |
| Matiz 30mg TAB / 10 (Gentech HC) | $ 1.61 |
| Mave (Bangladesh) | |
| MEB | |
| MEB 200 MG CAPSULE SR 1 strip / 10 capsule srs each (Intas Pharmaceuticals Ltd) | $ 1.14 |
| Meb 200mg Capsule SR (Intas Pharmaceuticals Ltd) | $ 0.13 |
| MEBALFA | |
| MEBALFA 10MG TABLET SR 1 strip / 10 tablet srs each (Torrent Pharmaceuticals Ltd) | $ 1.03 |
| Mebaspa (India) | |
| Mebaspa 135mg TAB / 10 (USV) | $ 0.65 |
| 135 mg x 10's (USV) | $ 0.65 |
See 235 substitutes for Duspatalin PR | |
References
- PubChem. "mebeverine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Mebeverine". http://www.drugbank.ca/drugs/DB12554 (accessed September 17, 2018).
- MeSH. "Parasympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology
