Iron Uses

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What is Iron?

Carbonyl Iron is an Iron replacement product. You normally get Iron from the foods you eat. Iron helps your body produce red blood cells that carry oxygen through your blood to tissues and organs.

Carbonyl Iron is used to treat or prevent Iron deficiency and Iron deficiency anemia.

Carbonyl Iron may also be used for purposes not listed in this medication guide.

Iron indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Film-Coated Tablet: Treatment of Iron deficiency. Prevention of Iron deficiency during pregnancy.

Syrup: All cases of Iron deficiency and Iron deficiency anaemia.

Drops: General: Hypochromic or masked Iron deficiency anaemias. General weakness. Convalescence. Blood losses. Tropical microcytic anaemia. Anaemias due to infections. For maintenance therapy in pernicious anaemia. As an adjuvant in treating chronically ill or undernourished patients.

Women: Iron deficiency due to menstruation. During and after pregnancy and lactation. Menorrhagia.

Children: All types of hypochromic anaemias and masked Iron deficiencies. Inappetence. Retarded growth. Weakness. Unsound dietary habits. To speed up restoration of depleted Iron reserves.

How should I use Iron?

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Use Iron suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Iron suspension.

Iron description

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Each 5 mL syrup contains: Diastase (1:50) 135 mg, pepsin 50 mg, papain BPC 50 mg, vitamin B1 5 mg, vitamin B2 2 mg, vitamin B6 2 mg, vitamin B12 5 mcg, calcium pantothenate 1 mg and nicotinamide 20 mg.

Iron is a pleasantly flavoured syrup, containing digestive enzymes and vitamins of the B-complex group. Abdominal cramps, flatulence, heartburn and nausea can occur as a result of indigestion. Iron is the ideal cure to facilitate digestion and to strengthen the GIT.

Iron's balanced formulation provides an ideal supplementation that meets the demands and replenishes vitamins stores in the body.

Iron dosage

Film-Coated Tablet: Treatment of Iron Deficiency with Reduced Number of Red Blood Cells in Adults and Children over 12 Years: 1 to 3 tablets once daily or divided into separate doses for about 3 to 5 months.

After normalisation of the red blood pigment (haemoglobin) value, continue with 1 tablet once daily for several weeks. This will replenish the Iron stores.

Treatment of Iron Deficiency with Reduced Number of Red Blood Cells in Pregnancy: 2 to 3 tablets once daily or divided into separate doses.

After normalisation of the red blood pigment value, continue with 1 tablet once daily until, at least, the end of pregnancy. This will replenish the Iron stores and provide the increased amount of Iron required during pregnancy.

Treatment of Iron Deficiency with Normal Number of Red Blood Cells in Adults, Pregnancy, and Children over 12 years, and Prevention of Iron Deficiency in Pregnancy: 1 tablet once daily for 1 to 2 months.

Syrup: Adults: 5 mL 2 to 3 times daily before meals.

Children: 5 mL 1 to 2 times daily before meals.

Infants: Begin with 2.5 mL daily and gradually increase to 5 mL daily.

Drops: Adults: 20 drops 2 to 3 times daily during or after a meal.

Children: 20 drops 1 to 2 times daily during or after a meal.

Infants: Begin with 6 drops daily and gradually increase to 20 drops daily.

Iron may be mixed with fruit, vegetable juices or other liquids if desired.

Best results are obtained by adequate dosage and regular administration. It is recommended that the therapy in conformity to the degree of Iron deficiency should be continued for at least 1 to 2 months.

Administration: Take Iron during or immediately after meal.

Duration of use depends upon the degree of Iron deficiency.

Do not discontinue sooner than recommended as this may reduce the success of therapy.

Iron interactions

See also:
What other drugs will affect Iron?

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Drug interactions were not noted and were not studied in clinical studies.

Feridex I.V. (ferumoxides injectable solution) administration provides elemental Iron. In patients who are receiving supplemental Iron orally or parenterally, the dose of supplemental Iron may need to be decreased.

The effect of concomitant parenteral Iron on Feridex I.V. dosing is not known.

Laboratory Test Findings

Serum Iron levels may be above the normal range following Feridex I.V. (ferumoxides injectable solution) administration. Transient increases in serum Iron of 15–100% of baseline were observed 18 to 24 hours after Feridex I.V. (ferumoxides injectable solution) administration, and returned to normal in most patients by 7 days after administration. Increases in serum ferritin levels were seen 1 to 7 days after administration.

In a Phase 1 study in normal subjects, PTT was statistically significantly increased; however, all values were within the normal range and no subjects had a more than 40% increase from baseline. In clinical trials of patients who had baseline hematologic abnormalities associated with underlying liver disease, an effect of Feridex I.V. (ferumoxides injectable solution) on platelet or PTT was not demonstrated. In patients with low hematocrit and hemoglobin, over a period of 48 hours to 7 days after Feridex I.V. (ferumoxides injectable solution), the serum Iron, the hematocrit and hemoglobin levels increase slightly.

Iron side effects

See also:
What are the possible side effects of Iron?

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Applies to carbonyl Iron: suspension

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; darkened or green stools; diarrhea; loss of appetite; nausea; stomach cramps, pain, or upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking carbonyl Iron (the active ingredient contained in Iron)

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or tarry stools; blood or streaks of blood in the stool; fever; severe or persistent nausea, stomach pain, or vomiting; vomit that looks like blood or coffee grounds.

Iron contraindications

See also:
What is the most important information I should know about Iron?

All cases of Iron overload and disturbances in utilization of Iron.

Film-Coated Tablet: Allergy to Iron (III)-hydroxide polymaltose complex or any of the other ingredients of Iron.

An Iron overload in the body.

Disturbed use of Iron by the body.

Reduced number of red blood cells (anaemia), not caused by Iron deficiency, such as due to increased red blood cell breakdown, vitamin B12 deficiency.



Active ingredient matches for Iron:

Iron


Unit description / dosage (Manufacturer)Price, USD
Tablet, Extended Release; Oral; Iron / Ferrous Sulfate 50 mg
Tablet; Oral; Iron / Ferrous Fumarate 30 mg
Liquid; Sublingual; Iron 1 x / ml
Tablet; Oral; Iron / Ferrous HVP Chelate 9 mg
Capsule; Oral; Iron / Iron Proteinate 40 mg
Tablet, Extended Release; Oral; Iron / Ferrous Gluconate 50 mg
Tablet; Oral; Iron / Ferrous Gluconate 35 mg
Tablet; Oral; Iron / Ferrous Fumarate 18 mg
Capsule; Oral; Iron / Ferrous Fumarate 18 mg
Tablet; Oral; Iron / Ferrous HVP Chelate 25 mg
Injectable; Injection; Iron / Iron Dextran Complex 100 mg / ml
Tablet; Oral; Iron / Ferrous Gluconate 34.7 mg
Capsule; Oral; Iron / Ferrous HVP Chelate 50 mg
Iron chews 15 mg tablet chew$ 0.29
Ferrous sulfate 28 mg tablet$ 0.04
Iron capsule 40 mg (Seroyal International Inc. (Canada))

List of Iron substitutes (brand and generic names):

Suspension; Oral; Iron / Iron Amino Acid Chelate 8.55 mg / ml
Tablet; Oral; Iron / Iron Amino Acid Chelate 25 mg
Tablet; Oral; Iron Amino Acid Chelate 15 mg
Tablet; Oral; Iron / Iron HVP Chelate 37 mg
Capsule; Oral; Iron / Ferrous Ascorbate 50 mg
Tablet; Oral; Iron / Ferrous HVP Chelate 25 mg
Capsule; Oral; Iron / Ferric Citrate 30 mg
Injectable; Injection; Iron / Iron Dextran Complex 100 mg / ml
Injectable; Injection; Iron / Iron Dextran Complex 50 mg / ml
Iron dextran comp 100 mg/2 ml$ 38.08
Dexferrum 100 mg/2 ml vial$ 21.60
Dexferrum 50 mg/ml vial$ 21.60
Dexiron 50 mg/ml$ 15.66
Infufer 50 mg/ml$ 15.53
Infed 100 mg/2 ml vial$ 14.44
Tablet; Oral; Iron / Iron HVP Chelate 25 mg
Tablet; Oral; Iron / Ferrous HVP Chelate 25 mg
Ironate 200 ml Syrup (Chemo Drugs)$ 0.02
IRONATE cap 10's (Chemo Drugs)$ 0.30
Injectable; Injection; Iron / Iron Dextran Complex 100 mg / ml
Irovir Inj Injection (East African (I) Remedies Pvt Ltd)$ 0.08
Irovir 150 ml Suspension (East African (I) Remedies Pvt Ltd)$ 0.03
Irovir 15 ml Drop (East African (I) Remedies Pvt Ltd)$ 0.05
Irovir I Inj Injection (East African (I) Remedies Pvt Ltd)$ 0.15
IROZORB S 50MG INJECTION 1 vial / 5 ML injection each (Macleods Pharmaceuticals Pvt Ltd)$ 3.47
Isofer Ferric ammonium citrate 160mg, folic acid 0.5 mg, cyanocobalamin 7.5 mg. SYR / 200ml (Zenacts Pharma (Kaizen Drugs (P) Ltd))$ 1.08
200ml (Zenacts Pharma (Kaizen Drugs (P) Ltd))$ 1.08
Isofer 200 ml Syrup (Zenacts Pharma (Kaizen Drugs (P) Ltd))$ 0.03
ISOFER 100MG INJECTION 1 vial / 5 ML injection each (Zenacts Pharma (Kaizen Drugs (P) Ltd))$ 46.03
ISOFER syr 200ml (Zenacts Pharma (Kaizen Drugs (P) Ltd))$ 1.08
Isofer 100mg/ml Injection (Zenacts Pharma (Kaizen Drugs (P) Ltd))$ 9.21
1.5ml (Cosme Farma Laboratories Ltd (CFL Pharmaceuticals Ltd))$ 0.30
Jecktofer Plus Iron 75 mg/1.5 mL, folic acid750 mcg/1.5 mL, vitamin B12 75mcg/1.5 mL. INJ / 1.5ml (Cosme Farma Laboratories Ltd (CFL Pharmaceuticals Ltd))$ 0.30
Jecktofer Plus Inj Injection (Cosme Farma Laboratories Ltd (CFL Pharmaceuticals Ltd))$ 0.30
Jecktofer Plus Iron 75 mg/1.5 mL, folic acid750 mcg/1.5 mL, vitamin B12 75mcg/1.5 mL. INJ / 1.5ml (Cosme Farma Laboratories Ltd (CFL Pharmaceuticals Ltd))$ 0.30

References

  1. PubChem. "Iron". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Iron". http://www.drugbank.ca/drugs/DB01592 (accessed September 17, 2018).
  3. MeSH. "Trace Elements". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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