Grammicin Ear Drops Uses

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What is Grammicin Ear Drops?

Treating surface eye infections caused by certain bacteria.

Grammicin Ear Drops is a topical antibiotic. It works by slowing the growth of, or killing, sensitive bacteria.

Grammicin Ear Drops indications

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Primary skin infections: Impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum. Secondary skin infections: Infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis (including poison ivy), infected excoriations, and bacterial superinfections of fungal or viral infections. Please Note: Grammicin Ear Drops is a bactericidal agent that is not effective against viruses or fungi in skin infections. It is useful in the treatment of infected skin cysts and certain other skin abscesses when preceded by incision and drainage to permit adequate contact between the antibiotic and the infecting bacteria. Good results have been obtained in the treatment of infected stasis and other skin ulcers, infected superficial burns, paronychia, infected insect bites and stings, infected lacerations and abrasions, and wounds from minor surgery. Patients sensitive to neomycin can be treated with Grammicin Ear Drops, although regular observation of patients sensitive to topical antibiotics is advisable when such patients are treated with any topical antibiotic. Grammicin Ear Drops Cream USP, 0.1% is recommended for wet, oozing primary infections, and greasy, secondary infections, such as pustular acne or infected seborrheic dermatitis. Grammicin Ear Drops ointment helps retain moisture and has been useful in infection on dry eczematous or psoriatic skin. If a water-washable preparation is desired, the cream is preferable. Grammicin Ear Drops Cream USP, 0.1% has been used successfully in infants over one year of age, as well as in adults and children.

How should I use Grammicin Ear Drops?

Use Grammicin Ear Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Grammicin Ear Drops.

Uses of Grammicin Ear Drops in details

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This medication is used to treat minor skin infections (such as impetigo, folliculitis) or minor infections related to some skin conditions (such as eczema, psoriasis, minor burns/cuts/wounds). Grammicin Ear Drops works by stopping the growth of certain bacteria. It belongs to a class of drugs known as aminoglycoside antibiotics.

This antibiotic only treats bacterial infections. It will not work for virus or fungus infections. Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

How to use Grammicin Ear Drops topical

This medication is for use on the skin only.

Wash your hands before using. Clean and dry the affected area as directed. If you are treating impetigo, remove any dried, crusty skin to increase contact between the antibiotic and the infected area. Then gently apply a small amount of medication in a thin layer as directed by your doctor, usually 3 to 4 times a day. You may cover the area with a sterile gauze bandage if so directed. Keep the infected area clean. Wash your hands after use, unless you are using this product to treat the hands.

Avoid getting this medication in your eyes, nose, or mouth. If this occurs, wipe off the medication and rinse thoroughly with water.

Dosage and length of treatment is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day. Do not apply large amounts of this medication, use it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects may increase.

Continue to use this medication for the full length of treatment prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

Tell your doctor if your skin infection persists or if it worsens.

Grammicin Ear Drops description

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Grammicin Ear Drops also contains the following ingredients: Methyl paraben 1.8 mg, propyl paraben 0.2 mg, sodium bisulfite 3.2 mg, disodium ethylenediaminetetraacetate 0.1 mg and water for injection.

Grammicin Ear Drops injection is a sterile solution of Grammicin Ear Drops water for injection. It contains the equivalent of not less than 90% and not more than 125% of the labeled amount of Grammicin Ear Drops. It may contain suitable buffers, preservatives, sequestering agents, unless it is intended for intrathecal use, in which case it contains only suitable tonicity agents.

Grammicin Ear Drops dosage

A small amount of Grammicin Ear Drops Cream USP, 0.1% should be applied gently to lesions three or four times a day. The area treated may be covered with a gauze dressing if desired. In impetigo contagiosa, the crusts should be removed before application of Grammicin Ear Drops Cream USP, 0.1% to permit maximum contact between the antibiotic and the infection. Care should be exercised to avoid further contamination of the infected skin. Infected stasis ulcers have responded well to Grammicin Ear Drops under gelatin packing.

Grammicin Ear Drops interactions

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What other drugs will affect Grammicin Ear Drops?

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The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this drug include: aminoglycoside antibiotics given by injection (such as amikacin, Grammicin Ear Drops, tobramycin).

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

Grammicin Ear Drops side effects

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What are the possible side effects of Grammicin Ear Drops?

In patients with dermatoses treated with Grammicin Ear Drops, irritation (erythema and pruritus) that did not usually require discontinuance of treatment has been reported in a small percentage of cases. There was no evidence of irritation or sensitization, however, in any of these patients patch-tested subsequently with Grammicin Ear Drops on normal skin. Possible photosensitization has been reported in several patients but could not be elicited in these patients by reapplication of Grammicin Ear Drops followed by exposure to ultraviolet radiation.

Grammicin Ear Drops contraindications

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What is the most important information I should know about Grammicin Ear Drops?

Grammicin Ear Drops Sterile Ophthalmic Solution is contraindicated in patients with known hypersensitivity to any of the components.

Active ingredient matches for Grammicin Ear Drops:

Gentamicin sulfate in Thailand.


List of Grammicin Ear Drops substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Gentamycin Ophth Oint 3 mg/1 g x 5 g
Gentamycin Ophth Soln 3 mg/1 mL x 3 mL
Gentamycin Ophth Soln 3 mg/1 mL x 5 mL
Gentamycin Ophthalmic / Wu-Fu 3 mg/1 mL x 5 mL
Gentamycin Sulfate Shandong 80 mg/2 mL x 10 tube 2mL
Gentamytrex Ophtiole 5 mg/1 mL x 5 mL
Gentamytrex Ophtiole 5 mg/1 mL x 5 mL x 1's
Gentrobex 40 mg/1 mL x 10's
Migentax 40 mg/1 mL x 2 mL x 10's (Geofman)
Obogen / amp 40 mg/1 mL x 2 mL x 10's (Oboi)
Opthagen 0.3 % x 5 mL (Pascual)
Ottogenta Cream 0.1 % x 5 g x 1's$ 0.66
Phil Pharmawealth/Karnataka Gentamicin / vial 40 mg/1 mL x 2 mL x 50's
Refobacin Bone Cement R 40 g x 2's (Biomet)
Refobacin Bone Cement R 20 mL x 2's (Biomet)
Ridhay 0.3 % w/v x 1 Bottle 10 mL
Rotexmedica Gentamicin 1 tube
Sagestam Ear Drops 3 mg/1 mL x 5 mL x 1's (Sanbe Vision)$ 2.02
Sagestam Eye Drops 3 mg/1 mL x 5 mL x 1's$ 2.02
Salticin Cream 1 mg/1 g x 5 g$ 1.18
T P Gentamicin Sulfate 80 mg/2 mL x 10 tube
T P Gentamicin Sulfate 80 mg/2 mL x 50 tube
Topigen Eye Drops 3 mg/1 mL x 5 mL x 1's$ 4.36

References

  1. DailyMed. "GENTAMICIN SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "gentamicin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "gentamicin". http://www.drugbank.ca/drugs/DB00798 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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