Hypen SR belongs to the group of medicines known as diuretics. It is commonly used to treat high blood pressure (hypertension).
High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Hypen SR is also used to help reduce the amount of water in the body by increasing the flow of urine.
Hypen SR is available only with your doctor's prescription.
Hypen SR indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Hypen SR (Hypen SR) is indicated for the treatment of hypertension, alone or in combination with other antihypertensive drugs.
Hypen SR (Hypen SR) is also indicated for the treatment of salt and fluid retention associated with congestive heart failure.
Usage in Pregnancy
The routine use of diuretics in an otherwise healthy woman is inappropriate and exposes mother and fetus to unnecessary hazard.
Diuretics do not prevent development of toxemia of pregnancy, and there is no satisfactory evidence that they are useful in the treatment of developed toxemia.
Edema during pregnancy may arise from pathological causes or from the physiologic and mechanical consequences of pregnancy. Hypen SR is indicated in pregnancy when edema is due to pathologic causes, just as it is in the absence of pregnancy (however, see PRECAUTIONS below). Dependent edema in pregnancy, resulting from restriction of venous return by the expanded uterus, is properly treated through elevation of the lower extremities and use of support hose; use of diuretics to lower intravascular volume in this case is illogical and unnecessary. There is hypervolemia during normal pregnancy which is not harmful to either the fetus or the mother (in the absence of cardiovascular disease), but which is associated with edema, including generalized edema in the majority of pregnant women. If this edema produces discomfort, increased recumbency will often provide relief. In rare instances, this edema may cause extreme discomfort which is not relieved by rest. In these cases, a short course of diuretics may provide relief and may be appropriate.
How should I use Hypen SR?
Use Hypen SR as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Hypen SR by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
Hypen SR may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
If you miss a dose of Hypen SR and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Hypen SR.
Uses of Hypen SR in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Use: Labeled Indications
Heart failure: Treatment of edema in heart failure
Hypertension: Management of mild to moderate hypertension
Guideline recommendations: The 2017 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults recommends if monotherapy is warranted, in the absence of comorbidities (eg, cerebrovascular disease, chronic kidney disease, diabetes, heart failure, ischemic heart disease, etc), that thiazide-like diuretics or dihydropyridine calcium channel blockers may be preferred options due to improved cardiovascular endpoints (eg, prevention of heart failure and stroke). ACE inhibitors and ARBs are also acceptable for monotherapy. Combination therapy may be required to achieve blood pressure goals and is initially preferred in patients at high risk (stage 2 hypertension or atherosclerotic cardiovascular disease [ASCVD] risk ≥10%) (ACC/AHA [Whelton 2017]).
Off Label Uses
Calcium nephrolithiasis
Data from a prospective, randomized, study supports the use of Hypen SR for the prevention of recurrent calcium nephrolithiasis. Additional trials may be necessary to further define the role of Hypen SR in the treatment of this condition.
Based on the American Urologic Association (AUA) guidelines for the medical management of kidney stones, Hypen SR is effective and recommended for the prevention of recurrent calcium stones in patients with high or relatively high urine calcium concentrations.
Hypen SR description
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Hypen SR also contains the following excipients: Tablet: Lactose monohydrate 124.5 mg, anhydrous colloidal silica, hypromellose, magnesium stearate, povidone. Film-coating: Glycerol, hypromellose, macrogol 6000, magnesium stearate, titanium dioxide.
Hypen SR dosage
Hypen SR Dosage
Generic name: Hypen SR
Dosage form: Tablets
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Hypertension
The adult starting Hypen SR dose for hypertension is 1.25 mg as a single daily dose taken in the morning. If the response to 1.25 mg is not satisfactory after four weeks, the daily dose may be increased to 2.5 mg taken once daily. If the response to 2.5 mg is not satisfactory after four weeks, the daily dose may be increased to 5.0 mg taken once daily, but adding another antihypertensive should be considered.
Edema of Congestive Heart Failure
The adult starting Hypen SR dose for edema of congestive heart failure is 2.5 mg as a single daily dose taken in the morning. If the response to 2.5 mg is not satisfactory after one week, the daily dose may be increased to 5.0 mg taken once daily.
If the antihypertensive response to Hypen SR is insufficient, Hypen SR may be combined with other antihypertensive drugs, with careful monitoring of blood pressure. It is recommended that the usual dose of other agents be reduced by 50% during initial combination therapy. As the blood pressure response becomes evident, further dosage adjustments may be necessary.
In general, doses of 5.0 mg and larger have not appeared to provide additional effects on blood pressure or heart failure, but are associated with a greater degree of hypokalemia. There is minimal clinical trial experience in patients with doses greater than 5.0 mg once a day.
Hypen SR (Hypen SR) may add to or potentiate the action of other antihypertensive drugs. In limited controlled trials that compared the effect of Hypen SR combined with other antihypertensive drugs with the effect of the other drugs administered alone, there was no notable change in the nature or frequency of adverse reactions associated with the combined therapy.
Lithium
Post-Sympathectomy Patient
The antihypertensive effect of the drug may be enhanced in the post-sympathectomized patient.
Norepinephrine
Hypen SR, like the thiazides, may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use.
In addition to its needed effects, some unwanted effects may be caused by Hypen SR (the active ingredient contained in Hypen SR). In the event that any of these side effects do occur, they may require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Hypen SR, check with your doctor or nurse as soon as possible:
Signs and symptoms of an imbalance of water or potassium in the body
Dryness of mouth
increased thirst
irregular heartbeat
mood or mental changes
muscle cramps or pain
nausea or vomiting
unusual tiredness or weakness
weak pulse
Rare
Skin rash, itching, or hives
Minor Side Effects
Some of the side effects that can occur with Hypen SR may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Less common or rare:
Diarrhea
dizziness or lightheadedness, especially when getting up from a lying or sitting position
Hypersensitivity to Hypen SR or any component of the formulation or sulfonamide-derived drugs; anuria
Note: Although the FDA approved product labeling states this medication is contraindicated with other sulfonamide-containing drug classes, the scientific basis of this statement has been challenged. See “Warnings/Precautions” for more detail.
Canadian labeling: Additional contraindications (not in US labeling): Severe renal failure (CrCl <30 mL/minute); hepatic encephalopathy; severe hepatic impairment; hypokalemia; concomitant use with antiarrhythmic agents causing torsade de pointes; pregnancy; breast-feeding; hereditary problems of galactose intolerance, glucose-galactose malabsorption, or Lapp lactase deficiency
DailyMed. "INDAPAMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
The results of a survey conducted on ndrugs.com for Hypen SR are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Hypen SR. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
User reports
2 consumers reported useful
Was the Hypen SR drug useful in terms of decreasing the symptom or the disease? According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users
%
Useful
2
100.0%
Consumer reported price estimates
No survey data has been collected yet
1 consumer reported time for results
To what extent do I have to use Hypen SR before I begin to see changes in my health conditions? As part of the reports released by ndrugs.com website users, it takes > 3 month and a few days before you notice an improvement in your health conditions. Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Hypen SR. To get the time effectiveness of using Hypen SR drug by other patients, please click here.
Users
%
> 3 month
1
100.0%
4 consumers reported age
Users
%
30-45
1
25.0%
1-5
1
25.0%
46-60
1
25.0%
16-29
1
25.0%
Consumer reviews
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