Hydrocortisone Acetate Pregnancy

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Pregnancy of Hydrocortisone Acetate in details

Pregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.
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Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Hydrocortisone Acetate breastfeeding

When a drug is taken when the patient is breast feeding, a part of the drug is secreted in her breast milk and is passed to the baby. The dosage of the medicine to mother and baby are different, and many drugs actions are side effects when you take them without a disease, and what if you the baby takes them without a disease? What if the drug is contraindicated in newborns, infants or children? So, breastfeeding is a very alarming situation when the mother is on medications. Ask your Physician or Pediatrician about the effect of the drug on the baby and how much is excreted in breast milk and if it harms the baby!

There are no data on the excretion of Hydrocortisone Acetate into human milk. Some corticosteroids are excreted into human milk in small amounts. The manufacturer recommends against the use of pharmacologic doses of Hydrocortisone Acetate by nursing women.

See references

References for pregnancy information

  1. Zuspan FR, Cordero L, Semchyshyn S "Effects of Hydrocortisone Acetate on lecithin-sphingomyelin ratio." Am J Obstet Gynecol 128 (1977): 571-4
  2. "Product Information. Hydrocortone (Hydrocortisone Acetate)." Merck & Co, Inc, West Point, PA.
  3. Houlihan CM, Knuppel RA, Vintzileos AM, Guo JZ, Hahn DW "The effect of specific hormones on fibrinolysis in pregnancy." Am J Obstet Gynecol 175 (1996): 168-72
  4. Wilson EA, Jawad MJ "Stimulation of human chorionic gonadotropin secretion by glucocorticoids." Am J Obstet Gynecol 142 (1982): 344-9
  5. Whitt GG, Buster JE, Killam AP, Scragg WH "A comparison of two glucocorticoid regimens for acceleration of fetal lung maturation in premature labor." Am J Obstet Gynecol 124 (1976): 479-82
  6. Tan SL, Balen A, el Hussein E, Campbell S, Jacobs HS "The administration of glucocorticoids for the prevention of ovarian hyperstimulation syndrome in in vitro fertilization: a prospectiv randomized study." Fertil Steril 58 (1992): 378-83

References for breastfeeding information

  1. "Product Information. Hydrocortone (Hydrocortisone Acetate)." Merck & Co, Inc, West Point, PA.


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References

  1. DailyMed. "CIPROFLOXACIN HYDROCHLORIDE; HYDROCORTISONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubMed Health. "Vytone: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
  3. Human Metabolome Database (HMDB). "Hydrocortisone: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).

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