Iodine 2% Actions

What is the dose of your medication?

Actions of Iodine 2% in details

The action of the drug on the human body is called Pharmacodynamics in Medical terminology. To produce its effect and to change the pathological process that is happening the body and to reduce the symptom or cure the disease, the medicine has to function in a specific way. The changes it does to the body at cellular level gives the desired result of treating a disease. Drugs act by stimulating or inhibiting a receptor or an enzyme or a protein most of the times. Medications are produced in such a way that the ingredients target the specific site and bring about chemical changes in the body that can stop or reverse the chemical reaction which is causing the disease.


Oral Iodine 2% (converted to iodide) is essential for synthesis of thyroid hormones.

Topical Iodine 2% acts as a local irritant and as a germicide active against gram-positive and gram-negative bacteria, fungi, trichomonas, cysts, viruses and some spores.


Absorption: Slightly absorbed (topical); transported and concentrated in the thyroid gland (oral).


Oral: Crosses the placenta; enters breast milk.


Oral: Mainly via urine; via faeces, saliva and sweat (small amounts).

How should I take Iodine 2%?

Use Iodine 2% only as directed.

Iodine 2% is for external use only. Do not swallow it.

Keep Iodine 2% away from the eyes because it may cause irritation. If you should accidentally get some in your eyes, wash it away with water immediately.

Do not use topical Iodine 2% on deep, puncture wounds, animal bites, or serious burns. To do so may increase the chance of side effects.

Do not cover the wound to which you have applied topical Iodine 2% with a tight dressing or bandage since this may increase the chance of side effects.


The dose of Iodine 2% will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of Iodine 2%. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

To help clear up your infection completely, it is very important that you keep using topical Iodine 2% for the full time of treatment. Do not miss any doses.

Missed Dose

If you miss a dose of Iodine 2%, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Iodine 2% administration

Administration of drug is important to know because the drug absorption and action varies depending on the route and time of administration of the drug. A medicine is prescribed before meals or after meals or along with meals. The specific timing of the drug intake about food is to increase its absorption and thus its efficacy. Few work well when taken in empty stomach and few medications need to be taken 1 or 2 hrs after the meal. A drug can be in the form of a tablet, a capsule which is the oral route of administration and the same can be in IV form which is used in specific cases. Other forms of drug administration can be a suppository in anal route or an inhalation route.

Topical: Iodosorb®: Apply /" thickness to dry sterile gauze, then place prepared gauze onto clean wound. Change dressing when gel changes color from brown to yellow/gray (~3 times/week). Remove with sterile water, saline, or wound cleanser; gently blot fluid from surface leaving wound slightly moist before reapplying gel.

Iodine 2% pharmacology

Pharmacokinetics of a drug can be defined as what body does to the drug after it is taken. The therapeutic result of the medicine depends upon the Pharmacokinetics of the drug. It deals with the time taken for the drug to be absorbed, metabolized, the process and chemical reactions involved in metabolism and about the excretion of the drug. All these factors are essential to deciding on the efficacy of the drug. Based on these pharmacokinetic principles, the ingredients, the Pharmaceutical company decides dose and route of administration. The concentration of the drug at the site of action which is proportional to therapeutic result inside the body depends on various pharmacokinetic reactions that occur in the body.

Iodine 2% is required for thyroid hormone synthesis. Iodine 2% is also known to be a powerful broad spectrum germicidal agent effective against a wide range of bacteria, viruses, fungi, protozoa, and spores. Iodosorb® and Iodoflex™ contain Iodine 2% in hydrophilic beads of cadexomer which allows a slow release of Iodine 2% into the wound and absorption of fluid, bacteria, and other substances from the wound


Topical: Amount absorbed systemically depends upon concentration and characteristics of skin


Primarily trapped by the thyroid


Degraded by amylases normally present in wound fluid


Urine (>90%)



  1. NCIt. "Iodine: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". (accessed September 17, 2018).
  2. EPA DSStox. "Iodine: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". (accessed September 17, 2018).
  3. EPA Office of Pesticide Programs. "The EPA OPP Pesticide Ecotoxicity Database, updated by the Ecological Fate and Effects Division of the EPA Office of Pesticide Programs, contains all EPA reviewed ecotoxicity endpoints for pesticides registered or previously registered in the U.S. Toxicity data. ". (accessed September 17, 2018).


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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