Hydrocortone Uses

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What is Hydrocortone?

Hydrocortone valerate topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. Hydrocortone valerate is a corticosteroid (cortisone-like medicine or steroid).

Hydrocortone valerate is available only with your doctor's prescription.

Hydrocortone indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.


Replacement therapy in adrenocortical insufficiency

Adult: 20-30 mg daily in 2 divided doses.

Child: 400-800 mcg/kg/day, in 2-3 divided doses.


As supplement in adrenal insufficiency during minor surgery under general anaesthesia

Adult: In patients taking >10 mg of prednisolone or its equivalent by mouth daily. 25-50 mg at induction. Resume with usual oral corticosteroid after surgery.


As supplement in adrenal insufficiency during moderate or major surgery

Adult: In patients taking >10 mg of prednisolone or its equivalent by mouth daily. Usual oral corticosteroid dose on the morning of the surgery followed by 25-50 mg at induction, then similar doses of Hydrocortone tid for 24 hr after moderate surgery or 48-72 hr after major surgery. Resume oral therapy once injections are stopped.


Acute adrenocortical insufficiency

Adult: 100-500 mg 3-4 times/24 hr according to the severity of the condition and patient response. Fluids and electrolytes should be administered as needed to correct any metabolic disorder. Doses may also be given via IM inj but the response may be slower.

Child: <1 yr: 25 mg; 1-5 yr: 50 mg; 6-12 yr: 100 mg. Fluids and electrolytes should be administered as needed to correct any metabolic disorder. Doses may also be given via IM inj but the response may be slower.


Soft tissue inflammation

Adult: As Na phosphate or Na succinate esters: 100-200 mg as local inj.


Joint inflammations

Adult: As acetate: 5-50 mg depending on size of affected joint.


Corticosteroid-responsive dermatoses

Adult: Apply a 0.1-2.5% cream/ointment/lotion onto affected area.

How should I use Hydrocortone?

Use Hydrocortone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Hydrocortone is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Hydrocortone at home, a health care provider will teach you how to use it. Be sure you understand how to use Hydrocortone. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Hydrocortone if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Hydrocortone, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Hydrocortone.

Uses of Hydrocortone in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

It is used as a cream to treat mild to moderate inflammatory skin disorders such as mild to moderate eczema (itchy skin rash)contact dermatitis (e.g. after contact with certain plants, cosmetics, irritants like detergents), insect bite reactions.

Orally it is used to reduce pain, swelling and inflammation and to reduce the body's immune response. In general this drug is used to treat hormonal conditions when the body does not produce enough of its own steroids, and to treat a range of immune and allergic conditions. Hydrocortone is used as an injection for treating various conditions such as severe allergic reactions, arthritis, blood diseases, breathing problems, certain cancers, eye diseases, intestinal disorders, and skin diseases. The injectable form of Hydrocortone is used when a similar drug cannot be taken by mouth or when a very fast treatment is needed, especially in patients with severe medical conditions. This drug may also be used with other medications as a replacement for certain hormones.

Hydrocortone description


Hydrocortone is the most well-known of the natural metabolic intermediary of cortisols. Cortisol is corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which are a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by CRH. It increases blood pressure and blood sugar, and reduces immune responses. Various synthetic forms of cortisol are used to treat a variety of different illnesses. When first introduced as a treatment for rheumatoid arthritis, Hydrocortone was referred to as Compound E.

Active ingredient matches for Hydrocortone:

Hydrocortisone in Austria, Ireland, Japan, Portugal, Switzerland, United States.

Hydrocortisone Acetate

Unit description / dosage (Manufacturer)Price, USD
Injectable; Injection; Hydrocortisone Sodium Phosphate 25 mg / ml
Injectable; Injection; Hydrocortisone Sodium Phosphate 50 mg / ml
Ointment; Ophthalmic, Otic; Hydrocortisone Sodium Phosphate 1.5%
Tablet; Oral; Hydrocortisone Sodium Phosphate 10 mg
Tablet; Oral; Hydrocortisone Sodium Phosphate 20 mg
Tablets; Oral; Hydrocortisone Sodium Phosphate 10 mg
Tablets; Oral; Hydrocortisone Sodium Phosphate 20 mg

List of Hydrocortone substitutes (brand and generic names):

Ointment; Topical; Hydrocortisone Acetate 1% (Dermapharm)
Ointment; Topical; Hydrocortisone 1% (Dermapharm)
Cream; Topical; Hydrocortisone 0.5% (Karrer)
Cream; Topical; Hydrocortisone (Galen)
Lotion; Topical; Hydrocortisone (Galen)
Ointment; Topical; Hydrocortisone (Galen)
Solution; Topical; Hydrocortisone (Galen)
HYDROLIN 100MG INJECTION 1 vial / 1 injection each (Hetero Drugs Ltd)$ 0.66
Hydroskin cream 1 g/100g (Rugby)
Hydroskin lotion 1 g/100mL (Rugby)
Cream; Topical; Hydrocortisone 0.5% (Christo)
Hydrosone 1 % x 15 g (Christo)
Hydrosone 1 % x 450 g (Christo)
Cream; Topical; Hydrocortisone 1% (Christo)
Hydrotopic / Vial 100 mg x 10's (Vendiz)$ 26.44
Hydrotopic 250 mg x 10's (Vendiz)$ 51.33
Hydrotopic Cream 1 % x 5 g$ 3.73
Hydrotopic Cream 1 % x 500 g$ 64.71
Hys NA Injection (Speciality Meditech Pvt Ltd)$ 0.68
HYS 100 1GM INJECTION 1 vial / 1 injection each (Speciality Meditech Pvt Ltd)$ 0.68


  1. DailyMed. "CIPROFLOXACIN HYDROCHLORIDE; HYDROCORTISONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailymed/se... (accessed September 18, 2017).
  2. Wikipedia. "cortisol: Link to the compound information in Wikipedia.". https://en.wikipedia.org/wiki/Cortisol (accessed September 18, 2017).
  3. PubChem. "hydrocortisone". https://pubchem.ncbi.nlm.nih.gov/compoun... (accessed September 18, 2017).
  4. FDA Orange Book. "Patent:6514980: The publication, Approved Drug Products with Therapeutic Equivalence Evaluations (the List, commonly known as the Orange Book), identifies drug products approved on the basis of safety and effectiveness by the Food and Drug Administration (FDA) under the Federal Food, Drug, and Cosmetic Act (the Act).". https://www.fda.gov/Drugs/InformationOnD... (accessed September 18, 2017).


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