What is Frusemide-Hameln?
Frusemide-Hameln belongs to a group of medicines called loop diuretics (also known as water pills). Frusemide-Hameln is given to help treat fluid retention (edema) and swelling that is caused by congestive heart failure, liver disease, kidney disease, or other medical conditions. It works by acting on the kidneys to increase the flow of urine.
Frusemide-Hameln is also used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Frusemide-Hameln is available only with your doctor's prescription.
Frusemide-Hameln indications
Parenteral therapy should be reserved for patients unable to take oral medication or for patients in emergency clinical situations.
Edema: Frusemide-Hameln is indicated in adults and pediatric patients for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Frusemide-Hameln is particularly useful when an agent with greater diuretic potential is desired.
Frusemide-Hameln is indicated as adjunctive therapy in acute pulmonary edema. The intravenous administration of Frusemide-Hameln is indicated when a rapid onset of diuresis is desired, e.g., in acute pulmonary edema.
If gastrointestinal absorption is impaired or oral medication is not practical for any reason, Frusemide-Hameln is indicated by the intravenous or intramuscular route.
Parenteral use should be replaced with oral Frusemide-Hameln as soon as practical.
How should I use Frusemide-Hameln?
Use Frusemide-Hameln solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Frusemide-Hameln solution by mouth with or without food.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- If you take cholestyramine, colestipol, or sucralfate, ask your doctor or pharmacist how to take them with Frusemide-Hameln solution.
- Frusemide-Hameln solution may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
- If you miss a dose of Frusemide-Hameln solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Frusemide-Hameln solution.
Uses of Frusemide-Hameln in details
Frusemide-Hameln is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen.
This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Frusemide-Hameln is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This medication may also be used to decrease a high level of calcium in the blood (hypercalcemia).
How to use Frusemide-Hameln
Read the Patient Information Leaflet if available from your pharmacist before you start taking Frusemide-Hameln and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth as directed by your doctor, with or without food, usually once or twice daily. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.
Dosage is based on your medical condition, age, and response to treatment. For children, the dose is also based on weight. Older adults usually start with a lower dose to decrease the risk of side effects. Do not increase your dose or take it more often than directed.
Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) of the day as directed. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
Sucralfate, cholestyramine, and colestipol can decrease the absorption of Frusemide-Hameln. If you are taking any of these drugs, separate the timing of each dose from Frusemide-Hameln by at least 2 hours.
Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase).
Frusemide-Hameln description
A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections. Frusemide-Hameln has also been administered orally in the treatment of trypanosomiasis.
Frusemide-Hameln dosage
Frusemide-Hameln Dosage
Generic name: Frusemide-Hameln 20mg
Dosage form: tablet
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Edema
Therapy should be individualized according to patient response to gain maximal therapeutic response and to determine the minimal dose needed to maintain that response.
Adults -- The usual initial dose of Frusemide-Hameln is 20 to 80 mg given as a single dose. Ordinarily a prompt diuresis ensues. If needed, the same dose can be administered 6 to 8 hours later or the dose may be increased. The dose may be raised by 20 or 40 mg and given not sooner than 6 to 8 hours after the previous dose until the desired diuretic effect has been obtained. The individually determined single dose should then be given once or twice daily (eg, at 8 am and 2 pm). The dose of Frusemide-Hameln may be carefully titrated up to 600 mg/day in patients with clinically severe edematous states.
Edema may be most efficiently and safely mobilized by giving Frusemide-Hameln on 2 to 4 consecutive days each week.
When doses exceeding 80 mg/day are given for prolonged periods, careful clinical observation and laboratory monitoring are particularly advisable.
Geriatric patients -- In general, dose selection for the elderly patient should be cautious, usually starting at the low end of the dosing range.
Pediatric patients -- The usual initial dose of oral Frusemide-Hameln in pediatric patients is 2 mg/kg body weight, given as a single dose. If the diuretic response is not satisfactory after the initial dose, dosage may be increased by 1 or 2 mg/kg no sooner than 6 to 8 hours after the previous dose. Doses greater than 6 mg/kg body weight are not recommended. For maintenance therapy in pediatric patients, the dose should be adjusted to the minimum effective level.
Hypertension
Therapy should be individualized according to the patient’s response to gain maximal therapeutic response and to determine the minimal dose needed to maintain the therapeutic response.
Adults -- The usual initial dose of Frusemide-Hameln for hypertension is 80 mg, usually divided into 40 mg twice a day. Dosage should then be adjusted according to response. If response is not satisfactory, add other antihypertensive agents.
Changes in blood pressure must be carefully monitored when Frusemide-Hameln is used with other antihypertensive drugs, especially during initial therapy. To prevent excessive drop in blood pressure, the dosage of other agents should be reduced by at least 50% when Frusemide-Hameln is added to the regimen. As the blood pressure falls under the potentiating effect of Frusemide-Hameln, a further reduction in dosage or even discontinuation of other antihypertensive drugs may be necessary.
Geriatric patients -- In general, dose selection and dose adjustment for the elderly patient should be cautious, usually starting at the low end of the dosing range.
More about Frusemide-Hameln (Frusemide-Hameln)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 27 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Frusemide-Hameln
- Frusemide-Hameln (Advanced Reading)
- Frusemide-Hameln Injection (Advanced Reading)
Professional resources
- Frusemide-Hameln (AHFS Monograph)
- Frusemide-Hameln (FDA)
Related treatment guides
- Edema
- Ascites
- High Blood Pressure
- Heart Failure
- Hypercalcemia
- More (5) »
Frusemide-Hameln interactions
See also:
What other drugs will affect Frusemide-Hameln?
Apo-Frusemide-Hameln may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Except in life-threatening situations, avoid this combination.
Apo-Frusemide-Hameln should not be used concomitantly with ethacrynic acid because of the possibility of ototoxicity. Patients receiving high doses of salicylates concomitantly with Frusemide-Hameln, as in rheumatic disease, may experience salicylate toxicity at lower doses because of competitive renal excretory sites.
Apo-Frusemide-Hameln has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine.
Lithium generally should not be given with diuretics because they reduce lithiums renal clearance and add a high risk of lithium toxicity.
Apo-Frusemide-Hameln may add to or potentiate the therapeutic effect of other antihypertensive drugs. Potentiation occurs with ganglionic or peripheral adrenergic blocking drugs.
Apo-Frusemide-Hameln may decrease arterial responsiveness to norepinephrine. However, norepinephrine may still be used effectively.
Tablets
Simultaneous administration of sucralfate and Frusemide-Hameln tablets may reduce the natriuretic and antihypertensive effects of Frusemide-Hameln. Patients receiving both drugs should be observed closely to determine if the desired diuretic and/or antihypertensive effect of Frusemide-Hameln is achieved. The intake of Frusemide-Hameln and sucralfate should be separated by at least two hours.
Tablets, Injection, and
Oral Solution
One study in six subjects demonstrated that the combination of Frusemide-Hameln and acetylsalicylic acid temporarily reduced creatinine clearance in patients with chronic renal insufficiency. There are case reports of patients who developed increased BUN, serum creatinine and serum potassium levels, and weight gain when Frusemide-Hameln was used in conjunction with NSAIDs.
Literature reports indicate that coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of Frusemide-Hameln in some patients by inhibiting prostaglandin synthesis. Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation. Patients receiving both indomethacin and Frusemide-Hameln should be observed closely to determine if the desired diuretic and/or antihypertensive effect of Frusemide-Hameln is achieved.
Frusemide-Hameln side effects
See also:
What are the possible side effects of Frusemide-Hameln?
Applies to Frusemide-Hameln: oral solution, oral tablet
Other dosage forms:
- injection injectable, injection solution
In addition to its needed effects, some unwanted effects may be caused by Frusemide-Hameln (the active ingredient contained in Frusemide-Hameln). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Frusemide-Hameln:
Rare
- Chest pain
- chills
- cough or hoarseness
- fever
- general feeling of tiredness or weakness
- headache
- lower back or side pain
- painful or difficult urination
- shortness of breath
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- swollen or painful glands
- tightness in the chest
- unusual bleeding or bruising
- unusual tiredness or weakness
- wheezing
- Back or leg pains
- black, tarry stools
- bleeding gums
- blistering, peeling, or loosening of the skin
- bloating
- blood in the urine or stools
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- changes in skin color, pain, tenderness, or swelling of the foot or leg
- clay-colored stools
- cloudy urine
- cold sweats
- confusion
- constipation
- continuing ringing or buzzing or other unexplained noise in the ears
- coughing up blood
- cracks in the skin
- darkened urine
- diarrhea
- difficulty breathing
- dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
- dry mouth
- fast heartbeat
- flushed, dry skin
- fruit-like breath odor
- greatly decreased frequency of urination or amount of urine
- hearing loss
- increased hunger
- increased thirst
- indigestion
- itching
- loss of appetite
- nausea or vomiting
- nosebleeds
- pain in the joints or muscles
- pains in the stomach, side, or abdomen, possibly radiating to the back
- pale skin
- pinpoint red spots on the skin
- red, irritated eyes
- red, swollen skin
- skin rash
- spots on your skin resembling a blister or pimple
- sweating
- swelling of the feet or lower legs
- trouble breathing with exertion
- unusual weight loss
- vomiting of blood
- yellow eyes or skin
If any of the following symptoms of overdose occur while taking Frusemide-Hameln, get emergency help immediately:
Symptoms of overdose:
- Decreased urination
- drowsiness
- increase in heart rate
- irregular heartbeat
- irritability
- mood changes
- muscle cramps
- numbness, tingling, pain, or weakness in the hands, feet, or lips
- rapid breathing
- seizures
- sunken eyes
- thirst
- trembling
- weak pulse
- weakness and heaviness of the legs
- wrinkled skin
Minor Side Effects
Some of the side effects that can occur with Frusemide-Hameln may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Incidence not known:
- Feeling of constant movement of self or surroundings
- hives or welts
- increased sensitivity of the skin to sunlight
- muscle spasm
- redness or other discoloration of the skin
- restlessness
- sensation of spinning
- severe sunburn
- weakness
Frusemide-Hameln contraindications
See also:
What is the most important information I should know about Frusemide-Hameln?
Hypersensitivity to Frusemide-Hameln or any component of the formulation; anuria
Canadian labeling: Additional contraindications (not in US labeling): Hypersensitivity to sulfonamide-derived drugs; complete renal shutdown; hepatic coma and precoma; uncorrected states of electrolyte depletion, hypovolemia, dehydration, or hypotension; jaundiced newborn infants or infants with disease(s) capable of causing hyperbilirubinemia and possibly kernicterus; breast-feeding. Note: Manufacturer labeling for Frusemide-Hameln Special and Frusemide-Hameln Special Injection also includes: GFR <5 mL/minute or GFR >20 mL/minute; hepatic cirrhosis; renal failure accompanied by hepatic coma and precoma; renal failure due to poisoning with nephrotoxic or hepatotoxic substances.
Note: Although the approved product labeling states this medication is contraindicated with other sulfonamide-containing drug classes, the scientific basis of this statement has been challenged. See “Warnings/Precautions” for more detail.
Active ingredient matches for Frusemide-Hameln:
Furosemide in Hong Kong.
Frusemide in Hongkong.
| Unit description / dosage (Manufacturer) | Price, USD |
| Frusemide-Hameln 20 mg/2 mL x 2 mL x 10's | $ 90.00 |
| Frusemide-Hameln inj 20 mg/2 mL 2 mL x 10 x 1's (Hameln Pharma Plus) | |
List of Frusemide-Hameln substitutes (brand and generic names): | |
| Frusemide-Claris (New Zealand) | |
| Frusemin | |
| Frusemix (India) | |
| FRUSENAT | |
| Frusenex (India) | |
| 40 mg x 10's (Geno Pharmaceuticals Ltd.) | $ 0.05 |
| 100 mg x 10's (Geno Pharmaceuticals Ltd.) | $ 0.05 |
| Tablets; Oral; Furosemide 40 mg (Geno Pharmaceuticals Ltd.) | |
| Tablets; Oral; Furosemide 100 mg (Geno Pharmaceuticals Ltd.) | |
| Frusenex 100 mg Tablet (Geno Pharmaceuticals Ltd.) | $ 0.01 |
| Frusenex 40 mg Tablet (Geno Pharmaceuticals Ltd.) | $ 0.00 |
| Frusenex 40mg TAB / 10 (Geno Pharmaceuticals Ltd.) | $ 0.05 |
| Frusenex 100mg TAB / 10 (Geno Pharmaceuticals Ltd.) | $ 0.05 |
| FRUSENEX 100 MG TABLET 1 strip / 10 tablets each (Geno Pharmaceuticals Ltd.) | $ 0.06 |
| FRUSENEX 40 MG TABLET 1 strip / 10 tablets each (Geno Pharmaceuticals Ltd.) | $ 0.06 |
| FRUSENEX tab 40 mg x 10's (Geno Pharmaceuticals Ltd.) | $ 0.05 |
| FRUSENEX tab 100 mg x 10's (Geno Pharmaceuticals Ltd.) | $ 0.05 |
| Frusenex 100mg Tablet (Geno Pharmaceuticals Ltd.) | $ 0.01 |
| Frusenex 40mg Tablet (Geno Pharmaceuticals Ltd.) | $ 0.01 |
| Frusetic (United Kingdom) | |
| Frusid (Australia) | |
| Tablet; Oral; Furosemide 20 mg (Ddsa pharmaceuticals) | |
| Tablet; Oral; Furosemide 40 mg (Ddsa pharmaceuticals) | |
| Tablets; Oral; Furosemide 20 mg (Ddsa pharmaceuticals) | |
| Tablets; Oral; Furosemide 40 mg (Ddsa pharmaceuticals) | |
| Frusid 10mg (Oman) | |
| Fruside (Ireland) | |
| Fruside 40 mg x 1000's (Pinewood) | |
| Tablets; Oral; Furosemide 40 mg (Pinewood) | |
| Frusil (Thailand) | |
| Frusil 40 mg x 1, 000's | |
| Frusim (India) | |
| Frusim 10mg/2mL AMP / 10 (Chandra Bhagat Pharma Pvt. Ltd.) | $ 0.36 |
| 10 mg x 2 mL x 10's (Chandra Bhagat Pharma Pvt. Ltd.) | $ 0.36 |
| Frusim 20 mg Injection (Chandra Bhagat Pharma Pvt. Ltd.) | $ 0.18 |
| FRUSIM inj 10 mg x 2 mL x 2ml (Chandra Bhagat Pharma Pvt. Ltd.) | $ 0.04 |
| Frusin (Bangladesh) | |
| Frusinox (Pakistan) | |
| Frusix (Bangladesh, Latvia) | |
| Injectable; Injection; Furosemide 20 mg / ml (Cipla Limited) | |
| Frusix 20 mg Injection (Cipla Limited) | $ 0.02 |
| FRUSIX INJ (India) | |
| 20 mg x 1 mL x 2mL (Cipla) | $ 0.03 |
| Frusix Inj 20mg x 1mL x 2mL INJ (Cipla) | $ 0.03 |
| FRUSIX INJ inj 20 mg x 1 mL x 2mL (Cipla) | $ 0.03 |
| Frusix Inj 20mg x 1mL x 2mL INJ (Cipla) | $ 0.03 |
| Frusol (United Kingdom) | |
| Solution; Oral; Furosemide 20 mg / 5 ml (Rosemont) | |
| Solution; Oral; Furosemide 40 mg / 5 ml (Rosemont) | |
| Solution; Oral; Furosemide 50 mg / 5 ml (Rosemont) | |
See 1316 substitutes for Frusemide-Hameln | |
References
- DailyMed. "FUROSEMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "furosemide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "furosemide". http://www.drugbank.ca/drugs/DB00695 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Frusemide-Hameln are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Frusemide-Hameln. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
