What happens if I overdose Endure Medical Hydralazine HCl?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest pain; fast or irregular heartbeat; flushing; severe headache; shock.
Proper storage of Endure Medical Hydralazine HCl:
Endure Medical Hydralazine HCl is usually handled and stored by a health care provider. If you are using Endure Medical Hydralazine HCl at home, store Endure Medical Hydralazine HCl as directed by your pharmacist or health care provider. Keep Endure Medical Hydralazine HCl out of the reach of children and away from pets.
Overdose of Endure Medical Hydralazine HCl in details
When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting, flushing, chest/jaw/left arm pain, irregular heartbeat.
Notes
Do not share this medication with others.
Lifestyle changes such as stress reduction programs, exercise, and dietary changes may help this medication work better. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.
Laboratory and/or medical tests (such as complete blood count) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Have your blood pressure checked regularly while taking this medication. Learn how to monitor your own blood pressure, and share the readings with your doctor.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Storage
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
What should I avoid while taking Endure Medical Hydralazine HCl?
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Endure Medical Hydralazine HCl warnings
Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
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Cerebrovascular disorders. Ischaemic heart disease. Hepatic or renal impairment. May deplete pyridoxine in the body. May impair ability to drive or operate machinery. Monitor for postural hypotension if given to patients with heart failure. Withdraw gradually. CBC and antinuclear antibody tests should be carried out every 6 mth during long-term therapy. Urine analysis is also recommended. Pregnancy and lactation. Daily doses >100 mg may increase the risk of SLE especially in women and slow acetylators. Pregnancy category C
What should I discuss with my healthcare provider before taking Endure Medical Hydralazine HCl?
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For Endure Medical Hydralazine HCl, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to Endure Medical Hydralazine HCl or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies on the relationship of age to the effects of Endure Medical Hydralazine HCl have not been performed in the pediatric population. However, no pediatric-specific problems have been documented to date.
Geriatric
No information is available on the relationship of age to the effects of Endure Medical Hydralazine HCl in geriatric patients.
Pregnancy
Pregnancy Category
Explanation
All Trimesters
C
Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
Breast Feeding
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using Endure Medical Hydralazine HCl with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use Endure Medical Hydralazine HCl, or give you special instructions about the use of food, alcohol, or tobacco.
Enteral Nutrition
food
Other Medical Problems
The presence of other medical problems may affect the use of Endure Medical Hydralazine HCl. Make sure you tell your doctor if you have any other medical problems, especially:
Angina (severe chest pain) or
Blood disease or
Heart attack, history of or
Heart rhythm problems or
Hypotension (low blood pressure) or
Peripheral neuritis (nerve problem) or
Stroke, history of or
Systemic lupus erythematosus—Use with caution. May make these conditions worse.
Coronary artery disease or
Mitral valvular rheumatic heart disease—Should not be used in patients with these conditions.
Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Phenylketonuria—The oral solution contains aspartame, which can make this condition worse.
Endure Medical Hydralazine HCl precautions
Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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Before taking Endure Medical Hydralazine HCl, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain heart condition (coronary artery disease), a certain heart valve problem (rheumatic heart disease of the mitral valve).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood vessel problems, previous stroke, kidney problems.
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
Before having surgery, tell your doctor or dentist that you are taking this medication.
Older adults may be more sensitive to the side effects of this medication, especially dizziness, which can increase the risk of falls.
This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
This medication passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
What happens if I miss a dose of Endure Medical Hydralazine HCl?
When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
NITE-CMC. "Hydralazine: The chemical classification in this section was conducted by the Chemical Management Center (CMC) of Japan National Institute of Technology and Evaluation (NITE) in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.". http://www.safe.nite.go.jp/english/g... (accessed September 17, 2018).
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