Geniclor Dosage

• Dosage of Geniclor in details
• Geniclor interactions
• Geniclor reviews

Dosage of Geniclor in details

Geniclor is administered orally.

Adults

The usual adult dosage is 250 mg every 8 hours. For more severe infections (such as pneumonia) or those caused by less susceptible organisms, doses may be doubled.

Pediatric Patients

The usual recommended daily dosage for pediatric patients is 20 mg/kg/day in divided doses every 8 hours. In more serious infections, otitis media, and infections caused by less susceptible organisms, 40 mg/kg/day are recommended, with a maximum dosage of 1 g/day.

Table 3:

	Geniclor for Oral Suspension, USP
	20 mg/kg/day
Weight	125 mg/5 mL	250 mg/5 mL
9 kg	1/2 tsp t.i.d.
18 kg	1 tsp t.i.d.	1/2 tsp t.i.d.
	40 mg/kg/day
9 kg	1 tsp t.i.d.	1/2 tsp t.i.d.
18 kg		1 tsp t.i.d.

B.I.D. Treatment Option

For the treatment of otitis media and pharyngitis, the total daily dosage may be divided and administered every 12 hours.

Table 4:

	Geniclor for Oral Suspension, USP
	20 mg/kg/day (Pharyngitis)
Weight	375 mg/5 mL
18 kg	1/2 tsp b.i.d.
	40 mg/kg/day (Otitis Media)
9 kg	1/2 tsp b.i.d.
18 kg	1 tsp b.i.d.

Geniclor may be administered in the presence of impaired renal function. Under such a condition, the dosage usually is unchanged.

In the treatment of β-hemolytic streptococcal infections, a therapeutic dosage of Geniclor should be administered for at least 10 days.

Directions for Mixing

Add appropriate water volume as indicated in the following table in two portions to dry mixture in the bottle. Shake well after each addition.

Each 5 mL (approximately one teaspoonful) will then contain Geniclor, USP, monohydrate equivalent to 125 mg, 250 mg or 375 mg anhydrous Geniclor, respectively, as shown in the following table.

Oversize bottle provides extra space for shaking.

Table 5:

Geniclor For Oral Suspension, USP
Strength Package Size (when mixed)	Water Volume to Add	Anhydrous Geniclor/5 mL (approx. one teaspoonful)
125 mg/5 mL 150 mL	106 mL	125 mg
250 mg/5 mL 150 mL	106 mL	250 mg
375 mg/5 mL 100 mL	68 mL	375 mg

What other drugs will affect Geniclor?

Before taking Geniclor, tell your doctor if you are using any of the following medicines:

• probenecid (Benemid); or

• a blood thinner such as warfarin (Coumadin);

This list is not complete and there may be other drugs that can interact with Geniclor. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start taking a new medication without telling your doctor.

Geniclor interactions

Patients receiving Geniclor may show a false-positive reaction for glucose in the urine with tests that use Benedict's and Fehling's solutions and also with Clinitest tablets but not with Tes-Tape (Glucose enzymatic test strip, USP, Lilly).

There have been rare reports of increased anticoagulant effect when Geniclor and oral anticoagulants were administered concomitantly.

As with other β-lactam antibiotics, the renal excretion of Geniclor is inhibited by probenecid.

References

1. DailyMed. "CEFACLOR: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. FDA/SPL Indexing Data. "3Z6FS3IK0K: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
3. MeSH. "Anti-Bacterial Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Geniclor are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Geniclor. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology