Estelle-35 ED Actions

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Actions of Estelle-35 ED in details

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Pharmacotherapeutic Group:

Oral contraceptive.

Estelle-35 ED is a progestogen-only oral contraceptive pill. Progestogens are derived from the natural hormone progesterone or 19-nortestosterone, which actions are similar to those of progesterone.

Mechanism of Action: Estelle-35 ED works primarily by thickening cervical mucus (this blocks sperm from meeting an egg) and disrupting the menstrual cycle, including preventing the release of eggs from the ovaries (ovulation).

Estelle-35 ED is safe to use by breastfeeding mothers.

Pharmacokinetics: Progesterone, like Estelle-35 ED, has a short elimination t½ and undergoes extensive first-pass hepatic metabolism when taken orally. The oral bioavailability is very low but may be increased by an oily vehicle and micronization.

References

  1. NCIt. "Cyproterone Acetate: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
  2. EPA DSStox. "Cyproterone acetate: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).

Reviews

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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