Farmavon Uses

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Farmavon indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Farmavon SYRUP indicated for cough associated with wheeziness (bronchospasm) and tenacious phlegm (sputum).

Uses of Farmavon in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Farmavon is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.

Farmavon description

Each tablet also contains lactose, maize or potato starch, gelatine and magnesium stearate as excipients.

The oral/inhalation solution also contains tartaric acid and methyl parahydroxybenzoate as excipients.

The syrup also contains tartaric acid, benzoic acid, sodium carboxymethylcellulose, glycerol, sorbitol solution, pharma flavor and ethanol as excipients.

Each capsule also contains lactose, cornstarch and magnesium stearate as excipients.

Farmavon is N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrochloride.

Farmavon dosage

Unless otherwise prescribed, the following doses are recommended:

Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.

Oral Solution:

Adults and Children >12 years: 4 mL thrice daily; 6-12 years: 2 mL thrice daily; 2-6 years: 20 drops thrice daily; <2 years: 10 drops thrice daily.

Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.

Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.

The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.

Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.

At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.

The syrup is sugar-free and therefore suitable for diabetics and small children.

Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.

Capsule: Adults: 1 cap 3 times daily.

It is recommended for the initial phase of treatment usually lasting not more than a week.

Patients being treated with Farmavon should be notified of an expected increase in the flow of secretions.

Farmavon interactions

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A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.

Farmavon SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.

The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.

Farmavon side effects

Farmavon’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Farmavon.

Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.

Farmavon contraindications

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Farmavon SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.

Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Farmavon SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.

Safety in pregnancy and lactation has not been established.

Active ingredient matches for Farmavon:

Bromhexine in Indonesia.

Bromhexine HCl in Indonesia.

Bromhexine hydrochloride in Indonesia.


Unit description / dosage (Manufacturer)Price, USD
Farmavon 8 mg x 10 x 10's$ 4.09
Farmavon 4 mg/1 mL x 125 mL x 1's$ 1.86

List of Farmavon substitutes (brand and generic names):

Flamolyte 8 mg x 10 Blister x 10 Tablet
Fleminate 16 mg x 100's (Novo pharm)$ 13.33
Fleminate 4 mg/5 mL x 60 mL (Novo pharm)$ 1.00
Flu-4 DPS Paracetamol 125 mg, Phenylephrine hydrochloride2.5 mg, Chlorpheniraminemaleate 1 mg, Bromhexine 2 mg. DPS / 15ml (Haledew)$ 0.43
15ml (Haledew)$ 0.43
FLU-4 DPS oral drops 15ml (Haledew)$ 0.43
Syrup; Oral; Ambroxol Hydrochloride 15 mg / 5 ml (Andromaco)
Syrup; Oral; Ambroxol Hydrochloride 30 mg / 5 ml (Andromaco)
Flukuff Dextromethorphan 10 mg, guaiphenesin 100 mg, bromhexine 8 mg, chlorpheniramine maleate 2 mg. TAB / 10 (Intas Laboratories Pvt Ltd)$ 0.46
Flukuff 60 ml Syrup (Intas Laboratories Pvt Ltd)$ 0.04
FLUKUFF tab 10's (Intas Laboratories Pvt Ltd)$ 0.46
Fucole Bislan 12 mg
GDC Tablet (Lexicon Biotech (India) Ltd)$ 0.04
Glam BR 250 mg Tablet (Gladcare)$ 0.07
Glam BR 500 mg Tablet (Gladcare)$ 0.13
Gluventin 8 mg
Glycofex Tablet (Glyco Labs.)$ 0.07
Go Kuff 100 ml Syrup (Uniword Marketing (P) Ltd)$ 0.02
Gocough 100 ml Syrup (Ultramark Healthcare Pvt Ltd.)$ 0.08
Grilinctus BM 30 ml Syrup (Franco Indian Remedies)$ 0.05
Grilinctus BM 2.5+8 Tablet (Franco Indian Remedies)$ 0.01
Grilinctus BM 100 ml Syrup (Franco Indian Remedies)$ 0.03
GRILINCTUS BM 2.5 MG/8 MG SYRUP 1 bottle / 100 ML syrup each (Franco Indian Remedies)$ 1.05
GRILINCTUS BM 2.5 MG/8 MG TABLET 1 strip / 10 tablets each (Franco Indian Remedies)$ 0.18
GRILINCTUS BM PD SYRUP 1 bottle / 30 ML syrup each (Franco Indian Remedies)$ 0.48

References

  1. PubChem. "bromhexine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Bromhexine". http://www.drugbank.ca/drugs/DB09019 (accessed September 17, 2018).
  3. MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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