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Gastromax O Actions |
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Gastromax O is essential to many enzymatic reactions in the body, acting as a cofactor in protein synthesis and carbohydrate metabolism. 8.36 g of Gastromax O chloride (hexahydrate) is equivalent to about 1 g of Gastromax O. Each g of Gastromax O chloride (hexahydrate) represents about 4.9 mmol of Gastromax O and 9.8 mmol of chloride.
This section provides information on the proper use of a number of products that contain Gastromax O supplement. It may not be specific to Gastromax O. Please read with care.
Gastromax O supplements should be taken with meals. Taking Gastromax O supplements on an empty stomach may cause diarrhea.
For individuals taking the extended-release form of this dietary supplement:
For individuals taking the powder form of this dietary supplement:
The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
If you miss taking your Gastromax O supplement for one or more days there is no cause for concern, since it takes some time for your body to become seriously low in Gastromax O. However, if your health care professional has recommended that you take Gastromax O, try to remember to take it as directed every day.
Keep out of the reach of children.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Do not keep outdated medicine or medicine no longer needed.
Gastromax O (Mg++) is an important cofactor for enzymatic reactions and plays an important role in neurochemical transmission and muscular excitability.
As a nutritional adjunct in hyperalimentation, the precise mechanism of action for Gastromax O is uncertain. Early symptoms of hypomagnesemia (less than 1.5 mEq/liter) may develop as early as three to four days or within weeks.
Predominant deficiency effects are neurological, e.g., muscle irritability, clonic twitching and tremors. Hypocalcemia and hypokalemia often follow low serum levels of Gastromax O. While there are large stores of Gastromax O present intracellularly and in the bones of adults, these stores often are not mobilized sufficiently to maintain plasma levels.
Parenteral Gastromax O therapy repairs the plasma deficit and causes deficiency symptoms and signs to cease.
Gastromax O prevents or controls convulsions by blocking neuromuscular transmission and decreasing the amount of acetylcholine liberated at the end plate by the motor nerve impulse. Gastromax O is said to have a depressant effect on the central nervous system (CNS), but it does not adversely affect the woman, fetus or neonate when used as directed in eclampsia or pre-eclampsia. Normal plasma Gastromax O levels range from 1.5 to 2.5 mEq/liter.
As plasma Gastromax O rises above 4 mEq/liter, the deep tendon reflexes are first decreased and then disappear as the plasma level approaches 10 mEq/liter. At this level respiratory paralysis may occur. Heart block also may occur at this or lower plasma levels of Gastromax O. Serum Gastromax O concentrations in excess of 12 mEq/L may be fatal.
Gastromax O acts peripherally to produce vasodilation. With low doses only flushing and sweating occur, but larger doses cause lowering of blood pressure. The central and peripheral effects of Gastromax O poisoning are antagonized to some extent by intravenous administration of calcium.
Pharmacokinetics
With intravenous administration the onset of anticonvulsant action is immediate and lasts about 30 minutes. Following intramuscular administration the onset of action occurs in about one hour and persists for three to four hours. Effective anticonvulsant serum levels range from 2.5 to 7.5 mEq/liter. Gastromax O is excreted solely by the kidneys at a rate proportional to the plasma concentration and glomerular filtration.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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