What is Intabion DPS?
Intabion DPS nasal spray contains Cyanocobalamin, a man-made form of Intabion DPS. Intabion DPS is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.
Intabion DPS nasal spray is used to treat Intabion DPS deficiency in people with pernicious anemia and other conditions.
Intabion DPS nasal spray is usually given after treatment with an injection form of this medicine.
Intabion DPS may also be used for purposes not listed in this medication guide.
Intabion DPS indications
Intabion DPS Maintenance Therapy
Intabion DPS is indicated for maintenance of Intabion DPS concentrations after normalization with intramuscular Intabion DPS therapy in patients with Intabion DPS deficiency who have no nervous system involvement.
Important Limitations of Use
Intabion DPS has not been evaluated for the treatment of newly diagnosed Intabion DPS deficiency.
Intabion DPS is not suitable for use in the Intabion DPS absorption test (Schilling Test).
The effectiveness of Intabion DPS in patients with nasal pathology (e.g., nasal congestion, allergic rhinitis, upper respiratory infections) has not been determined. Treatment with Intabion DPS should be deferred until nasal symptoms have subsided.
How should I use Intabion DPS?
Use Intabion DPS as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Intabion DPS. Talk to your pharmacist if you have questions about this information.
- Intabion DPS is used in the nose.
- Follow the directions provided by your doctor or other health care provider. If you are unsure how to use Intabion DPS, contact your doctor or other health care provider.
- Do not use Intabion DPS within 1 hour before or after eating or drinking hot foods or liquids.
- Prime the pump before the first use. Place the nozzle between the first and second finger with the thumb on the bottom. Point the nozzle away from yourself and others. Pump the unit firmly and quickly until the medicine sprays out, then spray two more times.
- Re-prime the pump before each dose. Point the nozzle away from yourself and others, then spray once.
- Use Intabion DPS in only 1 nostril each week.
- To use Intabion DPS, sit down and tilt your head back slightly. Place the tip of the spray container into the nose. Using a finger from your other hand, press against the opposite nostril to close it off. Breath gently through the open nostril and spray a dose of medicine from the container. After using the medicine, rinse the tip of the spray unit in hot water and dry with a clean tissue to prevent contamination.
- Intabion DPS is usually used 1 time per week. Do not use it more often than 1 time per week without checking with your doctor.
- This bottle contains 8 doses. Do not continue to use this bottle after 8 doses have been used. It may not give the correct amount of medicine.
- Continue to use Intabion DPS even if you feel well. Do not miss any doses.
- If you miss a dose of Intabion DPS, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Intabion DPS.
Uses of Intabion DPS in details
How to use Intabion DPS nasal
Intabion DPS description
Intabion DPS (commonly known as Intabion DPS) is the most chemically complex of all the vitamins. Intabion DPS's structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Intabion DPS cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of Intabion DPS are bacteria and archaea. Higher plants do not concentrate Intabion DPS from the soil and so are a poor source of the substance as compared with animal tissues. Intabion DPS is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products. [HMDB]
Intabion DPS dosage
Intabion DPS Dosage
Generic name: Intabion DPS 25ug in 0.1mL
Dosage form: nasal spray, metered
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Recommended Dose
The recommended initial dose of Intabion DPS is one spray in each nostril once daily (25 mcg per nostril, total daily dose 50 mcg). The dose should be increased to one spray in each nostril twice daily (total daily dose 100 mcg) for patients with an inadequate response to once daily dosing.
The dosing of Intabion DPS and other intranasal medications should be separated by several hours, and these patients should have more frequent monitoring of Intabion DPS concentrations because of the potential for erratic absorption.
Priming (Activation) of Pump
The pump must be primed before the bottle is used for the first time. To prime the pump, place the nozzle between the first and second finger with the thumb on the bottom of the bottle. Pump the unit firmly and quickly then repeat this priming an additional 6 times for a total of 7 priming sprays. Now the nasal spray is ready for first-time use. If 5 or more days elapse since last use, the pump must be re-primed with two re-priming sprays.
Additional instructions are provided in the patient instruction sheet.
More about Intabion DPS (Intabion DPS)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- 1 Review - Add your own review/rating
Consumer resources
- Intabion DPS
- Intabion DPS (Advanced Reading)
- Other brands: Intabion DPS, Nascobal, B-12, Eligen B12, More (8) »
Professional resources
- Intabion DPS (FDA)
Related treatment guides
- B12 Nutritional Deficiency
- Pernicious Anemia
- Schilling Test
- Intabion DPS Deficiency
Intabion DPS interactions
See also:
What other drugs will affect Intabion DPS?
In an application of Intabion DPS Atlantic Laboratories with hormonal contraceptives for oral administration may decrease the concentration of Intabion DPS in plasma.
In an application with anticonvulsant drugs decreased Intabion DPS absorption from the gut.
In an Intabion DPS Atlantic Laboratories application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased Intabion DPS absorption from the gut.
Intabion DPS may exacerbate allergic reactions caused by thiamine.
When parenteral application of chloramphenicol may decrease the hematopoietic effects of Intabion DPS with anemia.
Intabion DPS side effects
See also:
What are the possible side effects of Intabion DPS?
Applies to Intabion DPS: intramuscular solution
Other dosage forms:
- nasal gel/jelly, nasal spray
As well as its needed effects, Intabion DPS (the active ingredient contained in Intabion DPS) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking Intabion DPS, check with your doctor or nurse immediately:
Incidence not known:
- Abdominal or stomach pain
- bleeding from the gums or nose
- blue lips and fingernails
- chest pain
- cough
- coughing that sometimes produces a pink frothy sputum
- decreased urine output
- difficult, fast, noisy breathing, sometimes with wheezing
- difficulty with swallowing
- dilated neck veins
- dizziness
- extreme fatigue
- eye pain
- fast heartbeat
- headache
- hives, itching, or skin rash
- increased sweating
- irregular breathing
- irregular heartbeat
- pale skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- ringing in the ears
- swelling of the face, fingers, feet, or lower legs
- tightness in the chest
- unusual tiredness or weakness
- weight gain
Minor Side Effects
Some Intabion DPS side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
Incidence not known:
- Diarrhea
- skin rash with a general disease
Intabion DPS contraindications
See also:
What is the most important information I should know about Intabion DPS?
You should not use this medication if you are allergic to cobalt, or if you have Leber's disease. Intabion DPS can lead to optic nerve damage (and possibly blindness) in people with Leber's disease.
To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life. Not using the medication can lead to irreversible nerve damage in your spinal cord.
Pernicious anemia is also treated with folic acid to help maintain red blood cells. However, folic acid will not treat Intabion DPS deficiency and will not prevent possible damage to the spinal cord. Take all of your medications as directed.
Your dose needs may change if you become pregnant, if you breast-feed, or if you eat a vegetarian diet. Tell your doctor about any changes in your diet or medical condition.
Active ingredient matches for Intabion DPS:
Cyanocobalamin in India.
D-panthenol/L-lysine/niacinamide/pyridoxine/riboflavin/thiamine in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| Intabion DPS L-lysine 50 mg, niacinamide 15mg, D-panthenol 3 mg, riboflavin 2.5 mg, thiamine 2mg, pyridoxine 0.75 mg, cyanocobalamin 2 mcg/1 mL. DPS / 15ml | $ 0.46 |
| INTABION DPS oral drops 15ml (Intas) | $ 0.46 |
List of Intabion DPS substitutes (brand and generic names): | |
| Intabion Tab (India) | |
| INTABION TAB tab 10's (Intas) | $ 0.17 |
| Intravit 12 (Netherlands, South Africa, United Kingdom) | |
| Intravit B12 (Poland) | |
| Iro-Life SYP (India) | |
| Iro-Life SYP Carbonyl iron 50 mg, folicacid, Cyanocobalamin. SYR / 200ml (Lifeline) | $ 0.87 |
| 200ml (Lifeline) | $ 0.87 |
| IRO-LIFE SYP syr 200ml (Lifeline) | $ 0.87 |
| Ironifol (India) | |
| Ironifol Iron / III hydroxidepolymaltose complex 50 mg, Cyanocobalamin 5 mcg, Folicacid 500 mcg/5 mL. LIQD / 200ml (Radicura Pharmaceutical Pvt. Ltd.) | $ 0.78 |
| 200ml (Radicura Pharmaceutical Pvt. Ltd.) | $ 0.78 |
| Ironifol 100+1.5 Capsule (Radicura Pharmaceutical Pvt. Ltd.) | $ 0.05 |
| Ironifol 200 ml Syrup (Radicura Pharmaceutical Pvt. Ltd.) | $ 0.02 |
| IRONIFOL oral liqd 200ml (Radicura Pharmaceutical Pvt. Ltd.) | $ 0.78 |
| Iroplex Tab (India) | |
| Iroplex Tab Ferrous fumarate 400 mg, Folicacid 1.5 mg, cyanocobalamin 15mcg, zinc sulphate 61.8 mg. TAB / 100 (Acme Pharma) | $ 4.82 |
| 100's (Acme Pharma) | $ 4.82 |
| IROPLEX TAB tab 10's (Acme Pharma) | $ 0.48 |
| Iroplex-SR (India) | |
| Iroplex-SR Ferrous fumarate 200 mg, Folicacid 1500 mcg, Cyanocobalamin10 mcg, zinc sulphate 61.8 mg. CAP / 100 (Acme Pharma) | $ 4.82 |
| 100's (Acme Pharma) | $ 4.82 |
| IROPLEX-SR cap 10's (Acme Pharma) | $ 0.48 |
| Irorange (India) | |
| Irorange Ferric ammonium citrate 160mg, Folic acid 0.5 mg, cyanocobalamin 7.5 mcg, sorbitol 10 % w/v/15 mL. SYR / 200ml (Daniel) | $ 0.77 |
| 200ml (Daniel) | $ 0.77 |
| IRORANGE syr 200ml (Daniel) | $ 0.77 |
| Irossgold Susp (India) | |
| Irossgold Susp Elemental iron / carbonyl iron25 mg, Elemental zinc 11 mg, cyanocobalamin 6 mcg, folicacid 500 mg. SUSP / 200ml (Yash Pharma) | $ 0.54 |
| IROSSGOLD SUSP oral susp 200ml (Yash Pharma) | $ 0.54 |
| Irossgold Suspension (India) | |
| Irossgold Suspension Elemental iron / carbonyl iron25 mg, Elemental zinc 11 mg, cyanocobalamin 6 mcg, folicacid 500 mg. SUSP / 200ml | $ 0.54 |
| 200ml | $ 0.54 |
| Irotone (India) | |
| Irotone Ferric ammonium citrate 160mg, Folic acid 0.5 mg, cyanocobalamin 7.5 mg SYR / 200ml (Orison Pharmaceuticals) | |
| 200ml (Orison Pharmaceuticals) | |
| Irotone 200 ml Syrup (Orison Pharmaceuticals) | $ 0.02 |
| IROTONE syr 200ml (Orison Pharmaceuticals) | |
| Irum SYR (India) | |
| Irum SYR Elemental iron 50 mg, zincsulphate monohydrate 11 mg, folic acid 500 mcg, cyanocobalamin 5 mcg. SYR / 200ml (Daffohils) | |
| 200ml (Daffohils) | |
| IRUM SYR syr 200ml (Daffohils) | |
| Iryl-C Susp (India) | |
| Iryl-C Susp Elemental iron 25 mg, folicacid 500 mcg, cyanocobalamin 6mcg, zinc sulphate monohydrate11 mg/5 mL. SUSP / 200ml (Health Care) | $ 0.82 |
| 200ml (Health Care) | $ 0.82 |
| IRYL-C SUSP oral susp 200ml (Health Care) | $ 0.82 |
| Isopto B12 (Spain) | |
| Izeal (India) | |
| Izeal Lutein 6 mg, beta carotene4000 IU, Folic acid 2.5 mg, Cyanocobalamin 500 mcg, Zincsulphate monohydrate 15 mg, Copper sulphate pentahydrate 2mg, Manganese sulphatemonohydrate 1.5 mg, Seleniumdioxide 75 mcg, Pyridoxinehydrochloride 50 mg, Chromiumpicoli (FDC (Lumina)) | $ 0.78 |
| 10's (FDC (Lumina)) | $ 0.78 |
| Izeal Lutein 6 mg, beta carotene4000 IU, Folic acid 2.5 mg, Cyanocobalamin 500 mcg, Zincsulphate monohydrate 15 mg, Copper sulphate pentahydrate 2mg, Manganese sulphatemonohydrate 1.5 mg, Seleniumdioxide 75 mcg, Pyridoxinehydrochloride 50 mg, Chromiumpicoli (FDC (Lumina)) | $ 0.78 |
| Izeal Lutein 6 mg, beta carotene4000 IU, Folic acid 2.5 mg, Cyanocobalamin 500 mcg, Zincsulphate monohydrate 15 mg, Copper sulphate pentahydrate 2mg, Manganese sulphatemonohydrate 1.5 mg, Seleniumdioxide 75 mcg, Pyridoxinehydrochloride 50 mg, Chromiumpicoli (FDC (Lumina)) | $ 0.78 |
| Izeal Lutein 6 mg, beta carotene4000 IU, folic acid 2.5 mg, cyanocobalamin 500 mcg, zincsulphate monohydrate 15 mg, copper sulphate pentahydrate 2mg, manganese sulphatemonohydrate 1.5 mg, seleniumdioxide 75 mcg, pyridoxinehydrochloride 50 mg, chromiumpicoli (FDC (Lumina)) | $ 0.78 |
| Izeal Lutein 6 mg, beta carotene4000 IU, Folic acid 2.5 mg, Cyanocobalamin 500 mcg, Zincsulphate monohydrate 15 mg, Copper sulphate pentahydrate 2mg, Manganese sulphatemonohydrate 1.5 mg, Seleniumdioxide 75 mcg, Pyridoxinehydrochloride 50 mg, Chromiumpicoli (FDC (Lumina)) | $ 0.78 |
| Izeal Lutein 6 mg, beta carotene4000 IU, folic acid 2.5 mg, cyanocobalamin 500 mcg, zincsulphate monohydrate 15 mg, copper sulphate pentahydrate 2mg, manganese sulphatemonohydrate 1.5 mg, seleniumdioxide 75 mcg, pyridoxinehydrochloride 50 mg, chromiumpicoli (FDC (Lumina)) | $ 0.78 |
See 1623 substitutes for Intabion DPS | |
References
- DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "L-lysine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Intabion DPS are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Intabion DPS. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
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Information checked by Dr. Sachin Kumar, MD Pharmacology
