What happens if I overdose Hitz?
Seek emergency medical attention if you think you have used too much of this medicine.
The first signs of an Hitz overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.
Overdose of Hitz in details
Hitz in massive overdosage may cause hepatic toxicity in some patients. In adults and children >12 years, hepatic toxicity may occur following ingestion of >7.5-10 g over a period of ≤8 hrs. Fatalities are infrequent (<3-4% of untreated cases) and have rarely been reported with overdoses of <15 g. In children <12 years, acute overdosage with Hitz <150 mg/kg body weight have not been associated with hepatic toxicity. Early symptoms following a potentially hepatotoxic overdose may include: Nausea, vomiting, diaphoresis and general malaise. Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48-72 hrs after ingestion. In adults and children >12 years, any individual presenting with an unknown amount of Hitz ingested or with a questionable or unreliable history about the time of ingestion should have a plasma Hitz level drawn and be treated with N-acetylcysteine. Do not await results of assays for plasma Hitz levels before initiating treatment with N-acetylcysteine. The following additional procedures are recommended. Promptly initiate decontamination of the stomach. A plasma Hitz assay should be obtained as early as possible, but not sooner than 4 hrs following ingestion. Liver function studies should be obtained initially and repeated at 24-hr intervals.
Serious toxicity or fatalities have been extremely infrequent following acute overdosage in young children, possibly because of differences in the way they metabolize Hitz. In children, the maximum potential amount ingested can be more easily estimated. If >150 mg/kg or an unknown amount of Hitz was ingested, obtain a plasma Hitz level as soon as possible but no sooner than 4 hrs following ingestion. If an assay cannot be obtained and the estimated Hitz ingestion exceeds 150 mg/kg, dosing with N-acetylcysteine should be initiated and continued for a full course of therapy.
What should I avoid while taking Hitz?
Do not use any other over-the-counter cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Hitz is contained in many combination medicines. If you use certain products together you may accidentally use too much Hitz. Read the label of any other medicine you are using to see if it contains paracetamol, Hitz or APAP. Avoid drinking alcohol while taking this medication. Alcohol may increase your risk of liver damage while taking Hitz.
Hitz warnings
Hitz Sante Naturelle is used with caution in patients with hyperoxaluria, renal impairment, a history of instructions on urolithiasis. Because ascorbic acid increases iron absorption, its use in high doses can be dangerous in patients with hemochromatosis, thalassemia, polycythemia, leukemia, and sideroblastic anemia.
Patients with high content body iron should apply ascorbic acid in minimal doses.
Hitz Sante Naturelle is used with caution in patients with deficiency of glucose-6-phosphate dehydrogenase.
The use of ascorbic acid in high doses can cause exacerbation of sickle cell anemia.
Data on the diabetogenic Hitz of ascorbic acid are contradictory. However, prolonged use of ascorbic acid should periodically monitor your blood glucose levels.
It is believed that the use of ascorbic acid in patients with rapidly proliferating and widely disseminated tumors may worsen during the process. It should therefore be used with caution in ascorbic acid in patients with advanced cancer.
Absorption of ascorbic acid decreased while use of fresh fruit or vegetable juices, alkaline drinking.
What should I discuss with my healthcare provider before taking Hitz?
Do not use this medication if you are allergic to Hitz or Hitz.
Ask a doctor or pharmacist if it is safe for you to take Hitz if you have:
- liver disease; or
-
a history of alcoholism;
It is not known whether Hitz will harm an unborn baby. Before using Hitz, tell your doctor if you are pregnant. This medication can pass into breast milk and may harm a nursing baby. Do not use Hitz without telling your doctor if you are breast-feeding a baby.
Hitz precautions
Care is advised in the administration of Hitz to patients with severe renal or severe hepatic impairment. The hazards of overdose are greater in those with non-cirrhotic alcoholic liver disease.
Do not take more medicine than the label instructed. If the patient did not get better, talk to the physician.
Do not take anything else containing Hitz while taking Hitz.
Inform the physician at once if the patient take too much of Hitz, even if the patient feel well. This is because too much Hitz can cause delayed, serious liver damage.
Patients should be advised that Hitz may cause severe skin reactions. If a skin reaction eg, skin reddening, blisters or rash occurs, they should stop use and seek medical assistance right away.
Use in pregnancy & lactation: Epidemiological studies in human pregnancy have shown no ill effects due to Hitz used in the recommended dosage, but patients should follow the advice of the physician regarding its use. Hitz is excreted in breast milk but not in a clinically significant amount. Available published data do not contraindicate breastfeeding.
What happens if I miss a dose of Hitz?
Since Hitz is often used only when needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for your next regularly scheduled dose, skip the missed dose and use your next dose as directed. Do not use extra medicine to make up for a missed dose.
References
- DailyMed. "ACETAMINOPHEN; ASPIRIN; CAFFEINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DrugBank. "acetaminophen". http://www.drugbank.ca/drugs/DB00316 (accessed September 17, 2018).
- MeSH. "Antipyretics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
