What happens if I overdose Folic acid (Gefeleron)?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately.
Proper storage of Folic acid (Gefeleron):
Store Folic acid (Gefeleron) at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Folic acid (Gefeleron) out of the reach of children and away from pets.
Overdose of Folic acid (Gefeleron) in details
When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: mental/mood changes.
Notes
Do not share this medication with others.
Laboratory and/or medical tests (such as complete blood count, folate blood level, vitamin B-12 blood level) should be performed periodically to monitor your progress. Consult your doctor for more details.
Folate is naturally found in leafy green vegetables, organ meats (liver, kidney), citrus fruits, and other foods. Folic acid (Gefeleron) is added to enriched grain products such as bread, pasta, and cereal. Consult your doctor or dietician for a diet plan rich in folate/Folic acid (Gefeleron).
Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Storage
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
What should I avoid while taking Folic acid (Gefeleron)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Folic acid (Gefeleron) warnings
Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
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Use Folic acid (Gefeleron) IVAX with caution in patients with bronchial asthma, COPD, bronchitis, decompensated heart failure, diabetes, renal and / or liver failure, hyperthyroidism, depression, myasthenia gravis, psoriasis, occlusive peripheral vascular disease, pregnancy, lactation, elderly patients, children (efficacy and safety are not defined).
During the period of treatment it may been exacerbation of psoriasis.
When pheochromocytoma propranolol can be applied only after taking alpha-blockers.
After a lengthy course of treatment Folic acid (Gefeleron) IVAX should be lifted gradually, under medical supervision.
During treatment with this drug it should be avoided in the intravenous administration of verapamil, diltiazem.
A few days before the anesthesia it is necessary to stop taking propranolol or find a means of anesthesia with minimal negative inotropic effects.
Patients whose work requires more attention, the application of this medication outpatients should be addressed only after the evaluation of individual patient response.
What should I discuss with my healthcare provider before taking Folic acid (Gefeleron)?
Some medical conditions may interact with Folic acid (Gefeleron). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a long-term infection, seizure disorder (eg, epilepsy), or liver problems (eg, alcoholic cirrhosis), or if you are on kidney dialysis
if you drink alcohol regularly
if you have other types of anemia (eg, anemia due to low vitamin B levels)
Some MEDICINES MAY INTERACT with Folic acid (Gefeleron). Tell your health care provider if you are taking any other medicines, especially any of the following:
Fluorouracil because its actions and side effects may be increased by Folic acid (Gefeleron)
Hydantoins (eg, phenytoin) because their effectiveness may be decreased by Folic acid (Gefeleron)
Barbiturates (eg, phenobarbital), methotrexate, nitrofurantoin, phenytoin, primidone, or pyrimethamine because the effectiveness of Folic acid (Gefeleron) may be decreased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Folic acid (Gefeleron) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Folic acid (Gefeleron) precautions
Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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General
Folic acid (Gefeleron) in doses above 0.1 mg daily may obscure pernicious anemia in that hematologic remission can occur while neurologic manifestations remain progressive.
There is a potential danger in administering Folic acid (Gefeleron) to patients with undiagnosed anemia, since Folic acid (Gefeleron) may obscure the diagnosis of pernicious anemia by alleviating the hematologic manifestations of the disease while allowing the neurologic complications to progress. This may result in severe nervous system damage before the correct diagnosis is made. Adequate doses of vitamin B12 may prevent, halt, or improve the neurologic changes caused by pernicious anemia.
Drug Interactions
There is evidence that the anticonvulsant action of phenytoin is antagonized by Folic acid (Gefeleron). A patient whose epilepsy is completely controlled by phenytoin may require increased doses to prevent convulsions if Folic acid (Gefeleron) is given.
Folic deficiency may result from increased loss of folate, as in renal dialysis and/or interference with metabolism (e.g., Folic acid (Gefeleron) antagonists such as methotrexate); the administration of anticonvulsants, such as diphenylhydantoin, primidone, and barbiturates; alcohol consumption and, especially, alcoholic cirrhosis; and the administration of pyrimethamine and nitrofurantoin.
False low serum and red cell folate levels may occur if the patient has been taking antibiotics, such as tetracycline, which suppress the growth of Lactobacillus casei.
Carcinogenesis, Mutagenesis, Impairment of Fertility
Long-term studies in animals to evaluate carcinogenic potential and studies to evaluate the mutagenic potential or effect on fertility have not been conducted.
Pregnancy
Teratogenic Effects
Pregnancy Category A
Folic acid (Gefeleron) is usually indicated in the treatment of megaloblastic anemias of pregnancy. Folic acid (Gefeleron) requirements are markedly increased during pregnancy, and deficiency will result in fetal damage.
Studies in pregnant women have not shown that Folic acid (Gefeleron) increases the risk of fetal abnormalities if administered during pregnancy. If the drug is used during pregnancy, the possibility of fetal harm appears remote. Because studies cannot rule out the possibility of harm, however, Folic acid (Gefeleron) should be used during pregnancy only if clearly needed.
Nursing Mothers
Folic acid (Gefeleron) is excreted in the milk of lactating mothers. During lactation, Folic acid (Gefeleron) requirements are markedly increased; however, amounts present in human milk are adequate to fulfill infant requirements, although supplementation may be needed in lowbirth-weight infants, in those who are breast-fed by mothers with folic deficiency (50 mcg daily), or in those with infections or prolonged diarrhea.
What happens if I miss a dose of Folic acid (Gefeleron)?
When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
References
DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN 5'-PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).