Ferograd 525mg/500mg Uses

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What is Ferograd 525mg/500mg?

Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Ferograd 525mg/500mg (vitamin B 9) is necessary for strong blood.

Lack of Ferograd 525mg/500mg may lead to anemia (weak blood). Your health care professional may treat this by prescribing Ferograd 525mg/500mg for you.

Some conditions may increase your need for Ferograd 525mg/500mg. These include:

In addition, infants smaller than normal, breast-fed infants, or those receiving unfortified formulas (such as evaporated milk or goat's milk) may need additional Ferograd 525mg/500mg.

Increased need for Ferograd 525mg/500mg should be determined by your health care professional.

Some studies have found that Ferograd 525mg/500mg taken by women before they become pregnant and during early pregnancy may reduce the chances of certain birth defects (neural tube defects).

Claims that Ferograd 525mg/500mg and other B vitamins are effective for preventing mental problems have not been proven. Many of these treatments involve large and expensive amounts of vitamins.

Injectable Ferograd 525mg/500mg is given by or under the direction of your health care professional. Another form of Ferograd 525mg/500mg is available without a prescription.

Ferograd 525mg/500mg indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Ferograd 525mg/500mg is used in the treatment and prevention of the folate deficiency state. It does not correct folate deficiency due to dihydrofolate reductase inhibitors. Ferograd 525mg/500mg is also used in women of child-bearing potential and pregnant women to protect against neural tube defects in their offspring. It is also used for the treatment of folate-deficient megaloblastic anaemia, chronic haemolytic states such as thalassaemia major or sickle-cell anaemia.

How should I use Ferograd 525mg/500mg?

Use Ferograd 525mg/500mg as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Ferograd 525mg/500mg.

Uses of Ferograd 525mg/500mg in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Ferograd 525mg/500mg is the man-made form of folate. Folate is a B-vitamin naturally found in some foods. It is needed to form healthy cells, especially red blood cells.

Ferograd 525mg/500mg supplements may come in different forms (such as L-methylfolate, levomefolate, methyltetrahydrofolate). They are used to treat or prevent low folate levels. Low folate levels can lead to certain types of anemia. Conditions that can cause low folate levels include poor diet, pregnancy, alcoholism, liver disease, certain stomach/intestinal problems, kidney dialysis, among others. Women of childbearing age should receive adequate amounts of Ferograd 525mg/500mg either through their diet or supplements to prevent infant spinal cord birth defects.

How to use Ferograd 525mg/500mg

Take this product by mouth with or without food as directed by your doctor, usually once daily. If you are taking the over-the-counter product, follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.

Dosage is based on your medical condition and response to treatment. Do not increase your dose or take this product more often than directed.

Take this product regularly to get the most benefit from it. To help you remember, take it at the same time each day. Follow the diet plan recommended by your doctor or dietician. See also Notes section.

If your condition persists or worsens, or if you think you may have a serious medical problem, get medical help right away.

Ferograd 525mg/500mg description


A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Ferograd 525mg/500mg is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. [PubChem]

Ferograd 525mg/500mg dosage

Ferograd 525mg/500mg Dosage

Applies to the following strength(s): 1 mg; 0.4 mg; 5 mg/mL; 0.8 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Megaloblastic Anemia

1 mg orally, intramuscularly, subcutaneously or IV once a day. May continue until clinical symptoms of folate deficiency and the hematological profile have normalized.

Usual Adult Dose for Ferograd 525mg/500mg Deficiency

400 to 800 mcg orally, intramuscularly, subcutaneously or IV once a day.

Women of childbearing age, pregnant, and lactating women: 800 mcg orally, intramuscularly, subcutaneously or IV once a day.

Usual Pediatric Dose for Ferograd 525mg/500mg Deficiency


0.1 mg orally, intramuscularly, subcutaneously or IV once a day.


Less than 4 years: up to 0.3 mg orally, intramuscularly, subcutaneously or IV once a day.

4 years or older: 0.4 mg orally, intramuscularly, subcutaneously or IV once a day.

Usual Pediatric Dose for Vitamin/Mineral Supplementation

Recommended daily allowance (RDA):

Premature neonates: 50 mcg/day (15 mcg/kg/day).

Full-term neonates and infants 1 to 6 months: 25 to 35 mcg/day.


1 to 3 years: 150 mcg/day.

4 to 8 years: 200 mcg/day.

9 to 13 years: 300 mcg/day.

14 years and older: 400 mcg/day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Rarely, a dosage of 2 mg/day may be required, particularly in patients with malabsorption, alcoholism, chronic hemolysis, chronic exfoliative skin disease or who are on concomitant anticonvulsant therapy.


Ferograd 525mg/500mg is removed by both hemodialysis and peritoneal dialysis. The amount removed varies with type equipment used.

Because folate may accumulate in patients with end-stage renal disease, side effects may be more likely in this patient who is undergoing dialysis. Once this patient's body stores of folate are replete, three times a week dosing may be just as beneficial as once daily dosing but should portend a lower risk of side effects.

Other Comments

The recommended daily allowance of Ferograd 525mg/500mg for adult males and females ranges from 150 to 200 and 150 to 180 mcg/day, respectively.

There is a potential danger in administering Ferograd 525mg/500mg to patients with undiagnosed anemia, since Ferograd 525mg/500mg may obscure the diagnosis of pernicious anemia by alleviating the hematologic manifestations of the disease while allowing the neurologic complications to progress.

Severe megaloblastic anemia may require therapy for 4 to 5 weeks. Once stabilized, if dietary intake is inadequate, maintenance therapy can be started.

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Ferograd 525mg/500mg interactions

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What other drugs will affect Ferograd 525mg/500mg?


Medications that interfere with your bodys ability to use folate may also increase the need for this vitamin. Medications can interfere with folate utilization, including: anticonvulsant medications (such as phenytoin, and primidone) metformin (sometimes prescribed to control blood sugar in type 2 diabetes) sulfasalazine (used to control inflammation associated with Crohns disease and ulcerative colitis) triamterene (a diuretic) Methotrexate There has been concern about the interaction between vitamin B12 and Ferograd 525mg/500mg. Ferograd 525mg/500mg supplements can correct the anemia associated with vitamin B12 deficiency. Unfortunately, Ferograd 525mg/500mg will not correct changes in the nervous system that result from vitamin B12 deficiency. Permanent nerve damage could theoretically occur if vitamin B12 deficiency is not treated. Therefore, intake of supplemental Ferograd 525mg/500mg should not exceed 1000 micrograms (g, sometimes mcg) per day to prevent Ferograd 525mg/500mg from masking symptoms of vitamin B12 deficiency. It is important for older adults to be aware of the relationship between Ferograd 525mg/500mg and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency. If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains Folic Acid.

Ferograd 525mg/500mg side effects

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What are the possible side effects of Ferograd 525mg/500mg?

Allergic sensitization has been reported following both oral and parenteral administration of Ferograd 525mg/500mg.

Ferograd 525mg/500mg is relatively nontoxic in man. Rare instances of allergic responses to Ferograd 525mg/500mg preparations have been reported and have included erythema, skin rash, itching, general malaise, and respiratory difficulty due to bronchospasm. One patient experienced symptoms suggesting anaphylaxis following injection of the drug. Gastrointestinal side effects, including anorexia, nausea, abdominal distention, flatulence, and a bitter or bad taste, have been reported in patients receiving 15 mg Ferograd 525mg/500mg daily for 1 month. Other side effects reported in patients receiving 15 mg daily include altered sleep patterns, difficulty in concentrating, irritability, overactivity, excitement, mental depression, confusion, and impaired judgment. Decreased vitamin B12 serum levels may occur in patients receiving prolonged Ferograd 525mg/500mg therapy.

In an uncontrolled study, orally administered Ferograd 525mg/500mg was reported to increase the incidence of seizures in some epileptic patients receiving phenobarbital, primidone, or diphenylhydantoin. Another investigator reported decreased diphenylhydantoin serum levels in folate-deficient patients receiving diphenylhydantoin who were treated with 5 mg or 15 mg of Ferograd 525mg/500mg daily.


Ferograd 525mg/500mg contraindications

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What is the most important information I should know about Ferograd 525mg/500mg?

Because it may mask the hematologic abnormalities while neurological damage progresses, Ferograd 525mg/500mg should not be used in the therapy of patients with vitamin B12 deficiency of any cause, unless there is associated folate deficiency. The Ferograd 525mg/500mg content of one tablet a day however, is unlikely to mask pernicious anemia should this condition be present. Also, pregnancy during pernicious anemia is very rare.

Active ingredient matches for Ferograd 525mg/500mg:

Folic Acid in Luxembourg.

List of Ferograd 525mg/500mg substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Ferose DPS 50mg x 1mL DPS / 15ml$ 0.57
50 mg x 1 mL x 15ml$ 0.57
Ferose SYR Elemental iron 15 mg, folicacid 0.25 mg, vitamin B12 3.75mcg, Elemental zinc 5.5 mg/5mL. SYR / 150ml (Adcock Ingram)$ 1.17
150ml (Adcock Ingram)$ 1.17
FEROSE SYR syr 150ml (Adcock Ingram)$ 1.31
Ferose TAB Zinc picolinate 52 mg, Folicacid 0.5 mg, Vitamin B12 7.5mcg. TAB / 10$ 0.67
10's$ 0.67
Dragee; Oral; Folic Acid 0.8 mg; Iron / Ferrous Polymaltose 100 mg (Altana)
100's (Medicamen Biotech Ltd.)$ 7.43
Ferro 200 ml Syrup (Medicamen Biotech Ltd.)$ 0.06
Ferro 150 ml Syrup (Medicamen Biotech Ltd.)$ 0.03
Ferro 100+0.35 Tablet (Medicamen Biotech Ltd.)$ 0.07
FERRO tab 10's (Medicamen Biotech Ltd.)$ 0.74
10's (Khandelwal Laboratories Pvt Ltd.)$ 0.36
Ferrum Fol 100+0.35 Tablet (Khandelwal Laboratories Pvt Ltd.)$ 0.04
FERRUM FOL tab 10's (Khandelwal Laboratories Pvt Ltd.)$ 0.36
10's (Pharmed Limited)$ 0.71
Ferst 150 ml Syrup (Pharmed Limited)$ 0.03
Ferst 15 ml Drop (Pharmed Limited)$ 0.03
Ferst 100 mg+750 mcg Capsule (Pharmed Limited)$ 0.07
FERST cap 10's (Pharmed Limited)$ 0.71
Tablet; Oral; Folic Acid 0.4 mg (Lifepharma)
Fetanium tab 5 mg 60's (Akums Drug)
Fexid SUSP Carbonyl iron 30 mg, Folicacid 1 mg, Cyanocobalamin 6mcg, Zinc 11 mg. SUSP / 100ml (Overseas)$ 0.72
Fexid SUSP Carbonyl iron 30 mg, Folicacid 1 mg, Cyanocobalamin 6mcg, Zinc 11 mg. SUSP / 200ml (Overseas)$ 1.35
100ml (Overseas)$ 0.72
200ml (Overseas)$ 1.35


  1. DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN 5'-PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "folic acid". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "folic acid". http://www.drugbank.ca/drugs/DB00158 (accessed September 17, 2018).


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