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Erythromycin 250MG TABLET Pregnancy |
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Erythromycin 250MG TABLET crosses the placenta in small amounts. In one study of 11 patients who had detectable Erythromycin 250MG TABLET levels in the serum, 4 infants did not have detectable cord concentrations. The cord concentrations in the remaining 7 infants generally ranged from 1% to 6% of that found in maternal serum. A case of left absence-of-tibia syndrome was reported in an infant whose mother had received Erythromycin 250MG TABLET, ethisterone, and ethinyl estradiol at approximately 4 weeks gestation. Erythromycin 250MG TABLET has been used prior to delivery in women colonized with group B beta-hemolytic streptococcus to reduce infant colonization. No adverse events in the infants have been reported. Erythromycin 250MG TABLET has also been used to treat genital Mycoplasma infection during the first trimester without evidence of fetal adverse effects. Pregnant women receiving Erythromycin 250MG TABLET estolate may be more prone to hepatotoxicity. In one study of women receiving Erythromycin 250MG TABLET estolate between the 22nd and 32nd week of pregnancy, 10% showed abnormal levels of SGOT.
Erythromycin 250MG TABLET has been assigned to pregnancy category B by the FDA. Animal studies failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. The Centers for Disease Control and Prevention considers Erythromycin 250MG TABLET the drug of choice for treatment of Chlamydia infections in pregnant women. However, Erythromycin 250MG TABLET estolate is considered contraindicated because of drug-related hepatotoxicity. Erythromycin 250MG TABLET should only be given during pregnancy when need has been clearly established.
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Erythromycin 250MG TABLET is excreted into human milk in small amounts. Erythromycin 250MG TABLET is considered compatible with breast-feeding by the American Academy of Pediatrics.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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