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Erythromycin Central Procurement Pregnancy |
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Erythromycin Central Procurement crosses the placenta in small amounts. In one study of 11 patients who had detectable Erythromycin Central Procurement levels in the serum, 4 infants did not have detectable cord concentrations. The cord concentrations in the remaining 7 infants generally ranged from 1% to 6% of that found in maternal serum. A case of left absence-of-tibia syndrome was reported in an infant whose mother had received Erythromycin Central Procurement, ethisterone, and ethinyl estradiol at approximately 4 weeks gestation. Erythromycin Central Procurement has been used prior to delivery in women colonized with group B beta-hemolytic streptococcus to reduce infant colonization. No adverse events in the infants have been reported. Erythromycin Central Procurement has also been used to treat genital Mycoplasma infection during the first trimester without evidence of fetal adverse effects. Pregnant women receiving Erythromycin Central Procurement estolate may be more prone to hepatotoxicity. In one study of women receiving Erythromycin Central Procurement estolate between the 22nd and 32nd week of pregnancy, 10% showed abnormal levels of SGOT.
Erythromycin Central Procurement has been assigned to pregnancy category B by the FDA. Animal studies failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. The Centers for Disease Control and Prevention considers Erythromycin Central Procurement the drug of choice for treatment of Chlamydia infections in pregnant women. However, Erythromycin Central Procurement estolate is considered contraindicated because of drug-related hepatotoxicity. Erythromycin Central Procurement should only be given during pregnancy when need has been clearly established.
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Erythromycin Central Procurement is excreted into human milk in small amounts. Erythromycin Central Procurement is considered compatible with breast-feeding by the American Academy of Pediatrics.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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