Lidocaine Uses

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How do you administer this medicine?
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What is Lidocaine?

Lidocaine topical jelly or ointment is used on different parts of the body to cause numbness or loss of feeling for patients having certain medical procedures. It is also used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, minor cuts, or scratches.

Lidocaine viscous topical solution is also used to treat sore mouth or throat and also reduce gagging during the taking of X-ray pictures and dental impressions.

Lidocaine skin patch is used to relieve pain caused by shingles (postherpetic neuralgia).

Lidocaine belongs to the family of medicines called local anesthetics. Lidocaine prevents pain by blocking the signals at the nerve endings in the skin. Lidocaine does not cause unconsciousness as general anesthetics do when used for surgery.

Lidocaine is available only with your doctor's prescription.

Lidocaine indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Lidocaine is indicated in the management of cardiac arrhythmias, particularly those of ventricular origin, such as occur with acute myocardial infarction.

The selection of the intramuscular route of administration (single dose) is justified in the following circumstances:

  1. By a physician in whose opinion the potential benefits outweigh the possible risks even when ECG equipment is not available to verify the arrhythmia.
  2. By, or under the supervision of, a physician, including mobile coronary care units, when facilities for intravenous administration are not readily available, or under circumstances where maintaining continuous intravenous therapy is difficult or impossible.
  3. For use in the pre-hospital phase of suspected acute myocardial infarction by a patient who has transmitted his electrocardiogram with a CardioBeeper®, whose electrocardiogram demonstrates the presence of a ventricular arrhythmia and who is instructed by qualified medical personnel to self-administer the Lidocaine® Auto-Injector.

How should I use Lidocaine?

Use Lidocaine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Lidocaine.

Uses of Lidocaine in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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It is used to numb an area of body for temporary relief of pain caused by recurrent mouth ulcers, denture irritation, anal or rectal problems. It is also used before minor surgeries as local anesthetic.

Lidocaine description

A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacaine or prilocaine. [PubChem]

Lidocaine dosage

A physician who prescribes this device for the patient, must take appropriate steps to insure that his patient understands the indications and use of this device including review with the patient, in detail, the patient package insert and operation of the Auto-Injector.

Inject the contents of 1 Lidocaine® Auto-Injector (300 mg Lidocaine, 3 mL, 10% solution) intramuscularly into the anterolateral aspect of the thigh or deltoid region of the arm. See DETAILED INSTRUCTIONS below.

As soon as possible, and when indicated, patients should be changed to an intravenous infusion of Lidocaine or to an oral antiarrhythmic preparation for maintenance therapy. However, if necessary, an additional intramuscular injection may be made after an interval of 60-90 minutes. IT SHOULD BE MADE CLEAR TO THE PATIENT THAT THIS SECOND INJECTION SHOULD NOT BE MADE WITHOUT FURTHER INSTRUCTIONS BY QUALIFIED MEDICAL PERSONNEL.

DETAILED INSTRUCTIONS

NOTE: A separate booklet containing information regarding self-administration of the Lidocaine®Auto-Injector by patients equipped with a CardioBeeper®will be made available to the patient.

Introduction:

As part of the early management of a heart attack, your physician has prescribed for you a drug — Lidocaine contained in an automatic injector — The Lidocaine® Auto-Injector.

This drug has been shown to be valuable in the management of certain abnormal heart rhythms which sometimes accompany heart attacks. As with all other drugs, it is not without risk. UNDER NO CIRCUMSTANCES SHOULD IT BE USED WITHOUT SPECIFIC INSTRUCTIONS TO DO SO BY QUALIFIED MEDICAL PERSONNEL.

Therefore, your physician has taken steps to provide you with a CardioBeeper® with which to transmit your heart rate and rhythm by conventional telephone.

Be certain to review the information contained in this booklet and practice with the use of the CardioBeeper®.

The Lidocaine® Auto-Injector:

The Lidocaine® Auto-Injector is a disposable, prefilled automatic injection device containing 300 mg Lidocaine.

When to use the Lidocaine® Auto-Injector:

If you experience the signs and symptoms described to you by your physician as suggesting a possible heart attack, immediately telephone your physician, or center designated by your physician, and transmit your electrocardiogram by CardioBeeper®. You will then be instructed whether or not you are to use the Lidocaine® Auto-Injector.

Directions for Use:

When as described above, you have been instructed to use the Lidocaine® Auto-Injector, proceed as follows:

  1. Remove gray safety cap.
  2. Place black end on thickest part of thigh and press hard until injector functions.
  3. Hold firmly in place for ten seconds, then remove. Massage the area of injection for 10 seconds.

UNLESS ABSOLUTELY NECESSARY, DO NOT ATTEMPT TO OPERATE A MOTOR VEHICLE AFTER USE OF THE Lidocaine® Auto-Injector.

Proceed as instructed by physician.

Lidocaine interactions

See also:
What other drugs will affect Lidocaine?

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Beta-blockers increase the risk of bradycardia and hypotension. Norepinephrine and beta-blockers by reducing hepatic blood flow decrease (increased toxicity), isadrine and glucagon - increase the clearance of Lidocaine. Cimetidine increases the plasma concentration of Lidocaine Euro-Med Laboratories Phil (displaces from its association with proteins and slows inactivation in the liver). Barbiturates causing induction of microsomal enzymes stimulate the degradation of Lidocaine and reduce its activity. Anticonvulsants (hydantoin derivatives) accelerate the biotransformation in the liver (decreased concentration in the blood), for IV injections it may increases cardiodepressive action of Lidocaine. Antiarrhythmics (amiodarone, verapamil, quinidine, aymalin) potentiate cardiac depression. Combination with novocainamide may cause CNS excitement and hallucinations. Lidocaine Euro-Med Laboratories Phil strengthens the inhibitory effect of anesthesia (hexobarbital, thiopental sodium), hypnotics and sedatives on the respiratory center, weakens the cardiac effects of digitoxin, enhances muscle relaxation caused by drugs curare like (possible paralysis of respiratory muscles). MAO inhibitors prolong local anesthesia.

Lidocaine side effects

See also:
What are the possible side effects of Lidocaine?

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Systemic

Adverse experiences following the administration of Lidocaine are similar in nature to those observed with other amide local anesthetic agents. These adverse experiences are, in general, dose-related and may result from high plasma levels caused by excessive dosage, rapid absorption or inadvertent intravascular injection, or may result from a hypersensitivity, idiosyncrasy or diminished tolerance on the part of the patient. Serious adverse experiences are generally systemic in nature. The following types are those most commonly reported:

Central Nervous System

CNS manifestations are excitatory and/or depressant and may be characterized by lightheadedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression and arrest. The excitatory manifestations may be very brief or may not occur at all, in which case the first manifestation of toxicity may be drowsiness merging into unconsciousness and respiratory arrest.

Drowsiness following the administration of Lidocaine is usually an early sign of a high blood level of the drug and may occur as a consequence of rapid absorption.

Cardiovascular System

Cardiovascular manifestations are usually depressant and are characterized by bradycardia, hypotension, and cardiovascular collapse, which may lead to cardiac arrest.

Allergic

Allergic reactions are characterized by cutaneous lesions, urticaria, edema or anaphylactoid reactions. Allergic reactions may occur as a result of sensitivity to local anesthetic agents. Allergic reactions as result of sensitivity to Lidocaine are extremely rare and, if they occur, should be managed by conventional means. The detection of sensitivity by skin testing is of doubtful value.

Neurologic

The incidences of adverse reactions associated with the use of local anesthetics may be related to the total dose of local anesthetic administered and are also dependent upon the particular drug used, the route of administration and the physical status of the patient. In a prospective review of 10,440 patients who received Lidocaine for spinal anesthesia, the incidences of adverse reactions were reported to be about 3 percent each for positional headaches, hypotension and backache; 2 percent for shivering; and less than 1 percent each for peripheral nerve symptoms, nausea, respiratory inadequacy and double vision. Many of these observations may be related to local anesthetic techniques, with or without a contribution from the local anesthetic.

In the practice of caudal or lumbar epidural block, occasional unintentional penetration of the subarachnoid space by the catheter may occur. Subsequent adverse effects may depend partially on the amount of drug administered subdurally. These may include spinal block of varying magnitude (including total spinal block), hypotension secondary to spinal block, loss of bladder and bowel control, and loss of perineal sensation and sexual function. Persistent motor, sensory and/or autonomic (sphincter control) deficit of some lower spinal segments with slow recovery (several months) or incomplete recovery have been reported in rare instances when caudal or lumbar epidural block has been attempted. Backache and headache have also been noted following use of these anesthetic procedures.

There have been reported cases of permanent injury to extraocular muscles requiring surgical repair following retrobulbar administration.

Lidocaine contraindications

See also:
What is the most important information I should know about Lidocaine?

Severe bleeding, shock, hypotension, infection of the proposed injection site, marked bradycardia, cardiogenic shock, severe forms of chronic heart failure, SSS in elderly patients, AV-block II and III degree (except in cases when the probe was introduced to stimulate the ventricles), severe liver function abnormalities.

For subarachnoid anesthesia - complete heart block, bleeding, hypotension, shock, infection of the venue lumbar puncture, septicemia.

Increased sensitivity to Lidocaine Euro-Med Laboratories Phil and other amide type local anesthetics.

Active ingredient matches for Lidocaine:

Lidocaine Hydrochloride in Argentina, Austria, Bahrain, Belgium, Brazil, Bulgaria, Canada, China, Czech Republic, Denmark, Finland, France, Georgia, Germany, Greece, Hong Kong, Hongkong, Iceland, Indonesia, Israel, Italy, Latvia, Malaysia, Malta, Netherlands, New Zealand, Norway, Oman, Peru, Philippines, Poland, Portugal, Russian Federation, Singapore, South Africa, Spain, Sweden, Switzerland, Taiwan, Thailand, Tunisia, Turkey, United Kingdom, United States, Vietnam.

Lidocaine Hcl

Lidocaine


Unit description / dosage (Manufacturer)Price, USD
Injectable; Injection; 1%
Injectable; Injection; 2%
Jelly; Topical; Lidocaine Hydrochloride 2%
Injectable; Injection; Lidocaine Hydrochloride 1%
Injectable; Injection; Lidocaine Hydrochloride 2%
Injectable; Injection; Lidocaine Hydrochloride 10%
Injectable; Injection; Lidocaine Hydrochloride 0.5%
Injectable; Injection; Lidocaine Hydrochloride 1.5%
Solution; Topical; Lidocaine Hydrochloride 4%
Injectable; Injection; Lidocaine Hydrochloride 10 mg / ml
Solution; Oral; Lidocaine Hydrochloride 2%
Jelly; Topical; 2%
Gel; Local; Lidocaine Hydrochloride 5%
Drops; Ophthalmic; Lidocaine Hydrochloride 4%
Injectable; Injection; Epinephrine Racemic 0.01 mg; Lidocaine Hydrochloride 20 mg / ml
Ointment; Topical; Lidocaine 5%
Injectable; Injection; 1.5%
Injectable; Injection; 20%
Injectable; Injection; 4%
Liquid; Block / Infiltration; Lidocaine Hydrochloride 2%
Solution; Block / Infiltration; Lidocaine Hydrochloride 1%
Film, Extended Release; Buccal; Lidocaine 23 mg / patch
Film, Extended Release; Buccal; Lidocaine 46.1 mg / patch
Injectable; Injection; Lidocaine Hydrochloride 4%
Injectable; Injection; Lidocaine Hydrochloride 20%
Drops; Ophthalmic; Lidocaine Hydrochloride 2%
Injectable; Injection; Epinephrine Hydrochloride 1 mcg; Lidocaine Hydrochloride 20 mg / ml
Injectable; Injection; Lidocaine Hydrochloride Dihydrate 10 mg / ml
Solution; Local Oral; Lidocaine Hydrochloride 50 mg / ml
Rocephin 10 gm vial$ 478.32
Lidocaine HCl 3% Lotion 177ml Bottle$ 230.30
Rocephin 2 gm vial$ 97.50
Rocephin 1 gm vial$ 62.02
EMLA 2.5-2.5% Cream 30 gm Tube$ 58.40
Lidocaine-Prilocaine 2.5-2.5% Cream 30 gm Tube$ 47.79
Lidocaine HCl 2% Gel 10ml Syringe$ 17.99
Lidocaine HCl 2% Gel 30ml Tube$ 17.99
Lidocaine HCl 4% Solution 50ml Bottle$ 16.99
Lidocaine Viscous 2% Solution 100ml Bottle$ 13.99
Lidocaine hcl 1% syringe$ 9.76
Lidocaine HCl 4% Solution 4ml Bottle$ 9.42
Lidoderm 1 Box = 30 Patches$ 8.03
Akten 3.5% drops$ 7.50
Lidocaine 5% in d7.5w ampul$ 3.06
Lidocaine 3% cream$ 2.91
Lidamantle 3% cream$ 2.03
Zilactin-l cold sore liquid$ 0.99
Xylocaine 2% jelly$ 0.68
Lidocaine hcl 10% vial$ 0.55
Xylocaine 5% ointment$ 0.42
Xylocaine Jelly 2 % Jelly$ 0.41
Xylocaine 2% Solution$ 0.34
Xylocaine 5 % Ointment$ 0.29
Lidocaine HCl 1% Solution$ 0.24
Lidocaine hcl powder$ 0.24
Lidocaine base powder$ 0.22
Lidocaine hcl 4% solution$ 0.18
Xylocaine 0.5% vial$ 0.18
Lidodan 5 % Ointment$ 0.16
Xylocaine Viscous 2 % Liquid$ 0.10
Lidocaine hcl 0.5% vial$ 0.08
Solarcaine aerosol$ 0.06
Lidodan Viscous 2 % Liquid$ 0.06
Lidocaine 2% viscous solution$ 0.03
Lidocaine / Tai Yu 2 % x 2 mL
Lidocaine / Tai Yu 2 % x 20 mL
Lidocaine / Astar 20 mg/1 mL x 1's
Lidocaine / Oriental 2 % x 20 mL
Lidocaine / Yihhaw 4 % x 4000 mL
Lidocaine / Chi Sheng 2 % x 2 mL
Lidocaine / Chi Sheng 2 % x 20 mL
Injectable; Injection; Lidocaine Hydrochloride 5 mg / ml
Injectable; Injection; Lidocaine Hydrochloride 15 mg / ml
Injectable; Injection; Lidocaine Hydrochloride 20 mg / ml
Lidocaine patch 700 mg/1 (Qualitest Pharmaceuticals (US))
Lidocaine injection, solution 20 mg/mL (Cardinal Health (US))
Lidocaine ointment 50 mg/g (Preferred Pharmaceuticals Inc. (US))
Lidocaine injection, solution 10 mg/mL (Cardinal Health (US))
Lidocaine jelly 20 mg/mL (Akorn, Inc. (US))
Lidocaine patch 140 mg/1 (Mylan Pharmaceuticals Inc. (US))
Lidocaine ointment 5 g/100g (Unit Dose Services (US))
Lidocaine ointment 35.44 g/g (Solubiomix (US))
Lidocaine cream 40 mg/g (County Line Pharmaceuticals, LLC (US))
Lidocaine cream 50 mg/g (County Line Pharamceuticals (US))
Lidocaine aerosol, spray .64 g/127g (Premier Brands of America Inc. (US))
Lidocaine cream 4 g/100g (Pd Rx Pharmaceuticals, Inc. (US))

List of Lidocaine substitutes (brand and generic names):

Injectable; Injection; Lidocaine Hydrochloride 100 mg / 100 ml
Injectable; Injection; Lidocaine Hydrochloride 200 mg / 100 ml
Injectable; Injection; Lidocaine Hydrochloride 400 mg / 100 ml
Injectable; Injection; Lidocaine Hydrochloride 4%
Injectable; Injection; Lidocaine Hydrochloride 800 mg / 100 ml
Lidocaine 5% cream 5 g/100g (Tri Marc Labs (US))
Injectable; Spinal; Lidocaine Hydrochloride 5%
Injectable; Injection; Lidocaine Hydrochloride 1%
Injectable; Injection; Lidocaine Hydrochloride 2%
Lidocaine Free-Preservative GPO inj 2 % 2 mL x 10 x 1's (GPO)
Lidocaine Free-Preservative GPO inj 2 % 10 mL x 10 x 1's (GPO)
Lidocaine GPO 1 % x 20 mL x 10's (GPO)
Lidocaine GPO 1 % x 50 mL x 5's (GPO)
Lidocaine GPO 2 % x 20 mL x 10's (GPO)
Lidocaine GPO 2 % x 50 mL x 5's (GPO)

References

  1. DailyMed. "LIDOCAINE; TETRACAINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "lidocaine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "lidocaine". http://www.drugbank.ca/drugs/DB00281 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Lidocaine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Lidocaine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Lidocaine drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Not useful1
100.0%


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Lidocaine drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive1
100.0%


1 consumer reported time for results

To what extent do I have to use Lidocaine before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Lidocaine. To get the time effectiveness of using Lidocaine drug by other patients, please click here.
Users%
1 month1
100.0%


Consumer reported age

No survey data has been collected yet


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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