Loniten Uses

How times a day do you take this medicine?
sponsored

What is Loniten?

Loniten belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension).

High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Loniten works by relaxing blood vessels so that blood passes through them more easily. This helps to lower blood pressure.

Loniten has other effects that could be bothersome for some patients. These include increased hair growth, weight gain, fast heartbeat, and chest pain. Before you take Loniten, be sure that you have discussed the use of it with your doctor.

Loniten is being applied to the scalp in liquid form by some balding men to stimulate hair growth. However, improper use of liquids made from Loniten tablets can result in Loniten being absorbed into the body, where it may cause unwanted effects on the heart and blood vessels.

Loniten is available only with your doctor's prescription.

Loniten indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
sponsored

Because of the potential for serious adverse effects, Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) tablets are indicated only in the treatment of hypertension that is symptomatic or associated with target organ damage and is not manageable with maximum therapeutic doses of a diuretic plus two other antihypertensive drugs. At the present time use in milder degrees of hypertension is not recommended because the benefit-risk relationship in such patients has not been defined. Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) reduced supine diastolic blood pressure by 20 mm Hg or to 90 mm Hg or less in approximately 75% of patients, most of whom had hypertension that could not be controlled by other drugs.

How should I use Loniten?

Use Loniten foam (for men) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Loniten foam (for men).

Uses of Loniten in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
sponsored

Loniten solution and foam are used to help hair growth in the treatment of male pattern baldness. It is not used for baldness at the front of the scalp or receding hairline in men. The foam and 2 percent Loniten solution is also used to help hair growth in women with thinning hair.

Loniten belongs to a class of drugs known as vasodilators. It is not known how Loniten causes hair growth. This medication is not used for sudden/patchy hair loss, unexplained hair loss (e.g., no family history of hair loss), or hair loss after giving birth.

Do not use this product if you are 18 years old or younger.

How to use Loniten topical

Read and follow all directions on the product package before using this product. If you are uncertain about any of the information, consult your doctor or pharmacist.

Clean and dry the scalp area before applying the medication. You may apply this product to damp hair. To use the solution, fill the applicator with 1 milliliter of medication (to the 1 milliliter line), or use 20 drops. Part your hair in the area of thinning and apply the solution evenly to the affected area of the scalp. Gently rub in. Allow the solution to dry completely before using other styling products (e.g., gels, mousse) or before going to bed.

To use the foam, rinse your hands in cold water and dry well. Apply about 1/2 capful of foam to the scalp and rub in gently. Allow the foam to dry completely before styling or going to bed.

If scalp irritation is a problem, you may need to avoid using Loniten on the same days that you have your hair colored or chemically treated (e.g., permed).

Do not use on other parts of the body unless directed by your doctor. Do not use on skin that is red, painful, irritated, scraped, cut, or infected. Wash hands thoroughly after application. Avoid getting the medication in your eyes. If this occurs, rinse your eyes with large amounts of cool water.

Do not use this medication more often, apply more of it than as directed, or apply it to an irritated or sunburned scalp. Doing so can cause the drug to be absorbed into your body and result in serious side effects. This product may contain alcohol and can be irritating and drying to the scalp. Ask your doctor or pharmacist how to use this product safely.

It takes time for hair to regrow. Most people need to use this medication regularly for 4 months to see benefit. This medication must be used continuously to maintain hair growth. If your condition does not improve or worsens after using this medication for 4 to 6 months, or if you think you may have a serious medical problem, tell your doctor.

Loniten description

sponsored

A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)

Loniten dosage

Patients over 12 years of age

The recommended initial dosage of Loniten tablets is 5 mg of Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) given as a single daily dose. Daily dosage can be increased to 10, 20 and then to 40 mg in single or divided doses if required for optimum blood pressure control. The effective dosage range is usually 10 to 40 mg per day. The maximum recommended dosage is 100 mg per day.

Patients under 12 years of age

The initial dosage is 0.2 mg/kg Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) as a single daily dose. The dosage may be increased in 50 to 100% increments until optimum blood pressure control is achieved. The effective dosage range is usually 0.25 to 1 mg/kg/day. The maximum recommended dosage is 50 mg daily. Dose frequency: The magnitude of within-day fluctuation of arterial pressure during therapy with Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) is directly proportional to the extent of pressure reduction. If supine diastolic pressure has been reduced less than 30 mm Hg, the drug need be administered only once a day; if supine diastolic pressure has been reduced more than 30 mm Hg, the daily dosage should be divided into two equal parts.

Frequency of dosage adjustment

Dosage must be titrated carefully according to individual response. Intervals between dosage adjustments normally should be at least 3 days since the full response to a given dose is not obtained for at least that amount of time. Where a more rapid management of hypertension is required, dose adjustments can be made every 6 hours if the patient is carefully monitored.

Concomitant therapy: Diuretic and beta-blocker or other sympathetic nervous system suppressant.

Diuretics:Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) must be used in conjunction with a diuretic in patients relying on renal function for maintaining salt and water balance. Diuretics have been used at the following dosages when starting therapy with Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) : hydrochlorothiazide (50 mg, b.i.d.) or other thiazides at equieffective dosage; chlorthalidone (50 to 100 mg, once daily); furosemide (40 mg, b.i.d.). If excessive salt and water retention results in a weight gain of more than 5 pounds, diuretic therapy should be changed to furosemide; if the patient is already taking furosemide, dosage should be increased in accordance with the patient's requirements.

Beta-blocker or other sympathetic nervous system suppressants

When therapy with Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) is begun, the dosage of a beta-adrenergic receptor blocking drug should be the equivalent of 80 to 160 mg of propranolol per day in divided doses.

If beta-blockers are contraindicated, methyldopa (250 to 750 mg, b.i.d.) may be used instead. Methyldopa must be given for at least 24 hours before starting therapy with Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) because of the delay in the onset of methyldopa's action. Limited clinical experience indicates that clonidine may also be used to prevent tachycardia induced by Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets); the usual dosage is 0.1 to 0.2 mg twice daily.

Sympathetic nervous system suppressants may not completely prevent an increase in heart rate due to Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) but usually do prevent tachycardia. Typically, patients receiving a beta-blocker prior to initiation of therapy with Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) have a bradycardia and can be expected to have an increase in heart rate toward normal when Loniten is added. When treatment with Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) and beta-blocker or other sympathetic nervous system suppressant are begun simultaneously, their opposing cardiac effects usually nullify each other, leading to little change in heart rate.

How supplied

Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) Tablets USP 2.5 mg are 9/32", scored, round, white tablets imprinted "DAN 5642" and "2.5" supplied in bottles of 100 and 500.

Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) Tablets USP 10 mg are 9/32", scored, round, white tablets imprinted "DAN 5643" and "10" supplied in bottles of 100 and 500.

Dispense in a tight container with child-resistant closure.

Store at controlled room temperature 15°-30°C (59°-86°F).

Watson Laboratories, Inc. Corona, CA 92880, USA. Revised: October 2002. FDA Rev date: 6/8/2001

Loniten interactions

See also:
What other drugs will affect Loniten?

sponsored

Alfuzosin: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Amifostine: Blood Pressure Lowering Agents may enhance the hypotensive effect of Amifostine. Management: When amifostine is used at chemotherapy doses, blood pressure lowering medications should be withheld for 24 hours prior to amifostine administration. If blood pressure lowering therapy cannot be withheld, amifostine should not be administered. Consider therapy modification

Amphetamines: May diminish the antihypertensive effect of Antihypertensive Agents. Monitor therapy

Antipsychotic Agents (Second Generation [Atypical]): Blood Pressure Lowering Agents may enhance the hypotensive effect of Antipsychotic Agents (Second Generation [Atypical]). Monitor therapy

Atazanavir: May increase the serum concentration of Loniten (Systemic). Monitor therapy

Barbiturates: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Benperidol: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Brigatinib: May diminish the antihypertensive effect of Antihypertensive Agents. Brigatinib may enhance the bradycardic effect of Antihypertensive Agents. Monitor therapy

Brimonidine (Topical): May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Bromperidol: May diminish the hypotensive effect of Blood Pressure Lowering Agents. Blood Pressure Lowering Agents may enhance the hypotensive effect of Bromperidol. Avoid combination

CycloSPORINE (Systemic): May enhance the adverse/toxic effect of Loniten (Systemic). Severe hypertrichosis has been reported. Monitor therapy

Dapoxetine: May enhance the orthostatic hypotensive effect of Loniten (Systemic). Monitor therapy

Dexmethylphenidate: May diminish the therapeutic effect of Antihypertensive Agents. Monitor therapy

Diazoxide: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

DULoxetine: Blood Pressure Lowering Agents may enhance the hypotensive effect of DULoxetine. Monitor therapy

Herbs (Hypertensive Properties): May diminish the antihypertensive effect of Antihypertensive Agents. Monitor therapy

Herbs (Hypotensive Properties): May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Hypotension-Associated Agents: Blood Pressure Lowering Agents may enhance the hypotensive effect of Hypotension-Associated Agents. Monitor therapy

Levodopa-Containing Products: Blood Pressure Lowering Agents may enhance the hypotensive effect of Levodopa-Containing Products. Monitor therapy

Lormetazepam: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Methylphenidate: May diminish the antihypertensive effect of Antihypertensive Agents. Monitor therapy

Molsidomine: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Naftopidil: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Nicergoline: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Nicorandil: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Nitroprusside: Blood Pressure Lowering Agents may enhance the hypotensive effect of Nitroprusside. Monitor therapy

Obinutuzumab: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Management: Consider temporarily withholding blood pressure lowering medications beginning 12 hours prior to obinutuzumab infusion and continuing until 1 hour after the end of the infusion. Consider therapy modification

Pentoxifylline: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Pholcodine: Blood Pressure Lowering Agents may enhance the hypotensive effect of Pholcodine. Monitor therapy

Phosphodiesterase 5 Inhibitors: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Probenecid: May increase the serum concentration of Loniten (Systemic). Monitor therapy

Prostacyclin Analogues: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Quinagolide: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Monitor therapy

Valproate Products: May increase the serum concentration of Loniten (Systemic). Monitor therapy

Yohimbine: May diminish the antihypertensive effect of Antihypertensive Agents. Monitor therapy

Loniten side effects

See also:
What are the possible side effects of Loniten?

  1. Salt and Water Retention -Temporary edema developed in 7% of patients who were not edematous at the start of therapy.
  2. Pericarditis, Pericardial Effusion, and Tamponade.
  3. Dermatologic-Hypertrichosis-Elongation, thickening, and enhanced pigmentation of fine body hair are seen in about 80% of patients taking Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) tablets. This develops within 3 to 6 weeks after starting therapy. It is usually first noticed on the temples, between the eyebrows, between the hairline and the eyebrows, or in the side-burn area of the upper lateral cheek, later extending to the back, arms, legs, and scalp. Upon discontinuation of Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets), new hair growth stops, but 1 to 6 months may be required for restoration to pretreatment appearance. No endocrine abnormalities have been found to explain the abnormal hair growth; thus, it is hypertrichosis without virilism. Hair growth is especially disturbing to children and women and such patients should be thoroughly informed about this effect before therapy with Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) is begun. Allergic-Rashes have been reported, including rare reports of bullous eruptions, and Stevens-Johnson Syndrome.
  4. Hematologic-Thrombocytopenia and leukopenia (WBC < 3000/mm) have rarely been reported.
  5. Gastrointestinal-Nausea and/or vomiting has been reported. In clinical trials the incidence of nausea and vomiting associated with the underlying disease has shown a decrease from pretrial levels.
  6. Miscellaneous-Breast tenderness-This developed in less than 1% of patients.
  7. Altered Laboratory Findings-(a) ECG changes-Changes in direction and magnitude of the ECG T-waves occur in approximately 60% of patients treated with Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets). In rare instances a large negative amplitude of the T-wave may encroach upon the S-T segment, but the S-T segment is not independently altered. These changes usually disappear with continuance of treatment and revert to the pretreatment state if Loniten (Loniten (Loniten (Loniten tablets) tablets) tablets) is discontinued. No symptoms have been associated with these changes, nor have there been alterations in blood cell counts or in plasma enzymeconcentrations that would suggest myocardial damage. Long-term treatment of patients manifesting such changes has provided no evidence of deteriorating cardiac function. At present the changes appear to be nonspecific and without identifiable clinical significance. (b)-Effects of hemodilution-hematocrit, hemoglobin and erythrocyte count usually fall about 7% initially and then recover to pretreatment levels. (c) Other-Alkaline phosphatase increased varyingly without other evidence of liver or bone abnormality. Serum creatinine increased an average of 6% and BUN slightly more, but later declined to pretreatment levels.

Loniten contraindications

See also:
What is the most important information I should know about Loniten?

Loniten tablets should not be used to promote scalp hair growth.

You should not use this medication if you are allergic to Loniten, or if you have pheochromocytoma (adrenal gland tumor).

Before using Loniten, tell your doctor if you have angina (chest pain), congestive heart failure, kidney disease, epilepsy or other seizure disorder, or if you have recently had a heart attack.

Tell your doctor about all other medications you use, especially guanethidine (Ismelin).

Call your doctor at once if you have a serious side effect such as swelling in your legs or ankles, chest pain, fast or pounding heartbeats, trouble breathing, swelling or rapid weight gain, sudden numbness or problems with vision or speech, the first sign of any skin rash, or if you feel like you might pass out.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms, so you may not know when your blood pressure is high. You may need to use blood pressure medication for the rest of your life.

You may need to receive your first few doses of Loniten in a hospital setting where your heart and blood pressure can be monitored in case the medication causes serious side effects.



Active ingredient matches for Loniten:

Minoxidil in Australia, Austria, Brazil, Canada, Ireland, Italy, Portugal, Slovenia, Spain, Switzerland, Taiwan, Thailand, United Kingdom.


Unit description / dosage (Manufacturer)Price, USD
Tablet; Oral; Minoxidil 10 mg
Tablet; Oral; Minoxidil 2.5 mg
Tablet; Oral; Minoxidil 5 mg
Loniten 10 mg x 100's
Loniten 5 mg x 100's
100 tablet in 1 bottle
Tablets; Oral; Minoxidil 10 mg
Tablets; Oral; Minoxidil 2.5 mg
Tablets; Oral; Minoxidil 5 mg

List of Loniten substitutes (brand and generic names):

Lonitab 5mg Tablet (Intas)$ 0.45
Loniten 10mg tablet 10 mg (Pfizer Canada Inc (Canada))
Loniten 2.5mg tablet 2.5 mg (Pfizer Canada Inc (Canada))
Tablet; Oral; Minoxidil 10 mg (Pfizer)
Tablet; Oral; Minoxidil 2.5 mg (Pfizer)
Tablets; Oral; Minoxidil 10 mg (Pfizer)
Tablets; Oral; Minoxidil 2.5 mg (Pfizer)
Tablet; Oral; Minoxidil 10 mg (Pfizer)
Tablet; Oral; Minoxidil 5 mg (Pfizer)
Tablets; Oral; Minoxidil 10 mg (Pfizer)
Tablets; Oral; Minoxidil 5 mg (Pfizer)
Mandil 2% SOLN / 60ml$ 2.35
MANDIL SOLUTION 1 bottle / 60 ML solution each (Zee Laboratories)$ 2.35
Mandil NA Solution (Zee Laboratories)$ 2.35
MANEXIL 2% GEL 1 tube / 30 GM gel each (Dabur India Ltd)$ 1.22
MANEXIL 5% GEL 1 tube / 30 GM gel each (Dabur India Ltd)$ 3.05
MANEXIL 5% HAIR SPRAY 1 packet / 60 ML spray each (Dabur India Ltd)$ 7.54
Manexil 2% Gel (Dabur India Ltd)$ 1.22
Manexil 5% Spray (Dabur India Ltd)$ 7.54
Manexil 5%w/w Gel (Dabur India Ltd)$ 3.05
Manexil Gel 2% w/w 1g GEL / 30gm (Fem Care)$ 1.29
Manexil Gel 5% w/w 1g GEL / 2 tubes (Fem Care)$ 5.52
2 % w/w x 1 g x 30gm (Fem Care)$ 1.29
5 % w/w x 1 g x 2tubes (Fem Care)$ 5.52
MANEXIL GEL topical gel 2 % w/w x 30g (Fem Care)$ 1.29
MANEXIL GEL topical gel 5 % w/w x 30g (Fem Care)$ 2.76
Manoxidil 5 mg x 1, 000's (March Pharma)

References

  1. DailyMed. "MINOXIDIL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "minoxidil". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "minoxidil". http://www.drugbank.ca/drugs/DB00350 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Loniten are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Loniten. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Loniten before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Loniten. To get the time effectiveness of using Loniten drug by other patients, please click here.
Users%
1 month1
100.0%


Consumer reported age

No survey data has been collected yet


Consumer reviews


There are no reviews yet. Be the first to write one!


Your name: 
Email: 
Spam protection:  < Type 30 here

Information checked by Dr. Sachin Kumar, MD Pharmacology

| Privacy Policy
This site does not supply any medicines. It contains prices for information purposes only.
© 2003 - 2022 ndrugs.com All Rights Reserved