Farmavon SYRUP indicated for cough associated with wheeziness (bronchospasm) and tenacious phlegm (sputum).
Farmavon is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.
Each tablet also contains lactose, maize or potato starch, gelatine and magnesium stearate as excipients.
The oral/inhalation solution also contains tartaric acid and methyl parahydroxybenzoate as excipients.
The syrup also contains tartaric acid, benzoic acid, sodium carboxymethylcellulose, glycerol, sorbitol solution, pharma flavor and ethanol as excipients.
Each capsule also contains lactose, cornstarch and magnesium stearate as excipients.
Farmavon is N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrochloride.
Unless otherwise prescribed, the following doses are recommended:
Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.
Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.
Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.
The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.
Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.
At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.
The syrup is sugar-free and therefore suitable for diabetics and small children.
Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.
Capsule: Adults: 1 cap 3 times daily.
It is recommended for the initial phase of treatment usually lasting not more than a week.
Patients being treated with Farmavon should be notified of an expected increase in the flow of secretions.
A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.
Farmavon SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.
The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.
Farmavon’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Farmavon.
Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.
Farmavon SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.
Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Farmavon SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.
Safety in pregnancy and lactation has not been established.
Bromhexine in Indonesia.
Bromhexine HCl in Indonesia.
Bromhexine hydrochloride in Indonesia.
|Unit description / dosage (Manufacturer)||Price, USD|
|Farmavon 8 mg x 10 x 10's||$ 4.09|
|Farmavon 4 mg/1 mL x 125 mL x 1's||$ 1.86|
List of Farmavon substitutes (brand and generic names):
|Famel Broomhexine (Netherlands)|
|Fei Li Xing (China)|
|Flamolyte 8 mg x 10 Blister x 10 Tablet|
|Flecoxin (Bahrain, Cyprus, Ghana, Kenya, Malta, Oman, Taiwan, Tanzania)|
|Flecoxin 4mg (Oman)|
|Flegamina Baby (Poland)|
|Flegamina Junior (Poland)|
|Fleminate 16 mg x 100's (Novo pharm)||$ 13.33|
|Fleminate 4 mg/5 mL x 60 mL (Novo pharm)||$ 1.00|
|Flu-4 DPS (India)|
|Flu-4 DPS Paracetamol 125 mg, Phenylephrine hydrochloride2.5 mg, Chlorpheniraminemaleate 1 mg, Bromhexine 2 mg. DPS / 15ml (Haledew)||$ 0.43|
|15ml (Haledew)||$ 0.43|
|FLU-4 DPS oral drops 15ml (Haledew)||$ 0.43|
|Fluibron (Brazil, Chile, Cyprus, Egypt, Italy, Jordan, Kuwait, Lebanon, Peru, Saudi Arabia, Syria, Turkey)|
|Syrup; Oral; Ambroxol Hydrochloride 15 mg / 5 ml (Andromaco)|
|Syrup; Oral; Ambroxol Hydrochloride 30 mg / 5 ml (Andromaco)|
|Flukuff Dextromethorphan 10 mg, guaiphenesin 100 mg, bromhexine 8 mg, chlorpheniramine maleate 2 mg. TAB / 10 (Intas Laboratories Pvt Ltd)||$ 0.46|
|Flukuff 60 ml Syrup (Intas Laboratories Pvt Ltd)||$ 0.04|
|FLUKUFF tab 10's (Intas Laboratories Pvt Ltd)||$ 0.46|
|Flutox Forte (Chile)|
|Fu Zhi (China)|
|Fucole Bislan (Taiwan)|
|Fucole Bislan 12 mg|
|Fulpen A (Japan)|
|Funciobron B (Argentina)|
|Gadovital Forte (Ecuador)|
|GDC Tablet (Lexicon Biotech (India) Ltd)||$ 0.04|
|Glam BR 250 mg Tablet (Gladcare)||$ 0.07|
|Glam BR 500 mg Tablet (Gladcare)||$ 0.13|
|Gluventin 8 mg|
|Glycofex Tablet (Glyco Labs.)||$ 0.07|
|Go Kuff 100 ml Syrup (Uniword Marketing (P) Ltd)||$ 0.02|
|Gocough 100 ml Syrup (Ultramark Healthcare Pvt Ltd.)||$ 0.08|
|Grilinctus BM 30 ml Syrup (Franco Indian Remedies)||$ 0.05|
|Grilinctus BM 2.5+8 Tablet (Franco Indian Remedies)||$ 0.01|
|Grilinctus BM 100 ml Syrup (Franco Indian Remedies)||$ 0.03|
|GRILINCTUS BM 2.5 MG/8 MG SYRUP 1 bottle / 100 ML syrup each (Franco Indian Remedies)||$ 1.05|
|GRILINCTUS BM 2.5 MG/8 MG TABLET 1 strip / 10 tablets each (Franco Indian Remedies)||$ 0.18|
|GRILINCTUS BM PD SYRUP 1 bottle / 30 ML syrup each (Franco Indian Remedies)||$ 0.48|
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Information checked by Dr. Sachin Kumar, MD Pharmacology