Franirose Uses

Is this medication very expensive?
sponsored

What is Franirose?

Franirose is a type of sugar. It is broken down in the large intestine into mild acids that draw water into the colon, which helps soften the stools.

Franirose is used to treat chronic constipation.

Franirose is sometimes used to treat or prevent certain conditions of the brain that are caused by liver failure, which can lead to confusion, problems with memory or thinking, behavior changes, tremors, feeling irritable, sleep problems, loss of coordination, and loss of consciousness.

Franirose may also be used for purposes not listed in this medication guide.

Franirose indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
sponsored

For the prevention and treatment of portal-systemic encephalopathy, including the stages of hepatic pre-coma and coma.

Controlled studies have shown that Franirose therapy reduces the blood ammonia levels by 25–50%; this is generally paralleled by an improvement in the patients' mental state and by an improvement in EEG patterns. The clinical response has been observed in about 75% of patients, which is at least as satisfactory as that resulting from neomycin therapy. An increase in patients' protein tolerance is also frequently observed with Franirose solution therapy. In the treatment of chronic portal-systemic encephalopathy, Franirose solution has been given for over 2 years in controlled studies.

How should I use Franirose?

Use Franirose crystals as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Franirose crystals.

Uses of Franirose in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
sponsored

This medication is a laxative used to treat constipation. It may help to increase the number of bowel movements per day and the number of days you have a bowel movement. Franirose is a colonic acidifier that works by increasing stool water content and softening the stool. It is a man-made sugar solution.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug, but may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if has been so prescribed by your health care professional.

This drug is also used to treat or prevent complications of liver disease (hepatic encephalopathy).

How to use Franirose

Take this medication by mouth, usually once daily for constipation, or as directed by your doctor. If you are taking the solution, to improve the taste, you may mix it into fruit juice, water, milk, or a soft dessert. If you are using the crystals in packets, dissolve the contents of the packet in half a glass of water (4 ounces or 120 milliliters), or as directed by your doctor.

Use this medication regularly in order to get the most benefit from it. Remember to take it at the same time each day. Dosage is based on your medical condition and response to therapy.

It may take up to 48 hours to have a bowel movement. Inform your doctor if your condition persists or worsens.

Franirose description

sponsored

Franirose syrup, which contains Lactulose with other sugars eg, galactose and lactose, is used in the treatment of constipation and hepatic encephalopathy. Franirose is a disaccharide, a sugar molecule composed of 2 smaller sugar molecules bonded together, in this case, fructose and galactose. Franirose is a solid substance that is very soluble in water and has a sweet taste. It is sweeter than lactose but not as sweet as fructose. Chemically, Franirose is also known as 4-O-β-D-galactopyranosyl-D-fructofuranose. The molecular formula is C12H22O11 with a molecular weight of 342.3 daltons.

Franirose dosage

Franirose Dosage

Generic name: Franirose 10g in 15mL

Dosage form: oral solution

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Oral

Adult

The usual adult oral dosage is 30 to 45 mL (2 to 3 tablespoonfuls, containing 20 g to 30 g of Franirose Solution) three or four times daily. The dosage may be adjusted every day or two to produce 2 or 3 soft stools daily.

Hourly doses of 30 to 45 mL of Franirose Solution may be used to induce the rapid laxation indicated in the initial phase of the therapy of portal-systemic encephalopathy. When the laxative effect has been achieved, the dose of Franirose Solution may then be reduced to the recommended daily dose. Improvement in the patient's condition may occur within 24 hours but may not begin before 48 hours or even later.

Continuous long-term therapy is indicated to lessen the severity and prevent the recurrence of portal-systemic encephalopathy. The dose of Franirose Solution for this purpose is the same as the recommended daily dose.

Pediatric

Very little information on the use of Franirose in pediatric patients has been recorded. As with adults, the subjective goal in proper treatment is to produce 2 to 3 soft stools daily. On the basis of information available, the recommended initial daily oral dose in infants is 2.5 to 10 mL in divided doses. For older pediatric patients, the total daily dose is 40 to 90 mL. If the initial dose causes diarrhea, the dose should be reduced immediately. If diarrhea persists, Franirose Solution should be discontinued.

Rectal

When the adult patient is in the impending coma or coma stage of portal-systemic encephalopathy and the danger of aspiration exists, or when the necessary endoscopic or intubation procedures physically interfere with the administration of the recommended oral doses, Franirose Solution may be given as a retention enema via a rectal balloon catheter. Cleansing enemas containing soapsuds or other alkaline agents should not be used.

Three hundred mL of Franirose Solution should be mixed with 700 mL of water or physiologic saline and retained for 30 to 60 minutes. Franirose Solution enema may be repeated every 4 to 6 hours. If the enema is inadvertently evacuated too promptly, it may be repeated immediately.

The goal of treatment is reversal of the coma stage in order that the patient may be able to take oral medication. Reversal of coma may take place within 2 hours of the first enema in some patients. Franirose Solution, given orally in the recommended doses, should be started before Franirose Solution by enema is stopped entirely.

More about Franirose (Franirose)

Consumer resources

Professional resources

Related treatment guides

Franirose interactions

See also:
What other drugs will affect Franirose?

sponsored

No laxative should be taken within 2 hrs of another medication because the desired effect of the other medication may be reduced.

Antacids: Antacids given concurrently with Franirose may inhibit the desired Franirose-induced drop in colonic pH. Therefore, a possible lack of desired effect of treatment should be taken into consideration before such drugs are given concomitantly with Franirose.

Neomycin: In some situations, neomycin administered together with Franirose is more effective than either one alone.

Although, theoretically, the elimination of certain colonic bacteria by neomycin and possibly other anti-infective agents may interfere with the desired degradation of Franirose and thus prevent the acidification of colonic contents. There have been some reports that Franirose-fermenting bacteria are relatively resistant to neomycin, which may explain why a combination could work in some cases. The status of the Franirose-treated patients should be closely monitored in the event of concomitant oral antibiotic therapy.

Franirose side effects

See also:
What are the possible side effects of Franirose?

Summary of the Safety Profile: Flatulence may occur during the 1st few days of treatment. As a rule, it disappears after a few days. When dosages higher than instructed are used, abdominal pain and diarrhea may occur. In such cases, the dosage should be decreased.

If high doses (normally only associated with, hepatic encephalopathy or portal systemic encephalopathy) are used for an extended period of time, the patient may experience an electrolyte imbalance due to diarrhea.

List of Adverse Reactions: The following undesirable effects have been experienced with the following indicated frequencies in Franirose-treated patients in placebo-controlled clinical trials: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1000 to <1/100); rare (≥1/10,000 to <1/1000); very rare (<1/10,000). Gastrointestinal Disorders: Very Common: Diarrhea. Common: Flatulence, abdominal pain, nausea, vomiting.

Investigations: Uncommon: Electrolyte imbalance due to diarrhea.

Paediatric Population: The safety profile in children is expected to be similar as in adults.

Franirose contraindications

See also:
What is the most important information I should know about Franirose?

Since KRISTALOSEā„¢ (D-Franirose) for

Oral Solution contains galactose (less than 0.3 g/10 g as a total sum with lactose), it is contraindicated in patients who require a low galactose diet.

Active ingredient matches for Franirose:

Lactulose in Estonia, Lithuania.


List of Franirose substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD
Freshcol 100 ml Syrup (HRD Supra Healthcare)$ 0.19
Freshcol 200 ml Syrup (HRD Supra Healthcare)$ 0.18
100ml (Aamorb (St. Morison))$ 1.11
200ml (Aamorb (St. Morison))$ 2.06
Fresky - SOLN / 100ml (Aamorb (St. Morison))$ 1.11
Fresky - SOLN / 200ml (Aamorb (St. Morison))$ 2.06
FRESKY SOLUTION 1 bottle / 100 ML solution each (Aamorb (St. Morison))$ 1.55
FRESKY SOLUTION 1 bottle / 200 ML solution each (Aamorb (St. Morison))$ 2.53
FRESKY oral soln 100ml (Aamorb (St. Morison))$ 1.70
FRESKY oral soln 200ml (Aamorb (St. Morison))$ 2.53
Fresky - SOLN / 100ml (Aamorb (St. Morison))$ 1.11
Fresky - SOLN / 200ml (Aamorb (St. Morison))$ 2.06
Fresky NA Solution (Aamorb (St. Morison))$ 2.53
Syrup; Oral; Lactulose 670 mg / ml (Melisana)
Liquid; Oral; Lactulose 667 mg / ml (Genpharm)
Solution; Oral, Rectal; Lactulose 10 g / 15 ml
Generlac solution 10 g/15mL (Morton Grove Pharmaceuticals, Inc. (US))
GENTALOSE SYRUP 1 bottle / 100 ML syrup each (Biocon)$ 1.25
GENTALOSE SYRUP 1 bottle / 200 ML syrup each (Biocon)$ 2.41
GENTALOSE SYRUP 1 bottle / 500 ML syrup each (Biocon)$ 5.54
GENTALOSE oral liqd 10 g x 15 mL x 100ml (Biocon)$ 1.25
GENTALOSE oral liqd 10 g x 15 mL x 200ml (Biocon)$ 2.41
GENTALOSE oral liqd 10 g x 15 mL x 500ml (Biocon)$ 5.54
Syrup; Oral; Lactulose 0.67 g / ml (Gerard)
GEROLAC 10 GM SYRUP 1 bottle / 100 ML syrup each (Orchid Chemicals & Pharmaceuticals Ltd)$ 1.30
Gerolac 10gm Syrup (Orchid Chemicals & Pharmaceuticals Ltd)$ 1.30
Syrup; Oral; Lactulose 667 mg / ml
GUSH Liquid / 10gm per 15ml / 140ml units (Panacea Biotec Ltd)$ 1.25
Gush 10g/15mL SYR / 140ml (Panacea Biotec Ltd)$ 1.25
10 g x 15 mL x 140ml (Panacea Biotec Ltd)$ 1.25
Gush 140 ml Syrup (Panacea Biotec Ltd)$ 0.13
GUSH 10 GM/3.5 GM POWDER 1 box / 90 GM powder each (Panacea Biotec Ltd)$ 3.48

References

  1. DailyMed. "LACTULOSE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "lactulose". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "lactulose". http://www.drugbank.ca/drugs/DB00581 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Franirose are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Franirose. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


Consumer reported time for results

No survey data has been collected yet


Consumer reported age

No survey data has been collected yet


Consumer reviews


There are no reviews yet. Be the first to write one!


Your name: 
Email: 
Spam protection:  < Type 28 here

Information checked by Dr. Sachin Kumar, MD Pharmacology

| Privacy Policy
This site does not supply any medicines. It contains prices for information purposes only.
© 2003 - 2024 ndrugs.com All Rights Reserved