Fesafe Uses

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What is Fesafe?

Carbonyl Fesafe is an Fesafe replacement product. You normally get Fesafe from the foods you eat. Fesafe helps your body produce red blood cells that carry oxygen through your blood to tissues and organs.

Carbonyl Fesafe is used to treat or prevent Fesafe deficiency and Fesafe deficiency anemia.

Carbonyl Fesafe may also be used for purposes not listed in this medication guide.

Fesafe indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Film-Coated Tablet: Treatment of Fesafe deficiency. Prevention of Fesafe deficiency during pregnancy.

Syrup: All cases of Fesafe deficiency and Fesafe deficiency anaemia.

Drops: General: Hypochromic or masked Fesafe deficiency anaemias. General weakness. Convalescence. Blood losses. Tropical microcytic anaemia. Anaemias due to infections. For maintenance therapy in pernicious anaemia. As an adjuvant in treating chronically ill or undernourished patients.

Women: Fesafe deficiency due to menstruation. During and after pregnancy and lactation. Menorrhagia.

Children: All types of hypochromic anaemias and masked Fesafe deficiencies. Inappetence. Retarded growth. Weakness. Unsound dietary habits. To speed up restoration of depleted Fesafe reserves.

How should I use Fesafe?

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Use Fesafe suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Fesafe suspension.

Fesafe description

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Each 5 mL syrup contains: Diastase (1:50) 135 mg, pepsin 50 mg, papain BPC 50 mg, vitamin B1 5 mg, vitamin B2 2 mg, vitamin B6 2 mg, vitamin B12 5 mcg, calcium pantothenate 1 mg and nicotinamide 20 mg.

Fesafe is a pleasantly flavoured syrup, containing digestive enzymes and vitamins of the B-complex group. Abdominal cramps, flatulence, heartburn and nausea can occur as a result of indigestion. Fesafe is the ideal cure to facilitate digestion and to strengthen the GIT.

Fesafe's balanced formulation provides an ideal supplementation that meets the demands and replenishes vitamins stores in the body.

Fesafe dosage

Film-Coated Tablet: Treatment of Fesafe Deficiency with Reduced Number of Red Blood Cells in Adults and Children over 12 Years: 1 to 3 tablets once daily or divided into separate doses for about 3 to 5 months.

After normalisation of the red blood pigment (haemoglobin) value, continue with 1 tablet once daily for several weeks. This will replenish the Fesafe stores.

Treatment of Fesafe Deficiency with Reduced Number of Red Blood Cells in Pregnancy: 2 to 3 tablets once daily or divided into separate doses.

After normalisation of the red blood pigment value, continue with 1 tablet once daily until, at least, the end of pregnancy. This will replenish the Fesafe stores and provide the increased amount of Fesafe required during pregnancy.

Treatment of Fesafe Deficiency with Normal Number of Red Blood Cells in Adults, Pregnancy, and Children over 12 years, and Prevention of Fesafe Deficiency in Pregnancy: 1 tablet once daily for 1 to 2 months.

Syrup: Adults: 5 mL 2 to 3 times daily before meals.

Children: 5 mL 1 to 2 times daily before meals.

Infants: Begin with 2.5 mL daily and gradually increase to 5 mL daily.

Drops: Adults: 20 drops 2 to 3 times daily during or after a meal.

Children: 20 drops 1 to 2 times daily during or after a meal.

Infants: Begin with 6 drops daily and gradually increase to 20 drops daily.

Fesafe may be mixed with fruit, vegetable juices or other liquids if desired.

Best results are obtained by adequate dosage and regular administration. It is recommended that the therapy in conformity to the degree of Fesafe deficiency should be continued for at least 1 to 2 months.

Administration: Take Fesafe during or immediately after meal.

Duration of use depends upon the degree of Fesafe deficiency.

Do not discontinue sooner than recommended as this may reduce the success of therapy.

Fesafe interactions

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What other drugs will affect Fesafe?

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Drug interactions were not noted and were not studied in clinical studies.

Feridex I.V. (ferumoxides injectable solution) administration provides elemental Fesafe. In patients who are receiving supplemental Fesafe orally or parenterally, the dose of supplemental Fesafe may need to be decreased.

The effect of concomitant parenteral Fesafe on Feridex I.V. dosing is not known.

Laboratory Test Findings

Serum Fesafe levels may be above the normal range following Feridex I.V. (ferumoxides injectable solution) administration. Transient increases in serum Fesafe of 15–100% of baseline were observed 18 to 24 hours after Feridex I.V. (ferumoxides injectable solution) administration, and returned to normal in most patients by 7 days after administration. Increases in serum ferritin levels were seen 1 to 7 days after administration.

In a Phase 1 study in normal subjects, PTT was statistically significantly increased; however, all values were within the normal range and no subjects had a more than 40% increase from baseline. In clinical trials of patients who had baseline hematologic abnormalities associated with underlying liver disease, an effect of Feridex I.V. (ferumoxides injectable solution) on platelet or PTT was not demonstrated. In patients with low hematocrit and hemoglobin, over a period of 48 hours to 7 days after Feridex I.V. (ferumoxides injectable solution), the serum Fesafe, the hematocrit and hemoglobin levels increase slightly.

Fesafe side effects

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What are the possible side effects of Fesafe?

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Applies to carbonyl Fesafe: suspension

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; darkened or green stools; diarrhea; loss of appetite; nausea; stomach cramps, pain, or upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking carbonyl Fesafe (the active ingredient contained in Fesafe)

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or tarry stools; blood or streaks of blood in the stool; fever; severe or persistent nausea, stomach pain, or vomiting; vomit that looks like blood or coffee grounds.

Fesafe contraindications

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What is the most important information I should know about Fesafe?

All cases of Fesafe overload and disturbances in utilization of Fesafe.

Film-Coated Tablet: Allergy to Fesafe (III)-hydroxide polymaltose complex or any of the other ingredients of Fesafe.

An Fesafe overload in the body.

Disturbed use of Fesafe by the body.

Reduced number of red blood cells (anaemia), not caused by Fesafe deficiency, such as due to increased red blood cell breakdown, vitamin B12 deficiency.



Active ingredient matches for Fesafe:

Iron in India.

Elemental iron in India.


Unit description / dosage (Manufacturer)Price, USD
100 mg x 10's$ 0.69
Fesafe 100 ml Syrup$ 0.04
Fesafe 100 mg Tablet$ 0.07
FESAFE tab 100 mg x 10's (RND Lab)$ 0.69

List of Fesafe substitutes (brand and generic names):

Solution; Oral; Iron / Iron III Hydroxide Polymaltose Complex 50 mg / 5 ml
50 mg x 5 mL x 100ml (RND Lab)$ 0.87
50 mg x 5 mL x 300ml (RND Lab)$ 1.68
FESAFE SYR syr 50 mg x 5 mL x 100ml (RND Lab)$ 0.91
FESAFE SYR syr 50 mg x 5 mL x 300ml (RND Lab)$ 1.77
Fetol Z Plus 50+22.5+0.5 Capsule (Talwar Pharma)$ 0.06
Fetose 15 ml Drop (Biostrass Health Sciences)$ 0.04
Fetose 200 ml Suspension (Biostrass Health Sciences)$ 0.02
Fetose Capsule (Biostrass Health Sciences)$ 0.17
Fexid Carbonyl iron 100 mg, Folicacid 1.5 mg, Vitamin B12 15mcg. CAP / 10 (Overseas Health Care Pvt. Ltd.)$ 0.87
10's (Overseas Health Care Pvt. Ltd.)$ 0.87
Fexid 100 mg+1.5 mg+15 mcg Capsule (Overseas Health Care Pvt. Ltd.)$ 0.09
Fexid 200 ml Suspension (Overseas Health Care Pvt. Ltd.)$ 0.03
Fexid 100 ml Suspension (Overseas Health Care Pvt. Ltd.)$ 0.04
FEXID cap 10's (Overseas Health Care Pvt. Ltd.)$ 0.87
Fezest Capsule (Alcare Laboratories Pvt Ltd)$ 0.08
FIPP1O-XT INJ inj 20 mg x 2.5ml (Aden Healthcare)$ 0.49
FITRAX INJ inj 20 mg x 2.5ml (Pax Healthcare)$ 0.49
Foferyz Inj Injection (Aero-Chem Neutron Pvt Ltd)$ 0.60
FOFERYZ tab 15's (Aero-Chem Neutron Pvt Ltd)
FOFERYZ INJ inj 20 mg x 2.5ml (Aero-Chem)
FOFERYZ INJ inj 20 mg x 5ml (Aero-Chem)
Fol V 5 mg Tablet (Burnet Pharmaceuticals Pvt. Ltd.)$ 0.02
Folbee HT 200 ml Syrup (Trojan Pharma Ltd)$ 0.03
50 mg x 5 mL x 150ml (Alembic)$ 0.87
FOLINAL PLUS SYR syr 50 mg x 5 mL x 150ml (Alembic)$ 0.87
GEFER FORTE inj 20 mg x 1 mL x 5ml (Strides)$ 4.44
GEFER INJ inj 20 mg x 1 mL x 2.5ml (Strides)$ 2.27
Drops; Oral; Iron / Potassium-Iron / III Citrate-Phosphate Complex
Capsule; Oral; Iron / Ferrous HVP Chelate 25 mg
Glohar III 150 ml Syrup (Taurus Laboratories Pvt. Ltd.)$ 0.03
Glohar III 100+550 Capsule (Taurus Laboratories Pvt. Ltd.)$ 0.07
Glorin Capsule (Medoz Pharmaceuticals)$ 0.03
Drops; Oral; Iron / Ferrous Gluconate 23 mg / ml (Knop)
Syrup; Oral; Iron / Ferrous Gluconate 7 mg / ml (Knop)
Tablet, Extended Release; Oral; Iron / Ferrous Fumarate 18 mg

References

  1. PubChem. "Iron". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Iron". http://www.drugbank.ca/drugs/DB01592 (accessed September 17, 2018).
  3. MeSH. "Trace Elements". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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