Consists of frangula bark, Linseed, malt extract, rhubarb, senna
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Frangula bark/Linseed/malt extract/rhubarb/senna Uses |
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Consists of frangula bark, Linseed, malt extract, rhubarb, senna
Brief Treatment of occasional constipation.
Combinations requiring precautions: digitalis, other potassium levels [diuretics potassium levels (alone or in combination), amphotericin B (IV), corticosteroids (systemically), tetracosactide].
Possibility of diarrhea, abdominal pain especially in patients suffering from irritable bowel syndrome.
- Possibility of hypokalemia.
- Sometimes, discoloration of urine without clinical significance.
This medication is not recommended in the following situations:
- Organic colopathies inflammatory (ulcerative colitis, Crohn’s disease...),
- Bowel obstruction or subocclusif,
- Abdominal pain syndrome of unknown cause,
- State of severe dehydration with electrolyte depletion,
- Children under 10 years.
gastrointestinal disorders
Constipation.
difficulty in breathing, intestinal blockage, skin rash, itching, swallowing difficulty - feeling of lump in throat
Do not take if you have an intestinal blockage or impacted stool.
Short-term treatment of constipation; preoperative and preradiographic bowel evacuation for procedures involving GI tract.
None well documented.
Gastrointestinal Disorders
A transient local burning sensation at the site of application occurs very commonly >1/10).
Temporary discolouration of teeth or oral mucosa have been described commonly >1/100, <1/10) following administration of this medicine.
Nausea, vomiting, or other symptoms of appendicitis; acute surgical abdomen; fecal impaction; intestinal obstruction; undiagnosed abdominal pain.
Senna is also known as Cassia, Fan Xie Ye, Alejandrina, Séné, Sennae, and Tinnevelly.
Senna is likely effective in alternative medicine as an aid in treating occasional constipation in adults and children at least 2 years old. Senna is sometimes used together with another laxative or stool softener such as lactulose, psyllium, docusate, or mineral oil.
Senna is possibly effective as a bowel preparation before colonoscopy.
Other uses not proven with research include weight loss, irritable bowel syndrome, hemorrhoids, anal fissures (tears in the lining of the anus), or after anal or rectal surgery.
It is not certain whether senna is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Senna should not be used in place of medication prescribed for you by your doctor.
Senna is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Senna may also be used for purposes not listed in this product guide.
Laxative especially in cases requiring the maintenance
of a soft stool to avoid straining (e.g. When there has
been hernia, aneurysm, hypertension, myocardial
infarction, or cerebrovascular accident, or after a
haemorrhoidectomy or abdominal surgery).
It is also used as an emollient and moisturizer to prevent
or relieve the signs and symptoms of dry skin.
Use Senna as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Senna.
Constipation: Relieves occasional constipation (irregularity); generally causes bowel movement in 6 to 12 hours
Data from one uncontrolled study evaluating the use of senna as an adjunct to reduce the amount of polyethylene glycol (PEG) solution necessary suggests that the use of senna as an adjunct in this setting may be beneficial. Additional data may be necessary to further define the role of senna as an adjunct in colonic cleansing before colonoscopy.
Based on the recommendations for Optimizing Adequacy of Bowel Cleansing for Colonoscopy, the US Multi-Society Task Force on Colorectal Cancer by the American College of Gastroenterology, American Gastroenterological Association, and the American Society for Gastrointestinal Endoscopy, the use of adjunctive agents for precolonoscopy cleansing of the mucosa such as simethicone, flavored electrolyte solutions (eg, Gatorade), prokinetics, spasmolytics, bisacodyl, senna, olive oil, and probiotics is not recommended for routine use since none have consistently shown improved efficacy, safety, or tolerability of the bowel preparation. However, senna may be used in select situations.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Leaves,
Generic: (454 g)
Liquid,
Senexon: 8.8 mg/5 mL (237 mL [DSC]) [contains methylparaben, propylene glycol, propylparaben]
Generic: 8.8 mg/5 mL (237 mL)
Syrup,
Senna-GRX: 8.8 mg/5 mL (15 mL, 236 mL) [contains parabens, propylene glycol]
Generic: 8.8 mg/5 mL (5 mL, 236 mL, 237 mL); 176 mg/5 mL (15 mL, 237 mL)
Tablet,
Ex-Lax: 15 mg [DSC] [sodium free]
Ex-Lax Maximum Strength: 25 mg [DSC] [sodium free]
Senna: 8.6 mg
GoodSense Laxative Pills: 25 mg [contains brilliant blue fcf (fd&c blue #1), corn starch]
GoodSense Senna Laxative: 8.6 mg
Perdiem Overnight Relief: 15 mg [DSC]
Senexon: 8.6 mg [DSC]
Senna Lax: 8.6 mg [DSC]
Senna Laxative: 8.6 mg
Senna Smooth: 15 mg [contains sodium benzoate]
Senna-Lax: 8.6 mg
Senna-Tabs: 8.6 mg
Senna-Time: 8.6 mg
SennaCon: 8.6 mg [DSC]
Senno: 8.6 mg
Senna: 8.6 mg
Senna Extra Strength: 17.2 mg
Senna XTRA: 17.2 mg [DSC]
Generic: 8.6 mg
Tablet Chewable,
Ex-Lax: 15 mg [DSC]
Ex-Lax: 15 mg [DSC] [chocolate flavor]
Note: Several types of senna products are available on the market and multiple formulations exist that are not equivalent; products composed of sennosides are considered OTC medications; senna pod concentrate and senna leaf extract are considered dietary supplements and are not interchangeable on a mL-to-mL (or mg-to-mg) basis with other senna products that contain sennosides; close attention must be paid to the product description and concentration when ordering or administering.
Constipation:
Sennosides:
Syrup (8.8 mg sennosides/5 mL): 10 to 15 mL (17.6 mg to 26.4 mg sennosides) once daily; maximum: 15 mL (26.4 mg sennosides) twice daily.
Tablets:
8.6 mg sennosides/tablet: Two tablets (17.2 mg sennosides) once daily; maximum: 4 tablets (34.4 mg sennosides) twice daily
15 mg sennosides/tablet: Two tablets (30 mg sennosides) once or twice daily
17.2 mg sennosides/tablet: One tablet (17.2 mg sennosides) once daily; maximum: 2 tablets (34.4 mg sennosides) twice daily
25 mg sennosides/tablet: Two tablets (50 mg sennosides) once or twice daily
Senna leaf extract syrup (176 mg/5 mL senna leaf extract): Note: Senna leaf extract is considered a dietary supplement and is not interchangeable on a mL-to-mL (or mg-to-mg) basis with other senna products that contain sennosides.
10 to 15 mL (352 to 528 mg senna leaf extract) once daily (preferably at bedtime); may increase to 10 to 15 mL (352 to 528 mg senna leaf extract) twice daily if needed; maximum daily dose: 30 mL/day
Refer to adult dosing.
Note: Several types of senna products are available on the market and multiple formulations exist that are not equivalent; products composed of sennosides are considered OTC medications; senna pod concentrate and senna leaf extract are considered dietary supplements and are not interchangeable on a mL to mL (or mg to mg) basis with other senna products that contain sennosides; close attention must be paid to the product description and concentration when ordering or administering.
Constipation:
Sennosides:
Syrup (8.8 mg sennosides/5 mL):
Children 2 to <6 years: 2.5 to 3.75 mL (4.4 to 6.6 mg sennosides) at bedtime, not to exceed 3.75 mL (6.6 mg sennosides) twice daily
Children 6 to <12 years: 5 to 7.5 mL (8.8 to 13.2 mg sennosides) at bedtime, not to exceed 7.5 mL (13.2 mg sennosides) twice daily
Children ≥12 years and Adolescents: 10 to 15 mL (17.6 mg to 26.4 mg sennosides) at bedtime, not to exceed 15 mL (26.4 mg sennosides) twice daily.
Tablets:
8.6 mg sennosides/tablet:
Children 2 to <6 years: / tablet (4.3 mg sennosides) at bedtime, not to exceed 1 tablet (8.6 mg sennosides) twice daily
Children 6 to <12 years: 1 tablet (8.6 mg sennosides) at bedtime, not to exceed 2 tablets (17.2 mg sennosides) twice daily
Children ≥12 years and Adolescents: 2 tablets (17.2 mg sennosides) at bedtime, not to exceed 4 tablets (34.4 mg sennosides) twice daily
15 mg sennosides/tablet:
Children 6 to <12 years: 1 tablet (15 mg sennosides) once or twice daily
Children ≥12 years and Adolescents: 2 tablets (30 mg sennosides) once or twice daily
25 mg sennosides/tablet:
Children 6 to <12 years: 1 tablet (25 mg sennosides) once or twice daily
Children ≥12 years and Adolescents: 2 tablets (50 mg sennosides) once or twice daily
Senna pod concentrate liquid (Fletcher's Laxative for Kids; 167 mg/5 mL senna pod concentrate): Note: Senna pod concentrate is considered a dietary supplement and is not interchangeable on a mL to mL (or mg to mg) basis with other senna products that contain sennosides.
Children 2 to <6 years: 5 to 10 mL (167 to 333 mg senna pod concentrate) once or twice daily
Children and Adolescents 6 to 15 years: 10 to 15 mL (333 to 500 mg senna pod concentrate) once or twice daily
Senna Leaf Extract Syrup (176 mg/5 mL senna leaf extract): Note: Senna leaf extract is considered a dietary supplement and is not interchangeable on a mL to mL (or mg to mg) basis with other senna products that contain sennosides. Begin with once daily dosing (at bedtime); increase to twice daily if needed.
Children 2 to <6 years: 2.5 to 3.75 mL (88 to 132 mg senna leaf extract) once or twice daily; maximum daily dose: 7.5 mL/day
Children ≥6 years to <12 years: 5 to 7.5 mL (176 to 264 mg senna leaf extract) once or twice daily; maximum daily dose: 15 mL/day
Children ≥12 years and Adolescents: 10 to 15 mL (352 to 528 mg senna leaf extract) once or twice daily; maximum daily dose: 30 mL/day
Bowel evacuation: Children ≥12 years and Adolescents:
Oral: 130 mg sennosides between 2:00 PM to 4:00 PM on the day prior to procedure
See also:
What other drugs will affect Senna?
Dichlorphenamide: Laxatives may enhance the hypokalemic effect of Dichlorphenamide. Monitor therapy
Polyethylene Glycol-Electrolyte Solution: Senna may enhance the adverse/toxic effect of Polyethylene Glycol-Electrolyte Solution. Monitor therapy
See also:
What are the possible side effects of Senna?
Applies to senna: oral capsule liquid filled, oral flake, oral granule, oral liquid, oral powder for suspension, oral suspension, oral syrup, oral tablet
In addition to its needed effects, some unwanted effects may be caused by senna (the active ingredient contained in Senna). In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking senna:
Incidence not known:
See also:
What is the most important information I should know about Senna?
You should not use this medication if you are allergic to bisacodyl, or if you have:
severe stomach pain, nausea, or vomiting;
a perforated bowel;
a blockage in your intestines;
fructose or galactose intolerance;
an allergy to yellow food dye;
severe constipation or dehydration;
inflammatory bowel disease, toxic megacolon; or
a sudden change in bowel habits lasting 2 weeks or longer.
People with eating disorders (such as anorexia or bulimia) should not use this medication without the advice of a doctor.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely use bisacodyl:
kidney disease;
trouble swallowing;
a history of bowel obstruction, diverticulitis, ulcerative colitis, or other intestinal disorder; or
if you are taking a diuretic ("water pill").
Frangula bark/Linseed/malt extract/rhubarb/senna
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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