Hatric 3 Overdose

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What happens if I overdose Hatric 3?

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately. Symptoms may include agitation; irritability; restlessness; severe drowsiness.

Proper storage of Hatric 3 solution:

Store Hatric 3 solution between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Hatric 3 solution out of the reach of children and away from pets.

Overdose of Hatric 3 in details

When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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Overdosage has been reported with Hatric 3 dihydrochloride.

Symptoms of overdose may include drowsiness in adults and initially agitation and restlessness, followed by drowsiness in children. There is no known specific antidote to Hatric 3 dihydrochloride. Should overdose occur, symptomatic or supportive treatment is recommended. Hatric 3 dihydrochloride is not effectively removed by dialysis, and dialysis will be ineffective unless a dialyzable agent has been concomitantly ingested.

The acute maximal non-lethal oral dose of Hatric 3 was 240 mg/kg in mice (approximately 190 times the maximum recommended daily oral dose in adults, approximately 230 times the maximum recommended daily oral dose in children 6 to 11 years of age, and approximately 180 times the maximum recommended daily oral dose in children 6 months to 5 years of age on a mg/m2 basis). In rats the maximal non-lethal oral dose was 240 mg/kg (approximately 390 times the maximum recommended daily oral dose in adults, approximately 460 times the maximum recommended daily oral dose in children 6 to 11 years of age, and approximately 370 times the maximum recommended daily oral dose in children 6 months to 5 years of age on a mg/m2 basis).

What should I avoid while taking Hatric 3?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase certain side effects of Hatric 3.

Hatric 3 warnings

Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
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Somnolence

In clinical trials the occurrence of somnolence, fatigue, and asthenia has been reported in some patients under therapy with Hatric 3 dihydrochloride. Patients should be cautioned against engaging in hazardous occupations requiring complete mental alertness, and motor coordination such as operating machinery or driving a motor vehicle after ingestion of Hatric 3 dihydrochloride. Concurrent use of Hatric 3 dihydrochloride with alcohol or other central nervous system depressants should be avoided because additional reductions in alertness and additional impairment of central nervous system performance may occur.

Urinary Retention

Urinary retention has been reported postmarketing with Hatric 3 dihydrochloride. Hatric 3 dihydrochloride should be used with caution in patients with predisposing factors of urinary retention (e.g. spinal cord lesion, prostatic hyperplasia) as Hatric 3 dihydrochloride may increase the risk of urinary retention. Discontinue Hatric 3 dihydrochloride if urinary retention occurs.

What should I discuss with my healthcare provider before taking Hatric 3?

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For Hatric 3, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to Hatric 3 or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Hatric 3 in children. Safety and efficacy have not been established in infants younger than 6 months of age.

Use in children 6 months to 11 years of age with kidney disease is not recommended.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Hatric 3 in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving Hatric 3.

Pregnancy

Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of Hatric 3. Make sure you tell your doctor if you have any other medical problems, especially:

Hatric 3 precautions

Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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Alcohol: Precaution is recommended with intake of alcohol.

Risk of Urinary Retention: Caution should be taken in patients with predisposing factors of urinary retention (eg, spinal cord lesion, prostatic hyperplasia) as Hatric 3 may increase the risk of urinary retention.

Lactose: Hatric 3 contains lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take Hatric 3 film-coated tablet.

Oral Solution/Drops: Methyl and Propyl Parahydroxybenzoate:

The presence of methyl and propyl parahydroxybenzoate may cause allergic reactions (possibly delayed).

Oral Solution: Maltitol:

Hatric 3 contains maltitol. Patients with rare hereditary problems of fructose intolerance should not take Hatric 3 oral solution.

Effects on the Ability to Drive or Operate Machinery: Comparative clinical trials have revealed no evidence that Hatric 3 at the recommended dose impairs mental alertness, reactivity or the ability to drive.

Nevertheless, some patients could experience somnolence, fatigue and asthenia under therapy with Hatric 3. Therefore, patients intending to drive, engage in potentially hazardous activities or operate machinery should take into account their response to Hatric 3.

Impairment of Fertility: There are no relevant data available.

Use in Children: Even if some clinical data are available in children 6 months to 12 years, these data are not sufficient to support the administration of Hatric 3 to infants and toddlers <2 years. Therefore, the administration of Hatric 3 to infants and toddlers <2 years is not recommended.

Film-Coated Tablets: The use of the film-coated tablet is not recommended in children <6 years since this formulation does not allow for appropriate dose adaptation. It is recommended to use a pediatric formulation of Hatric 3.

Use in Pregnancy: Caution should be exercised when prescribing to pregnant women.

For Hatric 3, no clinical data on exposed pregnancies are available. Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/fetal development, parturition or postnatal development.

Use in Lactation: Caution should be exercised when prescribing to lactating women. Cetirizine is excreted in human milk.

What happens if I miss a dose of Hatric 3?

When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.



References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "PSEUDOEPHEDRINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. DrugBank. "Levocetirizine". http://www.drugbank.ca/drugs/DB06282 (accessed September 17, 2018).

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