What happens if I overdose Emadrin?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately. Symptoms may include dilated pupils; fast breathing; fast heartbeat; hot, dry, or flushed skin.
Proper storage of Emadrin:
Store Emadrin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Emadrin out of the reach of children and away from pets.
Overdose of Emadrin in details
Symptoms: Stimulant effects (e.g. agitation, restlessness, confusion, sleeplessness lasting up to ≥24 hr; euphoria, anxiety, aggressive behaviour; dilated pupils that are nonreactive to light; disorientation (lasting for 1-4 days); CNS depression (e.g. somnolence, reduced consciousness, and occasionally coma); tachycardia. Management: Use activated charcoal to reduce absorption w/in 1-2 hr of ingestion (or possibly longer in view of its likely effects on gastric motility). Consider gastric lavage only if clinically appropriate. May give diazepam inj if convulsions occur.
What should I avoid while taking Emadrin?
Use caution when driving, operating machinery, or performing other hazardous activities. Emadrin may cause dizziness or blurred vision. If you experience dizziness or blurred vision, avoid these activities.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Emadrin.
Avoid becoming overheated. Emadrin may cause decreased sweating. This could lead to heat stroke in hot weather or with vigorous exercise. Try to keep as cool as possible and watch for signs of heat stroke such as decreased sweating, nausea, and dizziness.
Emadrin warnings
Use in Children: Safety and efficacy have not been established in the pediatric age group; therefore, the use of Emadrin hydrochloride in this age group requires that the potential benefits be weighed against the possible hazards to the child.
Pregnancy Warning
The safe use of this drug in pregnancy has not been established; therefore, the use of Emadrin hydrochloride in pregnancy, lactation, or in women of childbearing age requires that the potential benefits be weighed against the possible hazards to the mother and child.
What should I discuss with my healthcare provider before taking Emadrin?
Some medical conditions may interact with Emadrin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have glaucoma, mental or mood disorders, muscle weakness (eg, myasthenia gravis), ulcerative colitis, (eg, an enlarged prostate), or urination problems
- if you have a blockage of the stomach, esophagus, or urinary tract; kidney or liver problems; high blood pressure; heart or blood vessel disease; an irregular heartbeat; or uncontrolled movements of the hands, mouth, or tongue
Some MEDICINES MAY INTERACT with Emadrin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Phenothiazines (eg, thioridazine) because the effectiveness may be decreased by Emadrin
This may not be a complete list of all interactions that may occur. Ask your health care provider if Emadrin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Emadrin precautions
Conditions in which inhibition of the parasympathetic nervous system is undesirable, such as tachycardia and urinary retention (such as may occur with marked prostatic hypertrophy), require special care in the administration of the drug. Hypotensive patients who receive the drug should be observed closely. Occasionally, particularly in older patients, mental confusion and disorientation may occur with the development of agitation, hallucinations, and psychotic-like symptoms. Patients with mental disorders occasionally experience a precipitation of a psychotic episode when the dosage of antiparkinsonism drugs is increased to treat the extrapyramidal side effects of phenothiazine and rauwolfia derivatives.
Geriatric Use
Clinical studies of Emadrin did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should start at the low end of the dosing range and the dose should be increased only as needed with monitoring for the emergence of adverse events.
What happens if I miss a dose of Emadrin?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and only take your next regularly scheduled dose. Do not take a double dose of this medication.
References
- DrugBank. "procyclidine". http://www.drugbank.ca/drugs/DB00387 (accessed September 17, 2018).
- MeSH. "Muscarinic Antagonists". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
