Hydrocortisone Pregnancy

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Pregnancy of Hydrocortisone in details

infoPregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.
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Hydrocortisone has not been assigned to an FDA pregnancy category. Animal studies involving corticosteroids have revealed evidence of an increased incidence of cleft palate in offspring. There are no controlled data in human pregnancy, however, corticosteroids have been used during human pregnancy without evidence of teratogenicity. Hydrocortisone should be given during pregnancy only when benefit outweighs risk.

Hydrocortisone breastfeeding

infoWhen a drug is taken when the patient is breast feeding, a part of the drug is secreted in her breast milk and is passed to the baby. The dosage of the medicine to mother and baby are different, and many drugs actions are side effects when you take them without a disease, and what if you the baby takes them without a disease? What if the drug is contraindicated in newborns, infants or children? So, breastfeeding is a very alarming situation when the mother is on medications. Ask your Physician or Pediatrician about the effect of the drug on the baby and how much is excreted in breast milk and if it harms the baby!

There are no data on the excretion of hydrocortisone into human milk. Some corticosteroids are excreted into human milk in small amounts. The manufacturer recommends against the use of pharmacologic doses of hydrocortisone by nursing women.

References

  1. Human Metabolome Database (HMDB). "Hydrocortisone: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB00148... (accessed September 18, 2017).
  2. FDA Pharm Classes. "FDA Pharmacological Classification: FDA published a final rule that amended the requirements for the content and format of approved labeling (prescribing information) for human prescription drug and biological products in January 2006.". https://www.fda.gov/ForIndustry/DataStan... (accessed September 18, 2017).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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