Levofloxacin 0.5.% Pfizer Uses

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What is Levofloxacin 0.5.% Pfizer?

Treating infections caused by certain bacteria. It is also used to prevent or treat anthrax or plague in certain patients.

Levofloxacin 0.5.% Pfizer is a quinolone antibiotic. It works by killing sensitive bacteria.

Levofloxacin 0.5.% Pfizer indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Levofloxacin 0.5.% Pfizer and other antibacterial drugs, Levofloxacin 0.5.% Pfizer should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Treatment of adults (≥18 years) with mild, moderate and severe infections caused by susceptible strains of the designated microorganisms in the conditions listed as follows. Levofloxacin 0.5.% Pfizer is indicated when IV administration offers a route of administration advantageous to the patient (eg, patient cannot tolerate an oral dosage form).

Acute maxillary sinusitis due to Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis.

Acute bacterial exacerbation of chronic bronchitis due to Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae or Moraxella catarrhalis.

Nosocomial pneumonia due to methicillin-susceptible Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae or Streptococcus pneumoniae. Adjunctive therapy should be used as clinically indicated. Where Pseudomonas aeruginosa is a documented or presumptive pathogen, combination therapy with an anti-pseudomonal β-lactam is recommended.

Community-acquired pneumonia due to Staphylococcus aureus, Streptococcus pneumoniae [including multi-drug resistant strains (MDRSP)*], Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila or Mycoplasma pneumoniae.

Complicated skin and skin structure infections due to methicillin-susceptible Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes or Proteus mirabilis.

Uncomplicated skin and skin structure infections (mild to moderate) including abscesses, cellulitis, furuncles, impetigo, pyoderma, wound infections, due to Staphylococcus aureus or Streptococcus pyogenes.

Chronic bacterial prostatitis due to Escherichia coli, Enterococcus faecalis or Staphylococcus epidermidis.

Complicated urinary tract infections (mild to moderate) due to Enterococcus faecalis, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis or Pseudomonas aeruginosa.

Acute pyelonephritis (mild to moderate) caused by Escherichia coli.

Uncomplicated urinary tract infections (mild to moderate) due to Escherichia coli, Klebsiella pneumoniae or Staphylococcus saprophyticus.

How should I use Levofloxacin 0.5.% Pfizer?

Use Levofloxacin 0.5.% Pfizer solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Levofloxacin 0.5.% Pfizer solution comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Levofloxacin 0.5.% Pfizer solution refilled.
  • Take Levofloxacin 0.5.% Pfizer solution by mouth on an empty stomach at least 1 hour before or 2 hours after eating.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Drinking extra fluids while you are taking Levofloxacin 0.5.% Pfizer solution is recommended. Check with your doctor for instructions.
  • Do not take a product that has magnesium, aluminum, calcium, zinc, or iron in it within 2 hours before or 2 hours after you take Levofloxacin 0.5.% Pfizer solution. Examples of these products include certain antacids, multivitamins, quinapril, and calcium-fortified orange juice. Check with your doctor or pharmacist if you have a question about whether you should separate Levofloxacin 0.5.% Pfizer solution from a certain food or product.
  • If you also take sucralfate or didanosine, do not take them within 2 hours before or 2 hours after taking Levofloxacin 0.5.% Pfizer solution. Check with your doctor if you have questions.
  • Levofloxacin 0.5.% Pfizer solution works best if it is taken at the same time each day.
  • To clear up your infection completely, take Levofloxacin 0.5.% Pfizer solution for the full course of treatment. Keep taking it even if you feel better in a few days.
  • Do not miss any doses of Levofloxacin 0.5.% Pfizer solution. If you miss a dose of Levofloxacin 0.5.% Pfizer solution, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once or more than 1 dose in 1 day.

Ask your health care provider any questions you may have about how to use Levofloxacin 0.5.% Pfizer solution.

Uses of Levofloxacin 0.5.% Pfizer in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Levofloxacin 0.5.% Pfizer is used to treat bacterial infections of the respiratory tract, urinary tract, ear, tooth and prostate gland. It is also used to treat skin and soft tissue infections, anthrax and plague.

Levofloxacin 0.5.% Pfizer description

infoPharmacology is a crucial part of medicine wherein various medications are used to advance the well-being of an individual. Some drugs cure the infection or a disease; few prevent the occurrence of a symptom or a disease, and few are used in long-term treatment of the disease. Drugs are obtained from the plants as well as they can be synthesized organically. The drugs are used in various combinations or a single drug by the pharmaceutical industry during its preparation. The half-life of each medicine is different, and the dosage of the drug depends on the half-life of the drug.

Each tablet contains Levofloxacin 0.5.% Pfizer 250 mg as active ingredient corresponding to Levofloxacin 0.5.% Pfizer hemihydrate 256.23 mg.

Cravit IV also contains the following inactive ingredients: Sodium chloride; sodium hydroxide; hydrochloric acid (qs: pH 4.8) and water for injection for a volume of 100 mL (Na+ concentration: 154 mmol/L).

Levofloxacin 0.5.% Pfizer is a synthetic broad-spectrum antibacterial agent for oral and IV administration. Chemically, Levofloxacin 0.5.% Pfizer, a chiral fluorinated carboxyquinolone, is the pure (-)-(S)-enantiomer of the racemic drug substance ofloxacin. Levofloxacin 0.5.% Pfizer is (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4 benzoxazine-6-carboxylic acid hemihydrate.

Its empirical formula is C18H20FN3O4·½H2O and its molecular weight is 370.38.

Levofloxacin 0.5.% Pfizer is a light yellowish-white to yellow-white crystal or crystalline powder. The molecule exists as a zwitterion at the pH conditions in the small intestine. The data demonstrate that from pH 0.6-5.8, the solubility of Levofloxacin 0.5.% Pfizer is essentially constant (approximately 100 mg/mL). Levofloxacin 0.5.% Pfizer is considered soluble to freely soluble in this pH range, as defined by USP nomenclature. Above pH 5.8, the solubility increases rapidly to its maximum at pH 6.7 (272 mg/mL) and is considered freely soluble in this range. Above pH 6.7, the solubility decreases and reaches a minimum value (about 50 mg/mL) at a pH of approximately 6.9. Levofloxacin 0.5.% Pfizer has the potential to form stable coordination compounds with many metal ions. This in vitro chelation potential has the following formation order: A1+3 > Cu+2 > Zn+2 > Mg+2 > Ca+2.


Active ingredient matches for Levofloxacin 0.5.% Pfizer:

Levofloxacin in Japan.

List of Levofloxacin 0.5.% Pfizer substitutes (brand and generic names)

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  1. DailyMed. "LEVOFLOXACIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailymed/se... (accessed September 18, 2017).
  2. Wikipedia. "levofloxacin anhydrous: Link to the compound information in Wikipedia.". https://en.wikipedia.org/wiki/Levofloxac... (accessed September 18, 2017).
  3. PubChem. "LEVOFLOXACIN". https://pubchem.ncbi.nlm.nih.gov/compoun... (accessed September 18, 2017).
  4. FDA Orange Book. "Patent:6806256: The publication, Approved Drug Products with Therapeutic Equivalence Evaluations (the List, commonly known as the Orange Book), identifies drug products approved on the basis of safety and effectiveness by the Food and Drug Administration (FDA) under the Federal Food, Drug, and Cosmetic Act (the Act).". https://www.fda.gov/Drugs/InformationOnD... (accessed September 18, 2017).


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