Glucantime Uses

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Glucantime indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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This medication is used before an X-ray or similar tests (e.g., tomography) to help your doctor view on film, your throat (esophagus), stomach, and intestines more effectively. It may be used with other injectable products (IV contrast) as determined by your doctor.

Glucantime dosage

Dosage depends on the type & location of the investigation.

Glucantime interactions

Hypersensitivity reactions can be aggravated in patients on beta-blockers, particularly in people with bronchial asthma. Moreover, it should be considered that patients on beta-blockers may be refractory to standard treatment of hypersensitivity reactions with beta-agonists.

The prevalence of delayed reactions (eg fever, rash, flu-like symptoms, joint pain and pruritus) to contrast media is higher in patients who have received interleukin.

The presence of renal damage in diabetic patients is one of the factors predisposing to renal impairment following contrast media administration. This may precipitate lactic acidosis in patients who are taking biguanides. As a precaution, biguanides should be stopped 48 hours prior to the contrast agent examination and reinstated only after control of renal function has been regained.

Interference with diagnostic tests

Following the administration of iodinated contrast media, the capacity of the thyroid tissue to take up radioisotopes for diagnosing disorders of the thyroid is reduced for up to two weeks, and even longer in individual cases.

Pregnancy and lactation

Reproduction-toxicological studies with Glucantime- or sodium amidotrizoate gave no indication of a teratogenic or other embryotoxic potential following an inadvertent administration of Urografin during pregnancy.

It has not been sufficiently demonstrated that contrast media are safe for use in pregnant patients. Since, wherever possible, radiation exposure should be avoided during pregnancy, the benefits of any X-ray examination, with or without contrast media, should be carefully weighed against the possible risk.

Renally eliminated contrast media like Urografin enter the breast milk in only very small amounts.

Limited data suggest that the risk to the suckling infant of administering salts of diatrizoic acid to its mother is low. Breastfeeding is probably safe.

Glucantime side effects

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Intravascular use

Side effects in association with the use of iodinated contrast media are usually mild to moderate and transient in nature. However, severe and life-threatening reactions as well as deaths have been reported. The prevalence of adverse drug reactions in patients receiving ionic contrast media is reported to be over 12% compared to over 3% for non-ionics.

Nausea, vomiting, a sensation of pain and a general feeling of warmth are the most frequently recorded reactions.

Anaphylactoid reactions/hypersensitivity

Angioedema, conjunctivitis, coughing, pruritus, rhinitis, sneezing and urticaria have been reported commonly. These reactions which can occur irrespective of the amount administered and the mode of administration, may be the first signs of an incipient state of shock. Administration of the contrast medium must be discontinued immediately and –if necessary –specific therapy instituted via a venous access.

Severe reactions requiring emergency treatment can occur in the form of a circulatory reaction accompanied by peripheral vasodilatation and subsequent hypotension, reflex tachycardia, dyspnoea, agitation, confusion and cyanosis possibly leading to unconsciousness.

Hypotension, bronchospasm and laryngeal spasm or oedema occur uncommonly.

Delayed contrast medium reactions are rare.

Body as a whole

Heat sensations and headache have been reported as being common. Malaise, chills or sweating and vasovagal reactions are uncommon.

In rare cases alterations in body temperature and swelling of salivary glands are possible.

Respiratory

Transient disturbance in respiratory rate, dyspnoea and respiratory distress and coughing are common.

Respiratory arrest and pulmonary oedema are rare reactions.

Cardiovascular

Clinically relevant transient disturbance in heart rate, blood pressure, disturbance in cardiac rhythm or function and cardiac arrest are uncommon.

Severe reactions requiring emergency treatment can occur in the form of a circulatory reaction accompanied by peripheral vasodilatation and subsequent hypotension, reflex tachycardia, dyspnoea, agitation, confusion and cyanosis possibly leading to unconsciousness.

Serious thromboembolic events causing myocardial infarction have been reported in rare cases.

Gastrointestinal

Nausea and vomiting are common reactions. Abdominal pain has been reported as being uncommon.

Cerebrovascular

Cerebral angiography and other procedures in which the contrast medium reaches the brain in high concentrations with the arterial blood can be accompanied by transient neurological complications such as: dizziness, headache, agitation or confusion, amnesia, disturbed speech, vision, hearing, convulsions, tremor, paresis/paralysis, photophobia, temporary blindness, coma, and somnolence are uncommon.

Serious, in isolated cases fatal, thromboembolic events causing stroke have been reported on rare occasions.

Renal

In rare cases renal impairment or failure have been reported.

Skin

Mild angioedema, flush reaction with vasodilatation, urticaria, pruritus and erythema have been commonly observed.

Toxic skin reactions such as the mucocutaneous syndrome (eg Stevens-Johnson

Glucantime contraindications

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Hypersensitivity to antihistamines,

History of agranulocytosis,

Risk of urinary retention due to disorders - Risk of glaucoma angle closure.

Active ingredient matches for Glucantime:

Meglumine in Brazil, Costa Rica, Dominican Republic, Ecuador, El Salvador, France, Georgia, Guatemala, Honduras, Italy, Nicaragua, Panama, Portugal, Spain, Tunisia, Venezuela.

Meglumine antimonate in Spain, Brazil, Venezuela, France.


Unit description / dosage (Manufacturer)Price, USD
Injectable; Injection; Meglumine Antimoniate 300 mg / ml

List of Glucantime substitutes (brand and generic names):

50ml (Zydus (G.Rem))$ 6.70
ANGIOGRAFIN 65% INJ inj 0.65 g x 1 mL x 20ml (Zydus (G.Rem))$ 2.36
ANGIOGRAFIN 65% INJ inj 0.65 g x 1 mL x 50ml (Zydus (G.Rem))$ 6.70
Injectable; IV / Infusion; Meglumine Iotroxate 105 mg / ml (Schering)
60 % x 20ml (Dabur)$ 1.89
60 % x 50ml (Dabur)$ 4.73
76 % x 100ml (Dabur)$ 11.54
76 % x 20ml (Dabur)$ 2.33
76 % x 50ml (Dabur)$ 6.06
Contrastin Inj Meglumine 125.46 mg, sodiumdiatrizoate 471.48 mg, iodine5.84 g. INJ / 20ml (Dabur)$ 1.89
Contrastin Inj Meglumine 125.46 mg, sodiumdiatrizoate 471.48 mg, iodine5.84 g. INJ / 50ml (Dabur)$ 4.73
Contrastin Inj Meglumine 159.24 mg, sodiumdiatrizoate 597.3 mg, iodine7.4 g. INJ / 100ml (Dabur)$ 11.54
Contrastin Inj Meglumine 159.24 mg, sodiumdiatrizoate 597.3 mg, iodine7.4 g. INJ / 20ml (Dabur)$ 2.33
Contrastin Inj Meglumine 159.24 mg, sodiumdiatrizoate 597.3 mg, iodine7.4 g. INJ / 50ml (Dabur)$ 6.06
CONTRASTIN INJ inj 20ml (Dabur)$ 2.33
CONTRASTIN INJ inj 50ml (Dabur)$ 6.06
CONTRASTIN INJ inj 100ml (Dabur)$ 11.54
Contrastin Inj Meglumine 125.46 mg, sodiumdiatrizoate 471.48 mg, iodine5.84 g. INJ / 20ml (Dabur)$ 1.89
Contrastin Inj Meglumine 125.46 mg, sodiumdiatrizoate 471.48 mg, iodine5.84 g. INJ / 50ml (Dabur)$ 4.73
Contrastin Inj Meglumine 159.24 mg, sodiumdiatrizoate 597.3 mg, iodine7.4 g. INJ / 100ml (Dabur)$ 11.54
Contrastin Inj Meglumine 159.24 mg, sodiumdiatrizoate 597.3 mg, iodine7.4 g. INJ / 20ml (Dabur)$ 2.33
Contrastin Inj Meglumine 159.24 mg, sodiumdiatrizoate 597.3 mg, iodine7.4 g. INJ / 50ml (Dabur)$ 6.06
Syrup; Oral; Meglumine Benzoate 390 mg; Polysorbate 20 45 mg; Promethazine Hydrochloride 7.5 mg
Meglumine 500 mg
Meglumine 500 mg
Meglumine 500 mg
Injectable; Injection; Meglumine Sodium Succinate 15 mg / ml (Polisan)
Reamberin 1 Bottle 400 mL (Polisan)
Injectable; Injection; Meglumine Sodium Succinate 15 mg / ml
Injectable; Injection; Meglumine Ioxitalamate 66.03%

Reviews

The results of a survey conducted on ndrugs.com for Glucantime are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Glucantime. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

4 consumers reported useful

Was the Glucantime drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful3
75.0%
Not useful1
25.0%


3 consumers reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Glucantime drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive2
66.7%
Not expensive1
33.3%


6 consumers reported time for results

To what extent do I have to use Glucantime before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Glucantime. To get the time effectiveness of using Glucantime drug by other patients, please click here.
Users%
1 month3
50.0%
1 day2
33.3%
3 month1
16.7%


12 consumers reported age

Users%
46-603
25.0%
1-53
25.0%
30-452
16.7%
16-292
16.7%
6-151
8.3%
> 601
8.3%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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