Hydroquinone Actions

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Actions of Hydroquinone in details

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Hydroquinone bleaches the skin by reducing the accumulation of skin pigment called melanin that causes darkening of skin. It interferes with the synthesis of melanin and hampers important processes within cells that produce melanin (melanocytes). The bleaching effect of Hydroquinone is reversible (reversible depigmentation).

Hydroquinone administration

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Hydroquinone topical is for external use only.

Wash your hands before and after applying this medication, unless you are treating a skin area on your hand.

Apply the medication to clean, dry skin. Apply just enough medication to cover the affected area. Avoid applying to the unaffected surrounding skin. Rub in the medication gently and completely.

Avoid getting this medication on your lips or inside your nose or mouth. Hydroquinone may cause numbness of these areas. If the medication does get on any of these areas, rinse with water.

It is important to use Hydroquinone topical regularly to get the most benefit.

Store Hydroquinone topical at room temperature away from moisture and heat.

Hydroquinone pharmacology

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Topical application of Hydroquinone produces a reversible depigmentation of the skin by inhibition of the enzymatic Hydroquinone. oxidation of tyrosine to 3, 4-dihydroxyphenylalanine (dopa) 1 and suppression of other melanocyte metabolic processes. Exposure to sunlight or ultraviolet light will cause regimentation of the bleached areas.

References

  1. DailyMed. "FLUOCINOLONE ACETONIDE; HYDROQUINONE; TRETINOIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. NCIt. "Hydroquinone: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
  3. EPA Air Toxics. "Hydroquinone: EPA Health Effects Notebook for Hazardous Air Pollutants". https://www.epa.gov/sites/production... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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