Hydrocortisone Acetate Suppositories Overdose

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What happens if I overdose Hydrocortisone Acetate Suppositories?

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately. Hydrocortisone Acetate Suppositories suppositories may be harmful if swallowed.

Proper storage of Hydrocortisone Acetate Suppositories suppositories:

Store Hydrocortisone Acetate Suppositories suppositories at room temperature, below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not freeze. Do not store in the bathroom. Keep Hydrocortisone Acetate Suppositories suppositories out of the reach of children and away from pets.

Overdose of Hydrocortisone Acetate Suppositories in details

infoWhen a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Laboratory and/or medical tests (e.g., cortisol levels) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

This medication has been prescribed for your current condition only. Do not use it later for another condition unless told to do so by your doctor. A different medication may be necessary in that case.

Missed Dose

If you miss a dose, use it as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature between 68-77 degrees F (20-25 degrees C). Do not refrigerate. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

What should I avoid while taking Hydrocortisone Acetate Suppositories?

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication.

Do not receive a "live" vaccine while you are being treated with Hydrocortisone Acetate Suppositories. Vaccines may not work as well while you are taking a steroid.

Avoid drinking alcohol while you are taking Hydrocortisone Acetate Suppositories.

Hydrocortisone Acetate Suppositories warnings

infoWarnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
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(Systemic use): Sodium bisulfite may cause allergic – type reactions including an anaphylactic symptoms. Systemic corticosteroids should be used with great caution in the presence of heart failure, recent MI, hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, hepatic failure, osteoporosis, peptic ulceration, psychoses or severe affective disorders, and renal impairment, growth retardation in children, live vaccines should not be give to patients receiving high-dose systemic corticosteroid therapy nor for atleast 3 months afterwards. killed vaccines or toxoids may be given although the response may be attenuated.

During prolonged courses, sodium intake may need to reduced and calcium and potassium supplements may be necessary. Rapid intravenous injection of massive doses of corticosteroids may sometimes cause cardiovascular colapse and injections should therefore be given slowly or by infusion.(Topical use): Before using Hydrocortisone Acetate Suppositories,the patient has to tell the doctor or pharmacist if he is allergic to it; or to other corticosteroids (e.g., prednisone, triamcinolone); or if the patient have any other allergies. If the patient have itching of the outer female genitals with vaginal discharge, she have to consult the doctor before using this product. During pregnancy, this medication should be used only when clearly needed.

What should I discuss with my healthcare provider before taking Hydrocortisone Acetate Suppositories?

Some medical conditions may interact with Hydrocortisone Acetate Suppositories foam. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a parasitic, bacterial, fungal, or viral infection; diabetes; diarrhea; swelling of the esophagus; stomach problems; blockage or the intestine or other intestinal problems; measles; tuberculosis (TB); a positive TB skin test; chicken pox; shingles; herpes infection of the eye; ulcers; kidney problems; high blood pressure; thyroid problems; or you have received a recent vaccination
  • if you have a history of heart failure or heart attack

Some MEDICINES MAY INTERACT with Hydrocortisone Acetate Suppositories foam. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, cholestyramine, colestipol, fluconazole, hydantoins (eg, phenytoin), lithium, rifampin, or thioamines (eg, propylthiouracil) because they may decrease Hydrocortisone Acetate Suppositories foam's effectiveness
  • Aprepitant, clarithromycin, estrogens (eg, estradiol), macrolide immunosuppressants (eg, tacrolimus), nefazodone, or steroidal contraceptives (eg, birth control pills) because side effects such as adrenal gland or central nervous system problems may occur
  • Anticholinesterases (eg, pyridostigmine), anticoagulants (eg, warfarin), live vaccines, macrolide immunosuppressants (eg, tacrolimus), nondepolarizing muscle relaxants (eg, vecuronium), ritodrine, or theophylline because their actions and the risk of their side effects may be increased by Hydrocortisone Acetate Suppositories foam
  • Anticholinesterases (eg, pyridostigmine), anticoagulants (eg, warfarin), interleukin-2, mifepristone, or nondepolarizing muscle relaxants (eg, vecuronium) because their effectiveness may be decreased by Hydrocortisone Acetate Suppositories foam

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hydrocortisone Acetate Suppositories foam may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Hydrocortisone Acetate Suppositories precautions

infoCertain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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Before using Hydrocortisone Acetate Suppositories, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., prednisone, triamcinolone); or if you have any other allergies. This product may contain inactive ingredients (such as sulfites), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Do not use if there is an infection or sore in the area to be treated. Skin infections can become worse when this medication is used. Notify your doctor promptly if redness, swelling, or irritation does not improve.

Children may be more sensitive to the effects of too much corticosteroid medication. Consult your doctor for more details.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk when applied to the skin. Similar medications pass into breast milk when taken by mouth. Consult your doctor before breast-feeding.

What happens if I miss a dose of Hydrocortisone Acetate Suppositories?

infoWhen you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.

Since this medication is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.



References

  1. DailyMed. "CIPROFLOXACIN HYDROCHLORIDE; HYDROCORTISONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DrugBank. "hydrocortisone". http://www.drugbank.ca/drugs/DB00741 (accessed September 17, 2018).
  3. MeSH. "Anti-Inflammatory Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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