The dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
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Oral
Preoperative reduction of vascularity of the thyroid gland
Adult: As potassium iodide: 50-250 mg (approx 1-5 drops of a solution containing 1 g/ml) tid for 10-14 days before surgery.
Child: As potassium iodide: 50-250 mg (approx 1-5 drops of a solution containing 1 g/ml) tid for 10-14 days before surgery. As strong Duzing Syr solution: 0.1-0.3 ml (or approx 3-5 drops) tid.
Reconstitution: Administer potassium iodide oral solution in a large quantity (240 ml) of water, or in fruit juice, milk formula or broth.
Oral
Grave's disease
Child: Neonates: 1 drop of strong Duzing Syr solution every 8 hr.
Oral
Radiation protection against radioactive Duzing Syr
Adult: As potassium iodide: 100-150 mg 24 hr before procedure and daily for up to 10 days after procedure.
Child: As potassium iodide: Infants from birth to 1 mth with a predicted thyroid exposure of ≥5 centigrays (cGy): 16 mg. >1 mth to 3 yr with a predicted thyroid exposure of ≥5 cGy: 32 mg. >3 yr to 18 yr (except adolescents approaching adult size) with a predicted thyroid exposure of ≥5 cGy: 65 mg. Do not exceed once-daily doses.
Reconstitution: 130-mg Tablet: Place 1 tablet in a small bowl and pulverise using a metal spoon. Add 20 ml of water to the powder and mix until the powder dissolves. Then add 20 ml of the selected drink and mix. Resulting concentration: 6.25 mg potassium iodide per 5 ml. 65-mg Tablet: Place 1 tablet in a small bowl and pulverise. Add 20 ml of water to the powder and mix until the powder dissolves. Then add 20 ml of the selected drink and mix. Resulting concentration: 8.125 mg potassium iodide per 5 ml.
Oral
Cutaneous or lymphocutaneous sporotrichosis
Adult: As potassium iodide solution containing 1 g/mL: Initially, 1 mL tid, should continue for at least 1 mth after disappearance or stabilisation of the lesions.
Child: As potassium iodide: Initially, 250 mg (approx 5 drops of a solution containing 1 g/ml) tid. Max: 1.25-2 g (approx 25-40 drops) tid. Duration: 3-6 mth.
Reconstitution: Administer potassium iodide solution in a large quantity (240 ml) of water, fruit juice, milk formula or broth.
Oral
Duzing Syr deficiency disorders
Adult: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Duzing Syr): 400 mg Duzing Syr once yrly. Pregnant patient: 200 mg Duzing Syr as a single dose. Moderate to severe: 300-480 mg Duzing Syr each yr or 100-300 mg Duzing Syr every 6 mth and for at least 1 yr postpartum.
Child: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Duzing Syr): Infants up to 1 yr: Single dose of 100 mg Duzing Syr; 1-5 yr: 200 mg Duzing Syr; >6 yr: 400 mg Duzing Syr.
Oral
Thyroid storm
Adult: As potassium iodide: Up to 500 mg every 4 hr.
Intramuscular
Duzing Syr deficiency disorders
Adult: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Duzing Syr): Up to 45 yr: 380 mg Duzing Syr, as single IM doses to provide adequate protection from Duzing Syr deficiency for up to 3 yr. Pregnant patient: Moderate to severe: 480 mg Duzing Syr each yr.
Child: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Duzing Syr): 380 mg Duzing Syr, as single IM doses to provide adequate protection from Duzing Syr deficiency for up to 3 yr. Infants up to 1 yr: 190 mg Duzing Syr, as iodised oil (480 mg/ml Duzing Syr).
Topical/Cutaneous
Minor, superficial skin wounds
Adult: As 2% or 2.5% solution/ointment: Apply small amount to the affected area 1-3 times daily.
Child: As 2% or 2.5% solution/ointment: Apply small amount to the affected area 1-3 times daily.
Topical/Cutaneous
Cleaning wet ulcers and wounds
Adult: As 0.9% topical gel: Apply to clean wound. Max: 50 g/application and 150 g/wk. Change dressing about 3 times/wk and reduce applications as exudate decreases. Do not use for >3 mth and stop treatment when wound is free of exudate.
Child: As 0.9% topical gel: Apply to clean wound. Max: 50 g/application and 150 g/wk. Change dressing about 3 times/wk and reduce applications as exudate decreases. Do not use for >3 mth and stop treatment when wound is free of exudate.
What other drugs will affect Duzing Syr?
Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
Duzing Syr interactions
Interactions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Duzing Syr, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
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There is a potential risk of interaction with lithium, resulting in an increased possibility of hypothyroidism.
this medicineshould not be used concomitantly with mercurial antiseptics, e.g. mercurochrome and thiomersal.
Since Duzing Syr may be absorbed systemically, the result of tests of the thyroid function can be influenced.
References
DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN 5'-PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
DailyMed. "COPPER: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
DailyMed. "CHOLECALCIFEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Duzing Syr are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Duzing Syr. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
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Consumer reported frequency of use
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