Gestoden Plus Uses

How do you administer this medicine?
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Gestoden Plus indications

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triphasic oral contraceptive

Gestoden Plus interactions

Concurrent use with hepatic enzyme inducers e.g. barbiturates, primidone, phenobarbitone, phenytoin, phenylbutazone, rifampicin, carbamazepine and griseofulvin may affect contraceptive efficacy. Short courses of broad-spectrum antibiotics may also reduce the efficacy of the oral contraceptive. Concurrent use with HIV protease and non-nucleoside reverse transcriptase inhibitors may affect hepatic metabolism of Gestodene (Gestoden Plus) and/or ethinylestradiol. May increase plasma concentrations of ciclosporin and decrease the serum levels of lamotrigine. Concurrent use with felbamate may increase the clearance of Gestodene (Gestoden Plus). Gestodene (Gestoden Plus) may increase serum levels of buprenorphine. Co-trimoxazole, miconazole and etoricoxib may increase serum levels of ethinylestradiol. Aprepitant, modafinil and bosentan may reduce the serum levels of ethinylestradiol. Metabolism of omeprazole may be inhibited by ethinylestradiol. GI absorption of ethinylestradiol may be increased by concurrent admin of paracetamol.

Food Interaction

Concurrent treatment with St John’s wort may reduce efficacy of the oral contraceptive.

Gestoden Plus side effects

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Headaches, body wt changes, depressed/altered moods, breast pain or tenderness, changes in libido. GI disturbance such as nausea and abdominal pain.

Gestoden Plus contraindications

Severe hepatic impairment, jaundice or persistent itching during a previous pregnancy, Dubin-Johnson syndrome, Rotor syndrome, previous or existing liver tumours. Personal or family history of venous thromboembolism (VTE). Risk factors for VTE. Sickle-cell anaemia, severe DM with vascular changes, lipid metabolism disorders, undiagnosed abnormal vaginal bleeding, history of herpes gestationis, worsening of otosclerosis during pregnancy. Exisiting or history of mammary or endometrial carcinoma. Pregnancy.

Active ingredient matches for Gestoden Plus:

Ethinyl Estradiol/Gestodene


Unit description / dosage (Manufacturer)Price, USD
Dragee; Oral; Ethinyl Estradiol 0.02 mg; Gestodene 0.075 mg
Dragee; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg

List of Gestoden Plus substitutes (brand and generic names):

Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.02 mg; Gestodene 0.075 mg
Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg
Dragee; Oral; Ethinyl Estradiol 0.02 mg; Gestodene 0.075 mg
Dragee; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg
Tablet, Sugar-Coated; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg (Schering)
Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.02 mg; Gestodene 0.075 mg
Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg
Tablet, Sugar-Coated; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg
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Tablet, Sugar-Coated; Oral; Ethinyl Estradiol 0.02 mg; Gestodene 0.75 mg
Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.015 mg; Gestodene 0.06 mg (Andromaco)
Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.02 mg; Gestodene 0.075 mg (Andromaco)
Tablet, Film-Coated; Oral; Ethinyl Estradiol 0.03 mg; Gestodene 0.075 mg (Andromaco)
6 Light Beige Tablets: Ethinyl Estradiol 30 mcg; Gestodene 50 mcg / 5 Brown Tablets: Ethinyl Estradiol 40 mcg; Gestodene 70 mcg / 10 Small White Tablets: Ethinyl Estradiol 30 mcg; Gestodene 100 mcg / 7 Larger White Tablets contains no active ingredients

References

  1. DailyMed. "ETHINYL ESTRADIOL; NORETHINDRONE ACETATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "ethinyl estradiol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "GESTODENE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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