Klordiazepoxid Actavis is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Klordiazepoxid Actavis affects chemicals in the brain that may become unbalanced and cause anxiety.
Klordiazepoxid Actavis is used to treat anxiety disorders or alcohol withdrawal.
Klordiazepoxid Actavis may also be used for other purposes not listed in this medication guide.
Klordiazepoxid Actavis indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Klordiazepoxid Actavis Hydrochloride Capsule is indicated for the management of anxiety disorders or for the short term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.
The effectiveness of Klordiazepoxid Actavis Hydrochloride Capsule in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individual patient.
How should I use Klordiazepoxid Actavis?
Use Klordiazepoxid Actavis injection as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Klordiazepoxid Actavis injection is usually administered as an injection at your doctor's office, hospital, or clinic.
If you are using Klordiazepoxid Actavis injection at home, carefully follow the injection procedures taught to you by your health care provider.
If the medicine contains particles or is discolored, or if the vial/container is cracked or damaged in any way, do not use it.
Try to stay in bed for 3 hours after taking Klordiazepoxid Actavis injection.
Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when full.
If you miss a dose of Klordiazepoxid Actavis injection and you are using it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Klordiazepoxid Actavis injection.
Uses of Klordiazepoxid Actavis in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Klordiazepoxid Actavis is used to treat anxiety and acute alcohol withdrawal. It is also used to relieve fear and anxiety before surgery. This medication belongs to a class of drugs called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA).
How to use Klordiazepoxid Actavis
Take this medication by mouth as directed by your doctor. The dosage is based on your age, medical condition, and response to treatment.
Use this medication exactly as prescribed. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. Also, if used for an extended period of time, do not suddenly stop using this drug without your doctor's approval. Some conditions may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased to avoid side effects such as seizures.
When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.
Klordiazepoxid Actavis description
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A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Klordiazepoxid Actavis has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia but has largely been superseded by the benzodiazepines. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) Klordiazepoxid Actavis is a controlled substance in the U.S.
Klordiazepoxid Actavis dosage
Klordiazepoxid Actavis Dosage
Applies to the following strength(s): 5 mg; 10 mg; 25 mg; 100 mg
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
Anxiety
Light Sedation
Alcohol Withdrawal
Usual Geriatric Dose for:
Anxiety
Usual Pediatric Dose for:
Anxiety
Additional dosage information:
Renal Dose Adjustments
Liver Dose Adjustments
Precautions
Dialysis
Other Comments
Usual Adult Dose for Anxiety
Mild to moderate anxiety: 5 or 10 mg orally, 3 or 4 times per day
Severe anxiety: 20 or 25 mg orally, 3 or 4 times per day
Use: Relief of mild, moderate, and severe anxiety disorders
Usual Adult Dose for Light Sedation
On days preceding surgery, 5 to 10 mg orally, 3 or 4 times per day
Use: Relief of preoperative apprehension and anxiety
Usual Adult Dose for Alcohol Withdrawal
50 to 100 mg orally, followed by repeated doses as needed until agitation is controlled
Maximum dose: 300 mg orally per day
Use: Relief of withdrawal symptoms of acute alcoholism
Usual Geriatric Dose for Anxiety
Elderly or debilitated patients:
5 mg orally, 2 to 4 times per day
Use: Relief of mild, moderate, and severe anxiety disorders
Usual Pediatric Dose for Anxiety
6 years or older:
5 mg orally, 2 to 4 times per day; this may be increased to 10 mg orally, 2 to 3 times per day
Use: Relief of mild, moderate, and severe anxiety disorders
Renal Dose Adjustments
Renal impairment: Use with caution
Liver Dose Adjustments
Hepatic impairment: Use with caution
Precautions
Safety and efficacy have not been established in patients younger than 6 years.
Consult WARNINGS section for additional precautions.
US Controlled Substance: Schedule IV
Dialysis
Data not available
Other Comments
Storage requirements:
-Protect from light
Monitoring:
-Psychiatric: Patients with a history of alcohol or drug abuse, or patients with a marked personality disorder should be monitored frequently.
Patient advice:
-Patients should be cautioned against performing activities requiring complete mental alertness, such as operating machinery or driving a motor vehicle.
- antipsychotic drugs (neuroleptics), antidepressants, sedatives, hypnotics, anesthetics, analgesics, ethanol enhanced the inhibitory effect on central nervous system, especially when administered parenterally.
- concomitant use of antacids can delay but not reduce the absorption of Klordiazepoxid Actavis.
- hormonal contraceptives increases the effectiveness of Klordiazepoxid Actavis.
- with muscle relaxants may enhance the action of muscle relaxants, with levodopa - may suppress antiparkinsonian action.
- theophylline at low doses perverts sedative effect of Klordiazepoxid Actavis.
- phenobarbital and phenytoin may accelerate the metabolism of Klordiazepoxid Actavis. In rare cases this medication inhibits the metabolism and enhances the action of phenytoin.
- may increase the toxicity of cyclophosphamide.
- cimetidine, omeprazole, disulfiram may increase the intensity and duration of action of this medicine.
Applies to Klordiazepoxid Actavis: oral capsule, oral tablet
As well as its needed effects, Klordiazepoxid Actavis (the active ingredient contained in Klordiazepoxid Actavis) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking Klordiazepoxid Actavis, check with your doctor immediately:
Rare
Fainting
mood or mental changes
shakiness and unsteady walk
unsteadiness, trembling, or other problems with muscle control or coordination
Incidence not known:
Abdominal and muscle cramps
chills
clay-colored stools
convulsions
cough or hoarseness
dark urine
difficulty in speaking
dizziness
drooling
fever with or without chills
general feeling of tiredness or weakness
headache
itching
light-colored stools
loss of appetite
loss of balance control
lower back or side pain
muscle trembling, jerking, or stiffness
nausea and vomiting
painful or difficult urination
pale skin
rash
restlessness
shakiness in the legs, arms, hands, or feet
shuffling walk
sleeplessness
sore throat
sores, ulcers, or white spots on the lips or in the mouth
stiffness of the limbs
stomach pain
sweating
swelling
trouble sleeping
twisting movements of the body
unable to sleep
uncontrolled movements, especially of the face, neck, and back
unpleasant breath odor
unusual bruising or bleeding
unusual tiredness or weakness
vomiting of blood
yellow eyes or skin
If any of the following symptoms of overdose occur while taking Klordiazepoxid Actavis, get emergency help immediately:
Symptoms of overdose:
Change in consciousness
lack of coordination
loss of consciousness
sleepiness or unusual drowsiness
Minor Side Effects
Some Klordiazepoxid Actavis side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
Incidence not known:
Decreased interest in sexual intercourse
difficulty having a bowel movement (stool)
inability to have or keep an erection
increased in sexual ability, desire, drive, or performance
increased interest in sexual intercourse
loss in sexual ability, desire, drive, or performance
this medicine is contraindicated in the presence of glaucoma (since the anticholinergic component may produce some degree of mydriasis) and in patients with prostatic hypertrophy and benign bladder neck obstruction. It is contraindicated in patients with known hypersensitivity to Klordiazepoxid Actavis hydrochloride and/or clidinium bromide.
Active ingredient matches for Klordiazepoxid Actavis:
DailyMed. "AMITRIPTYLINE HYDROCHLORIDE; CHLORDIAZEPOXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
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