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Duzing Syr Dosage |
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Preoperative reduction of vascularity of the thyroid gland
Adult: As potassium iodide: 50-250 mg (approx 1-5 drops of a solution containing 1 g/ml) tid for 10-14 days before surgery.
Child: As potassium iodide: 50-250 mg (approx 1-5 drops of a solution containing 1 g/ml) tid for 10-14 days before surgery. As strong Duzing Syr solution: 0.1-0.3 ml (or approx 3-5 drops) tid.
Reconstitution: Administer potassium iodide oral solution in a large quantity (240 ml) of water, or in fruit juice, milk formula or broth.
Grave's disease
Child: Neonates: 1 drop of strong Duzing Syr solution every 8 hr.
Radiation protection against radioactive Duzing Syr
Adult: As potassium iodide: 100-150 mg 24 hr before procedure and daily for up to 10 days after procedure.
Child: As potassium iodide: Infants from birth to 1 mth with a predicted thyroid exposure of ≥5 centigrays (cGy): 16 mg. >1 mth to 3 yr with a predicted thyroid exposure of ≥5 cGy: 32 mg. >3 yr to 18 yr (except adolescents approaching adult size) with a predicted thyroid exposure of ≥5 cGy: 65 mg. Do not exceed once-daily doses.
Reconstitution: 130-mg Tablet: Place 1 tablet in a small bowl and pulverise using a metal spoon. Add 20 ml of water to the powder and mix until the powder dissolves. Then add 20 ml of the selected drink and mix. Resulting concentration: 6.25 mg potassium iodide per 5 ml. 65-mg Tablet: Place 1 tablet in a small bowl and pulverise. Add 20 ml of water to the powder and mix until the powder dissolves. Then add 20 ml of the selected drink and mix. Resulting concentration: 8.125 mg potassium iodide per 5 ml.
Cutaneous or lymphocutaneous sporotrichosis
Adult: As potassium iodide solution containing 1 g/mL: Initially, 1 mL tid, should continue for at least 1 mth after disappearance or stabilisation of the lesions.
Child: As potassium iodide: Initially, 250 mg (approx 5 drops of a solution containing 1 g/ml) tid. Max: 1.25-2 g (approx 25-40 drops) tid. Duration: 3-6 mth.
Reconstitution: Administer potassium iodide solution in a large quantity (240 ml) of water, fruit juice, milk formula or broth.
Duzing Syr deficiency disorders
Adult: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Duzing Syr): 400 mg Duzing Syr once yrly. Pregnant patient: 200 mg Duzing Syr as a single dose. Moderate to severe: 300-480 mg Duzing Syr each yr or 100-300 mg Duzing Syr every 6 mth and for at least 1 yr postpartum.
Child: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Duzing Syr): Infants up to 1 yr: Single dose of 100 mg Duzing Syr; 1-5 yr: 200 mg Duzing Syr; >6 yr: 400 mg Duzing Syr.
Thyroid storm
Adult: As potassium iodide: Up to 500 mg every 4 hr.
Duzing Syr deficiency disorders
Adult: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Duzing Syr): Up to 45 yr: 380 mg Duzing Syr, as single IM doses to provide adequate protection from Duzing Syr deficiency for up to 3 yr. Pregnant patient: Moderate to severe: 480 mg Duzing Syr each yr.
Child: As iodised oil (poppyseed/peanut/rapeseed oil containing about 38% w/w or 480 mg/ml of Duzing Syr): 380 mg Duzing Syr, as single IM doses to provide adequate protection from Duzing Syr deficiency for up to 3 yr. Infants up to 1 yr: 190 mg Duzing Syr, as iodised oil (480 mg/ml Duzing Syr).
Minor, superficial skin wounds
Adult: As 2% or 2.5% solution/ointment: Apply small amount to the affected area 1-3 times daily.
Child: As 2% or 2.5% solution/ointment: Apply small amount to the affected area 1-3 times daily.
Cleaning wet ulcers and wounds
Adult: As 0.9% topical gel: Apply to clean wound. Max: 50 g/application and 150 g/wk. Change dressing about 3 times/wk and reduce applications as exudate decreases. Do not use for >3 mth and stop treatment when wound is free of exudate.
Child: As 0.9% topical gel: Apply to clean wound. Max: 50 g/application and 150 g/wk. Change dressing about 3 times/wk and reduce applications as exudate decreases. Do not use for >3 mth and stop treatment when wound is free of exudate.
Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
There is a potential risk of interaction with lithium, resulting in an increased possibility of hypothyroidism.
this medicineshould not be used concomitantly with mercurial antiseptics, e.g. mercurochrome and thiomersal.
Since Duzing Syr may be absorbed systemically, the result of tests of the thyroid function can be influenced.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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