Gestinol Uses

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Gestinol indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

triphasic oral contraceptive

Gestinol interactions

Concurrent use with hepatic enzyme inducers e.g. barbiturates, primidone, phenobarbitone, phenytoin, phenylbutazone, rifampicin, carbamazepine and griseofulvin may affect contraceptive efficacy. Short courses of broad-spectrum antibiotics may also reduce the efficacy of the oral contraceptive. Concurrent use with HIV protease and non-nucleoside reverse transcriptase inhibitors may affect hepatic metabolism of Gestodene (Gestinol) and/or ethinylestradiol. May increase plasma concentrations of ciclosporin and decrease the serum levels of lamotrigine. Concurrent use with felbamate may increase the clearance of Gestodene (Gestinol). Gestodene (Gestinol) may increase serum levels of buprenorphine. Co-trimoxazole, miconazole and etoricoxib may increase serum levels of ethinylestradiol. Aprepitant, modafinil and bosentan may reduce the serum levels of ethinylestradiol. Metabolism of omeprazole may be inhibited by ethinylestradiol. GI absorption of ethinylestradiol may be increased by concurrent admin of paracetamol.

Food Interaction

Concurrent treatment with St John’s wort may reduce efficacy of the oral contraceptive.

Gestinol side effects


Headaches, body wt changes, depressed/altered moods, breast pain or tenderness, changes in libido. GI disturbance such as nausea and abdominal pain.

Gestinol contraindications

Severe hepatic impairment, jaundice or persistent itching during a previous pregnancy, Dubin-Johnson syndrome, Rotor syndrome, previous or existing liver tumours. Personal or family history of venous thromboembolism (VTE). Risk factors for VTE. Sickle-cell anaemia, severe DM with vascular changes, lipid metabolism disorders, undiagnosed abnormal vaginal bleeding, history of herpes gestationis, worsening of otosclerosis during pregnancy. Exisiting or history of mammary or endometrial carcinoma. Pregnancy.

Active ingredient matches for Gestinol:

Ethinyl Estradiol/Gestodene in Brazil.


Ethinylestradiol/Gestodene in Brazil.

List of Gestinol substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Dragee; Oral; Ethinyl Estradiol 0.02 mg; Gestodene 0.075 mg
Dragee; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg
Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.02 mg; Gestodene 0.075 mg
Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg
Capsule; Oral; Ethinyl Estradiol 20 mcg; Gestodene 75 mcg (Sandoz)


  1. DailyMed. "ETHINYL ESTRADIOL; NORETHINDRONE ACETATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". (accessed September 17, 2018).
  2. PubChem. "ethinyl estradiol". (accessed September 17, 2018).
  3. PubChem. "GESTODENE". (accessed September 17, 2018).


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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