Hemostan Dosage

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Dosage of Hemostan in details

The dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
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Hemostan Dosage

Applies to the following strength(s): 500 mg; 100 mg/mL; 650 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Bleeding

For the treatment of cyclic heavy menstrual bleeding:

1,300 mg (two 650 mg tablets) orally three times a day (3,900 mg/day) for a maximum of 5 days during monthly menstruation.

For patients with hemophilia for short-term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction:

Immediately before dental extraction in patients with hemophilia, administer 10 mg per kg body weight intravenously. Following surgery, a dose of 10 mg per kg body weight intravenously three to four times daily, may be used for 2 to 8 days.

Usual Pediatric Dose for Bleeding

Hemostan has had limited use in pediatric patients, principally in connection with tooth extraction. The limited data suggest that dosing instructions for adults can be used for pediatric patients needing therapy.

For patients with hemophilia for short-term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction:

Immediately before dental extraction: 10 mg per kg body weight intravenously

Following surgery: 10 mg per kg body weight intravenously three to four times daily, may be used for 2 to 8 days.

Surgery for congenital heart disease (to reduce perioperative blood loss and need for transfusions):

(not FDA approved, limited data available, dose not established, variable dosing regimens reported)

2 months to 15 years:

loading dose: 100 mg/kg intravenously, followed by 10 mg/kg/hour infusion (continued until ICU transport) and 100 mg/kg priming dose when bypass initiated;

or

loading dose: 10 mg/kg intravenously, priming dose: 10 mg/kg and 10 mg/kg after protamine.

Surgery for scoliosis (to reduce perioperative blood loss and need for transfusions):

(not FDA approved, limited data available, dose not established, variable dosing regimens reported)

8 to 18 years:

loading dose: 100 mg/kg intravenously, followed by infusion: 10 mg/kg/hour until skin closure

or

loading dose: 20 mg/kg intravenously, followed by 10 mg/kg/hour infusion

or

loading dose: 10 mg/kg intravenously and 1 mg/kg/hour infusion.

For the treatment of cyclic heavy menstrual bleeding (ages 12 to less than 18):

1,300 mg (two 650 mg tablets) orally three times a day (3,900 mg/day) for a maximum of 5 days during monthly menstruation.

Renal Dose Adjustments

Oral

:

Serum creatinine above 1.4 mg/dL and less than or equal to 2.8 mg/dL:

1300 mg (two 650 mg tablets) orally two times a day for a maximum of 5 days during menstruation.

Serum creatinine above 2.8 mg/dL and less than or equal to 5.7 mg/dL:

1300 mg (two 650 mg tablets) orally once a day for a maximum of 5 days during menstruation.

Serum creatinine above 5.7 mg/dL:

650 mg (one 650 mg tablet) orally once a day for a maximum of 5 days during menstruation.

Intravenous

:

Serum creatinine 1.36 to 2.83 mg/dL:

10 mg/kg intravenously twice a day.

Serum creatinine 2.83 to 5.66 mg/dL:

10 mg/kg intravenously once a day.

Serum creatinine greater than 5.66 mg/dL:

5 mg/kg intravenously every 24 hours.

Liver Dose Adjustments

No dose adjustment is needed in patients with hepatic impairment.

Dialysis

Data not available

More about Hemostan

Consumer resources

Professional resources

Related treatment guides

What other drugs will affect Hemostan?

Tell your doctor about all other medicines you use, especially:

This list is not complete and other drugs may interact with Hemostan. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Hemostan interactions

Interactions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Hemostan, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
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Contraindications for Co-Administration: Hemostan should not be co-adminstered with thrombin. Co-administration may cause a thrombosis tendency. It increases the tendency towards thrombosis due to the thrombogenic property of Hemostan.

Precautions for Co-Administration: Hemostan should be administered with care when co-administered with the following drugs.

Hemocoagulase: Co-administration at high doses may cause a thrombosis tendency. Due to the antiplasmin action of Hemostan, fibrin clots formed by hemocoagulase may persist in the blood stream for a relatively long period of time, which may result in a prolonged thrombotic state.

Batroxobin: Co-administration may cause thromboembolism. Hemostan inhibits the decomposition of desA fibrin polymer produced by batroxobin.

Coagulation Factor Agents (Eptacog-α): Coagulation may be further activated at sites with enhanced local fibrinolysis eg, the oral cavity. Coagulation factors exert hemostatic actions by activating the coagulation system, where as Hemostan exerts hemostatic actions by inhibiting the fibrinolytic system.


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References

  1. DailyMed. "TRANEXAMIC ACID: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. FDA/SPL Indexing Data. "37YD696II6: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
  3. MeSH. "Antifibrinolytic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Hemostan are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Hemostan. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

24 consumers reported frequency of use

How frequently do I need to take Hemostan?
It was reported by ndrugs.com website users that Hemostan should ideally be taken 3 times in a day as the most common frequency of the Hemostan. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Hemostan should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
Users%
3 times in a day13
54.2%
Once in a day4
16.7%
Twice in a day4
16.7%
4 times in a day3
12.5%


22 consumers reported doses

What doses of Hemostan drug you have used?
The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Hemostan drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
Users%
201-500mg12
54.5%
501mg-1g8
36.4%
11-50mg1
4.5%
101-200mg1
4.5%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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