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Erythromycin Delayed-Release Particles Capsules Pregnancy |
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Erythromycin Delayed-Release Particles Capsules crosses the placenta in small amounts. In one study of 11 patients who had detectable Erythromycin Delayed-Release Particles Capsules levels in the serum, 4 infants did not have detectable cord concentrations. The cord concentrations in the remaining 7 infants generally ranged from 1% to 6% of that found in maternal serum. A case of left absence-of-tibia syndrome was reported in an infant whose mother had received Erythromycin Delayed-Release Particles Capsules, ethisterone, and ethinyl estradiol at approximately 4 weeks gestation. Erythromycin Delayed-Release Particles Capsules has been used prior to delivery in women colonized with group B beta-hemolytic streptococcus to reduce infant colonization. No adverse events in the infants have been reported. Erythromycin Delayed-Release Particles Capsules has also been used to treat genital Mycoplasma infection during the first trimester without evidence of fetal adverse effects. Pregnant women receiving Erythromycin Delayed-Release Particles Capsules estolate may be more prone to hepatotoxicity. In one study of women receiving Erythromycin Delayed-Release Particles Capsules estolate between the 22nd and 32nd week of pregnancy, 10% showed abnormal levels of SGOT.
Erythromycin Delayed-Release Particles Capsules has been assigned to pregnancy category B by the FDA. Animal studies failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. The Centers for Disease Control and Prevention considers Erythromycin Delayed-Release Particles Capsules the drug of choice for treatment of Chlamydia infections in pregnant women. However, Erythromycin Delayed-Release Particles Capsules estolate is considered contraindicated because of drug-related hepatotoxicity. Erythromycin Delayed-Release Particles Capsules should only be given during pregnancy when need has been clearly established.
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Erythromycin Delayed-Release Particles Capsules is excreted into human milk in small amounts. Erythromycin Delayed-Release Particles Capsules is considered compatible with breast-feeding by the American Academy of Pediatrics.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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