Consists of ferrous ascorbate, folic acid
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Ferix-XT Pregnancy |
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Consists of ferrous ascorbate, folic acid
Folic acid (Ferix-XT) has been assigned to pregnancy category A by the FDA. During pregnancy, Folic acid (Ferix-XT) is usually used for the treatment of megaloblastic anemia. Folic acid (Ferix-XT) requirements are increased during pregnancy, and deficiency may result in fetal harm. Studies involving pregnant women have failed to reveal evidence that Folic acid (Ferix-XT) increases the risk of fetal abnormalities if administered during pregnancy. Folic acid (Ferix-XT) should only be used during pregnancy if clearly needed.
The recommended daily allowance of Folic acid (Ferix-XT) during pregnancy is 400 to 800 mcg/day. Some experts recommend daily doses of 1 mg for twin pregnancies. The Centers of Disease Control (CDC) in the US have recommended 4 mg/day of Folic acid (Ferix-XT) at least 4 weeks BEFORE conception through the first 3 months of pregnancy for women who have had an infant or fetus with a neural tube defect and 400 mcg/day for all women of childbearing age. Interestingly, neonates with normal serum folate concentrations have been born to folate-deficient mothers. It appears that the fetus can extract folate from maternal plasma, convert folate to a form that is not available for reverse transfer, and use it for its own advantage. Dietary Folic acid (Ferix-XT) is available from green leaves, such as asparagus, broccoli, spinach, and lettuce--each of which contains greater than 1 mg Folic acid (Ferix-XT) per 100 grams dry weight. Excessive cooking can remove or destroy the food content of folate.
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In one study, lactating mothers were given 1 mg of Folic acid (Ferix-XT) per day. There were significant correlations between the maternal and infant plasma and RBC folate concentrations. The average maternal plasma Folic acid (Ferix-XT) concentration was 5.9 ng/mL, which correlated with an average milk Folic acid (Ferix-XT) level of 141.4 ng/mL and an average infant plasma Folic acid (Ferix-XT) concentration of 29 ng/mL. The calculated total intake of Folic acid (Ferix-XT) by nursing infants was 14 to 25 mcg/kg/day. Colostrum is relatively low in folate, but milk folate increases as lactation proceeds. Folate levels in breast-fed infants are significantly higher than in the mothers.
Folic acid (Ferix-XT) is actively excreted into human milk. No adverse effects in nursing infants have been associated with the use of Folic acid (Ferix-XT) during lactation. Folic acid (Ferix-XT) is considered compatible with breast-feeding by the American Academy of Pediatrics. The recommended maternal daily allowance of Folic acid (Ferix-XT) during lactation is 500 mcg. Supplementation is not typically needed in mothers with good nutritional habits.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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