Endure Medical Hydralazine HCl Uses

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What is Endure Medical Hydralazine HCl?

Endure Medical Hydralazine HCl is used to treat high blood pressure (hypertension). It is also used to control high blood pressure in a mother during pregnancy (pre-eclampsia or eclampsia) or in emergency situations when blood pressure is extremely high (hypertensive crisis).

High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can increase the risk of heart attacks and strokes.

Endure Medical Hydralazine HCl works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload.

Endure Medical Hydralazine HCl is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not specifically included in product labeling, Endure Medical Hydralazine HCl is used in certain patients with the following medical condition:

Endure Medical Hydralazine HCl indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Oral: Hypertension,


Hypertensive crisis

How should I use Endure Medical Hydralazine HCl?

Use Endure Medical Hydralazine HCl as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Endure Medical Hydralazine HCl.

Uses of Endure Medical Hydralazine HCl in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Endure Medical Hydralazine HCl is used with or without other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Endure Medical Hydralazine HCl is called a vasodilator. It works by relaxing blood vessels so blood can flow through the body more easily.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

Endure Medical Hydralazine HCl may also be used with other medications to treat heart failure.

How to use Endure Medical Hydralazine HCl

Take this medication by mouth with or without food, usually 2 to 4 times daily or as directed by your doctor. The dosage is based on your medical condition and response to treatment. Your doctor may start you at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may take up to several weeks before you get the full benefit of this drug.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Tell your doctor if your condition worsens (for example, your routine blood pressure readings increase).

Endure Medical Hydralazine HCl description


A direct-acting vasodilator that is used as an antihypertensive agent. [PubChem]

Endure Medical Hydralazine HCl dosage

50-200 mg depending on indication.

Endure Medical Hydralazine HCl interactions

See also:
What other drugs will affect Endure Medical Hydralazine HCl?

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine).

Check the labels on all your medicines (such as cough-and-cold products, diet aids, or NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that could increase your blood pressure/heart rate or worsen your heart failure. Ask your pharmacist about using those products safely.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Endure Medical Hydralazine HCl side effects

See also:
What are the possible side effects of Endure Medical Hydralazine HCl?


Headache, pounding/fast heartbeat, loss of appetite, nausea, vomiting, diarrhea, or dizziness may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may rarely cause nerve problems. Tell your doctor promptly if you experience numbness or tingling. Your doctor may recommend a vitamin B6 supplement (pyridoxine).

Tell your doctor right away if any of these unlikely but serious side effects occur: severe tiredness, aching/swollen joints, rash on nose and cheeks, swollen glands, signs of kidney problems (such as change in the amount of urine, bloody/pink urine), signs of infection (such as fever, chills, persistent sore throat), easy bruising/bleeding.

Seek immediate medical attention if this rare but serious side effect occurs: chest/jaw/left arm pain.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Endure Medical Hydralazine HCl contraindications

See also:
What is the most important information I should know about Endure Medical Hydralazine HCl?

Idiopathic SLE & related diseases. Severe tachycardia & heart failure w/ high cardiac output. Myocardial insufficiency due to mechanical obstruction. Isolated right ventricular heart failure due to pulmonary HTN. Dissecting aortic aneurysm.

Active ingredient matches for Endure Medical Hydralazine HCl:

Hydralazine HCl in Philippines.

List of Endure Medical Hydralazine HCl substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD
Adernan 50 mg x 1000's
Aprezin Tab 10 mg x 100's
Aprezin Tab 25 mg x 100's
Hydralazine Beacons 10 mg x 1's
Hydralazine Beacons 50 mg x 1000's
Hydralazine DHA 10 mg x 1's
Hydralazine Dragees T.O. 50 mg x 500's (T. O. Chemicals)
Hydralazine Dragees T.O. 50 mg x 50 x 10's (T. O. Chemicals)
Hydralazine Dragees T.O. tab 50 mg 50 x 10's (T. O. Chemicals)
Hydralazine Dragees T.O. tab 50 mg 500's (T. O. Chemicals)
Hydralazine HCl Par 10 mg x 100's
Hydralazine HCl Par 10 mg x 1, 000's
Hydralazine HCl Par 25 mg x 100's
Hydralazine HCl Par 25 mg x 1, 000's
Hydralazine HCl Par 50 mg x 100's
Hydralazine HCl Par 50 mg x 1, 000's


  1. PubChem. "hydralazine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "hydralazine". http://www.drugbank.ca/drugs/DB01275 (accessed September 17, 2018).
  3. DTP/NCI. "hydralazine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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